Skip to main content
Top
Published in: BMC Medicine 1/2013

Open Access 01-12-2013 | Commentary

Should we go nuts about nuts?

Authors: Sabine Rohrmann, David Faeh

Published in: BMC Medicine | Issue 1/2013

Login to get access

Abstract

Since the beginning of the 1990s, increasing evidence supports beneficial effects of nut consumption on health. A new analysis of the Spanish PREDIMED trial, published in BMC Medicine, has expanded our knowledge. The study showed that individuals eating nuts more than three times per week died less often from cardiovascular disease and cancer than non-consumers. The study also adds an important finding that previous epidemiological studies could not provide: a protective effect on premature mortality was only seen in the intervention group in which nut consumption increased during the 4.8 years of follow-up, not in the intervention group with additional olive oil consumption or in the control group. Nut consumption actually decreased during follow-up in the latter two groups. Questions remain to be answered on the quantity of nuts to be consumed for health benefits, on possible mechanisms of action, and on whether some types of nuts should be favored.
Literature
1.
go back to reference Fraser GE, Sabate J, Beeson WL, Strahan TM: A possible protective effect of nut consumption on risk of coronary heart disease. The Adventist Health Study. Arch Intern Med. 1992, 152 (7): 1416-1424. 10.1001/archinte.1992.00400190054010.CrossRefPubMed Fraser GE, Sabate J, Beeson WL, Strahan TM: A possible protective effect of nut consumption on risk of coronary heart disease. The Adventist Health Study. Arch Intern Med. 1992, 152 (7): 1416-1424. 10.1001/archinte.1992.00400190054010.CrossRefPubMed
2.
go back to reference Sabate J, Fraser GE, Burke K, Knutsen SF, Bennett H, Lindsted KD: Effects of walnuts on serum lipid levels and blood pressure in normal men. N Engl J Med. 1993, 328 (9): 603-607. 10.1056/NEJM199303043280902.CrossRefPubMed Sabate J, Fraser GE, Burke K, Knutsen SF, Bennett H, Lindsted KD: Effects of walnuts on serum lipid levels and blood pressure in normal men. N Engl J Med. 1993, 328 (9): 603-607. 10.1056/NEJM199303043280902.CrossRefPubMed
4.
go back to reference Guasch-Ferré M, Bulló M, Martínez-González MÁ, Ros E, Corella D, Estruch R, Fitó M, Arós F, Wärnberg J, Fiol M, et al: Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial. BMC Medicine. 2013, 11: 164-10.1186/1741-7015-11-164.CrossRefPubMedPubMedCentral Guasch-Ferré M, Bulló M, Martínez-González MÁ, Ros E, Corella D, Estruch R, Fitó M, Arós F, Wärnberg J, Fiol M, et al: Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial. BMC Medicine. 2013, 11: 164-10.1186/1741-7015-11-164.CrossRefPubMedPubMedCentral
5.
go back to reference Jenab M, Ferrari P, Slimani N, Norat T, Casagrande C, Overad K, Olsen A, Stripp C, Tjonneland A, Boutron-Ruault M-C, Clavel-Chapelon F, Kesse E, Nieters A, Bergmann M, Boeing H, Naska A, Trichopoulou A, Palli D, Krogh V, Celentano E, Tumino R, Sacerdote C, Bueno-de-Mesquita HB, Ocké MC, Peeters PH, Engeset D, Quirós JR, González CA, Martínez C, Chirlaque MD, et al: Association of nut and seed intake with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev. 2004, 13 (10): 1595-1603.PubMed Jenab M, Ferrari P, Slimani N, Norat T, Casagrande C, Overad K, Olsen A, Stripp C, Tjonneland A, Boutron-Ruault M-C, Clavel-Chapelon F, Kesse E, Nieters A, Bergmann M, Boeing H, Naska A, Trichopoulou A, Palli D, Krogh V, Celentano E, Tumino R, Sacerdote C, Bueno-de-Mesquita HB, Ocké MC, Peeters PH, Engeset D, Quirós JR, González CA, Martínez C, Chirlaque MD, et al: Association of nut and seed intake with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev. 2004, 13 (10): 1595-1603.PubMed
6.
go back to reference Jenab M, Sabate J, Slimani N, Ferrari P, Mazuir M, Casagrande C, Deharveng G, Tjonneland A, Olsen A, Overvad K, Boutron-Ruault MC, Clavel-Chapelon F, Boeing H, Weikert C, Linseisen J, Rohrmann S, Trichopoulou A, Naska A, Palli D, Sacerdote C, Tumino R, Mattiello A, Pala V, Bueno-de-Mesquita HB, Ocké MC, Peeters PH, Engeset D, Skeie G, Jakszyn P, Ardanaz E, et al: Consumption and portion sizes of tree nuts, peanuts and seeds in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts from 10 European countries. Br J Nutr. 2006, 96 (Suppl 2): S12-23.CrossRefPubMed Jenab M, Sabate J, Slimani N, Ferrari P, Mazuir M, Casagrande C, Deharveng G, Tjonneland A, Olsen A, Overvad K, Boutron-Ruault MC, Clavel-Chapelon F, Boeing H, Weikert C, Linseisen J, Rohrmann S, Trichopoulou A, Naska A, Palli D, Sacerdote C, Tumino R, Mattiello A, Pala V, Bueno-de-Mesquita HB, Ocké MC, Peeters PH, Engeset D, Skeie G, Jakszyn P, Ardanaz E, et al: Consumption and portion sizes of tree nuts, peanuts and seeds in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts from 10 European countries. Br J Nutr. 2006, 96 (Suppl 2): S12-23.CrossRefPubMed
7.
go back to reference O'Neil CE, Keast DR, Fulgoni VL, Nicklas TA: Tree nut consumption improves nutrient intake and diet quality in US adults: an analysis of National Health and Nutrition Examination Survey (NHANES) 1999–2004. Asia Pac J Clin Nutr. 2010, 19 (1): 142-150.PubMed O'Neil CE, Keast DR, Fulgoni VL, Nicklas TA: Tree nut consumption improves nutrient intake and diet quality in US adults: an analysis of National Health and Nutrition Examination Survey (NHANES) 1999–2004. Asia Pac J Clin Nutr. 2010, 19 (1): 142-150.PubMed
8.
go back to reference Estruch R, Ros E, Salas-Salvado J, Covas MI, Corella D, Aros F, Gomez-Gracia E, Ruiz-Gutierrez V, Fiol M, Lapetra J, Lamuela-Raventos RM, Serra-Majem L, Pintó X, Basora J, Muñoz MA, Sorlí JV, Martínez JA, Martínez-González MA, PREDIMED Study Investigators: Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013, 368 (14): 1279-1290. 10.1056/NEJMoa1200303.CrossRefPubMed Estruch R, Ros E, Salas-Salvado J, Covas MI, Corella D, Aros F, Gomez-Gracia E, Ruiz-Gutierrez V, Fiol M, Lapetra J, Lamuela-Raventos RM, Serra-Majem L, Pintó X, Basora J, Muñoz MA, Sorlí JV, Martínez JA, Martínez-González MA, PREDIMED Study Investigators: Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013, 368 (14): 1279-1290. 10.1056/NEJMoa1200303.CrossRefPubMed
9.
go back to reference King JC, Blumberg J, Ingwersen L, Jenab M, Tucker KL: Tree nuts and peanuts as components of a healthy diet. J Nutr. 2008, 138 (9): 1736S-1740S.PubMed King JC, Blumberg J, Ingwersen L, Jenab M, Tucker KL: Tree nuts and peanuts as components of a healthy diet. J Nutr. 2008, 138 (9): 1736S-1740S.PubMed
10.
go back to reference Vinson JA, Cai Y: Nuts, especially walnuts, have both antioxidant quantity and efficacy and exhibit significant potential health benefits. Food Funct. 2012, 3 (2): 134-140. 10.1039/c2fo10152a.CrossRefPubMed Vinson JA, Cai Y: Nuts, especially walnuts, have both antioxidant quantity and efficacy and exhibit significant potential health benefits. Food Funct. 2012, 3 (2): 134-140. 10.1039/c2fo10152a.CrossRefPubMed
11.
go back to reference Sabate J, Oda K, Ros E: Nut consumption and blood lipid levels: a pooled analysis of 25 intervention trials. Arch Intern Med. 2010, 170 (9): 821-827. 10.1001/archinternmed.2010.79.CrossRefPubMed Sabate J, Oda K, Ros E: Nut consumption and blood lipid levels: a pooled analysis of 25 intervention trials. Arch Intern Med. 2010, 170 (9): 821-827. 10.1001/archinternmed.2010.79.CrossRefPubMed
12.
go back to reference van den Brandt PA: The impact of a Mediterranean diet and healthy lifestyle on premature mortality in men and women. Am J Clin Nutr. 2011, 94 (3): 913-920. 10.3945/ajcn.110.008250.CrossRefPubMed van den Brandt PA: The impact of a Mediterranean diet and healthy lifestyle on premature mortality in men and women. Am J Clin Nutr. 2011, 94 (3): 913-920. 10.3945/ajcn.110.008250.CrossRefPubMed
13.
go back to reference Hu FB, Stampfer MJ, Manson JE, Rimm EB, Colditz GA, Rosner BA, Speizer FE, Hennekens CH, Willett WC: Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study. BMJ. 1998, 317 (7169): 1341-1345. 10.1136/bmj.317.7169.1341.CrossRefPubMedPubMedCentral Hu FB, Stampfer MJ, Manson JE, Rimm EB, Colditz GA, Rosner BA, Speizer FE, Hennekens CH, Willett WC: Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study. BMJ. 1998, 317 (7169): 1341-1345. 10.1136/bmj.317.7169.1341.CrossRefPubMedPubMedCentral
14.
go back to reference Gopinath B, Buyken AE, Flood VM, Empson M, Rochtchina E, Mitchell P: Consumption of polyunsaturated fatty acids, fish, and nuts and risk of inflammatory disease mortality. Am J Clin Nutr. 2011, 93 (5): 1073-1079. 10.3945/ajcn.110.009977.CrossRefPubMed Gopinath B, Buyken AE, Flood VM, Empson M, Rochtchina E, Mitchell P: Consumption of polyunsaturated fatty acids, fish, and nuts and risk of inflammatory disease mortality. Am J Clin Nutr. 2011, 93 (5): 1073-1079. 10.3945/ajcn.110.009977.CrossRefPubMed
Metadata
Title
Should we go nuts about nuts?
Authors
Sabine Rohrmann
David Faeh
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2013
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/1741-7015-11-165

Other articles of this Issue 1/2013

BMC Medicine 1/2013 Go to the issue