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BMC Gastroenterology
Published in: BMC Gastroenterology 1/2023

Open Access 01-12-2023 | Shock | Research

Clinical characteristics and risk factors of organ failure and death in necrotizing pancreatitis

Authors: Liqing Yu, Fengwen Xie, Lingyu Luo, Yupeng Lei, Xin Huang, Xiaoyu Yang, Yong Zhu, Cong He, Nianshuang Li, Wenhua He, Yin Zhu, Nonghua Lu, Bingjun Yu

Published in: BMC Gastroenterology | Issue 1/2023

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Abstract

Background

Organ failure (OF) and death are considered the most significant adverse outcomes in necrotizing pancreatitis (NP). However, there are few NP-related studies describing the clinical traits of OF and aggravated outcomes.

Purpose

An improved insight into the details of OF and death will be helpful to the management of NP. Thus, in our research, we addressed the risk factors of OF and death in NP patients.

Methods

We performed a study of 432 NP patients from May 2017 to December 2021. All patients with NP were followed up for 36 months. The primary end-points were risk factors of OF and death in NP patients. The risk factors were evaluated by logistic regression analysis.

Results

NP patients with OF or death patients were generally older, had a higher APACHE II score, longer hospital stay, longer ICU stay, as well as a higher incidence of severe acute pancreatitis (SAP), shock and pancreatic necrosis. Independent risk factors related to OF included BMI, APACHE II score and SAP (P < 0.05). Age, shock and APACHE II score (P < 0.05) were the most significant factors correlated with the risk of death in NP patients. Notably, increased mortality was linked to the number of failed organs.

Conclusions

NP is a potentially fatal disease with a long hospital or ICU stay. Our study indicated that the incidence of OF and death in NP patients was 69.9% and 10.2%, respectively. BMI, SAP, APACHE II score, age and shock are potential risk factors of OF and death in NP patients. Clinicians should focus on these factors for early diagnosis and appropriate therapy.
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Literature
1.
Krishna SG, Kamboj AK, Hart PA, Hinton A, Conwell DL. The changing epidemiology of acute pancreatitis hospitalizations: a decade of trends and the impact of chronic pancreatitis. Pancreas. 2017;46(4):482–8.CrossRef
2.
Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, Tsiotos GG, Vege SS. Acute Pancreatitis Classification Working G: Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62(1):102–11.CrossRef
3.
Mofidi R, Duff MD, Wigmore SJ, Madhavan KK, Garden OJ, Parks RW. Association between early systemic inflammatory response, severity of multiorgan dysfunction and death in acute pancreatitis. Br J Surg. 2006;93(6):738–44.CrossRef
4.
Buchler MW, Gloor B, Muller CA, Friess H, Seiler CA, Uhl W. Acute necrotizing pancreatitis: treatment strategy according to the status of infection. Ann Surg. 2000;232(5):619–26.CrossRef
5.
Bugiantella W, Rondelli F, Boni M, Stella P, Polistena A, Sanguinetti A, Avenia N. Necrotizing pancreatitis: A review of the interventions. Int J Surg. 2016;28(Suppl 1):S163-171.CrossRef
6.
Tenner S, Baillie J, DeWitt J, Vege SS, American College of G. American College of Gastroenterology guideline: management of acute pancreatitis. Am J Gastroenterol 2013;108(9):1400–15; 1416.
7.
Werner J, Hartwig W, Hackert T, Buchler MW. Surgery in the treatment of acute pancreatitis—open pancreatic necrosectomy. Scand J Surg. 2005;94(2):130–4.CrossRef
8.
Petrov MS, Shanbhag S, Chakraborty M, Phillips AR, Windsor JA. Organ failure and infection of pancreatic necrosis as determinants of mortality in patients with acute pancreatitis. Gastroenterology. 2010;139(3):813–20.CrossRef
9.
Boumitri C, Brown E, Kahaleh M. Necrotizing pancreatitis: current management and therapies. Clin Endosc. 2017;50(4):357–65.CrossRef
10.
Schepers NJ, Bakker OJ, Besselink MG, Ahmed Ali U, Bollen TL, Gooszen HG, van Santvoort HC, Bruno MJ. Dutch Pancreatitis Study G: impact of characteristics of organ failure and infected necrosis on mortality in necrotising pancreatitis. Gut. 2019;68(6):1044–51.CrossRef
11.
van Brunschot S, Hollemans RA, Bakker OJ, Besselink MG, Baron TH, Beger HG, Boermeester MA, Bollen TL, Bruno MJ, Carter R, et al. Minimally invasive and endoscopic versus open necrosectomy for necrotising pancreatitis: a pooled analysis of individual data for 1980 patients. Gut. 2018;67(4):697–706.
12.
Nesvaderani M, Eslick GD, Cox MR. Acute pancreatitis: update on management. Med J Aust. 2015;202(8):420–3.CrossRef
13.
Rasch S, Phillip V, Reichel S, Rau B, Zapf C, Rosendahl J, Halm U, Zachaus M, Muller M, Kleger A, et al. Open surgical versus minimal invasive necrosectomy of the pancreas-A retrospective multicenter analysis of the German pancreatitis study group. PLoS ONE. 2016;11(9):e0163651.CrossRef
14.
Facciorusso A, Amato A, Crino SF, Sinagra E, Maida M, Fugazza A, Binda C, Coluccio C, Repici A, Anderloni A, et al. Definition of a hospital volume threshold to optimize outcomes after drainage of pancreatic fluid collections with lumen-apposing metal stents: a nationwide cohort study. Gastrointest Endosc. 2022;95(6):1158–72.CrossRef
15.
Amato A, Tarantino I, Facciorusso A, Binda C, Crino SF, Fugazza A, Forti E, Petrone MC, Di Mitri R, Macchiarelli R, et al. Real-life multicentre study of lumen-apposing metal stent for EUS-guided drainage of pancreatic fluid collections. Gut. 2022;71(6):1050–2.CrossRef
16.
Werner J, Feuerbach S, Uhl W, Buchler MW. Management of acute pancreatitis: from surgery to interventional intensive care. Gut. 2005;54(3):426–36.CrossRef
17.
Wang S, Feng X, Li S, Liu C, Xu B, Bai B, Yu P, Feng Q, Zhao Q. The ability of current scoring systems in differentiating transient and persistent organ failure in patients with acute pancreatitis. J Crit Care. 2014;29(4):693 e697–611.
18.
Johnson CD, Abu-Hilal M. Persistent organ failure during the first week as a marker of fatal outcome in acute pancreatitis. Gut. 2004;53(9):1340–4.CrossRef
19.
Wu H, Li J, Zhao J, Li S. A new scoring system can be applied to predict the organ failure related events in acute pancreatitis accurately and rapidly. Pancreatology. 2020;20(4):622–8.CrossRef
20.
Garg PK, Singh VP. Organ failure due to systemic injury in acute pancreatitis. Gastroenterology. 2019;156(7):2008–23.CrossRef
21.
Mole DJ, Olabi B, Robinson V, Garden OJ, Parks RW. Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records. HPB (Oxford). 2009;11(2):166–70.CrossRef
22.
Wig JD, Bharathy KG, Kochhar R, Yadav TD, Kudari AK, Doley RP, Gupta V, Babu YR. Correlates of organ failure in severe acute pancreatitis. JOP. 2009;10(3):271–5.
23.
Sharma M, Banerjee D, Garg PK. Characterization of newer subgroups of fulminant and subfulminant pancreatitis associated with a high early mortality. Am J Gastroenterol. 2007;102(12):2688–95.CrossRef
24.
Choi JH, Kim MH, Cho DH, Oh D, Lee HW, Song TJ, Park DH, Lee SS, Seo DW, Lee SK. Revised Atlanta classification and determinant-based classification: which one better at stratifying outcomes of patients with acute pancreatitis? Pancreatology. 2017;17(2):194–200.CrossRef
25.
Garg PK, Madan K, Pande GK, Khanna S, Sathyanarayan G, Bohidar NP, Tandon RK. Association of extent and infection of pancreatic necrosis with organ failure and death in acute necrotizing pancreatitis. Clin Gastroenterol Hepatol. 2005;3(2):159–66.CrossRef
26.
Isenmann R, Rau B, Beger HG. Bacterial infection and extent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis. Br J Surg. 1999;86(8):1020–4.CrossRef
27.
Tenner S, Sica G, Hughes M, Noordhoek E, Feng S, Zinner M, Banks PA. Relationship of necrosis to organ failure in severe acute pancreatitis. Gastroenterology. 1997;113(3):899–903.CrossRef
28.
Lankisch PG, Pflichthofer D, Lehnick D. No strict correlation between necrosis and organ failure in acute pancreatitis. Pancreas. 2000;20(3):319–22.CrossRef
29.
Yu B, Li N, Li J, Wan J, He W, Zhu Y, Lu N. The clinical characteristics of acute pancreatitis in gerontal patients: a retrospective study. Clin Interv Aging. 2020;15:1541–53.CrossRef
30.
Baron TH, Morgan DE. Acute necrotizing pancreatitis. N Engl J Med. 1999;340(18):1412–7.CrossRef
31.
Trikudanathan G, Wolbrink DRJ, van Santvoort HC, Mallery S, Freeman M, Besselink MG. Current concepts in severe acute and necrotizing pancreatitis: an evidence-based approach. Gastroenterology. 2019;156(7):1994–2007 e1993.
32.
Boxhoorn L, Voermans RP, Bouwense SA, Bruno MJ, Verdonk RC, Boermeester MA, van Santvoort HC, Besselink MG. Acute pancreatitis. Lancet. 2020;396(10252):726–34.CrossRef
33.
Dellinger EP, Forsmark CE, Layer P, Levy P, Maravi-Poma E, Petrov MS, Shimosegawa T, Siriwardena AK, Uomo G, Whitcomb DC, et al. Determinant-based classification of acute pancreatitis severity: an international multidisciplinary consultation. Ann Surg. 2012;256(6):875–80.CrossRef
34.
Shen D, Wei Q, Huang H, Ning C, Li J, Chen L, Zhu S, Huang G. Synchronous organ failure and infected pancreatic necrosis define genuine critical acute pancreatitis. Dig Liver Dis. 2021;53(12):1590–5.CrossRef
35.
Minami K, Horibe M, Sanui M, Sasaki M, Iwasaki E, Sawano H, Goto T, Ikeura T, Takeda T, Oda T, et al. The effect of an invasive strategy for treating pancreatic necrosis on mortality: a retrospective multicenter cohort study. J Gastrointest Surg. 2020;24(9):2037–45.CrossRef
36.
Starr ME, Ueda J, Yamamoto S, Evers BM, Saito H. The effects of aging on pulmonary oxidative damage, protein nitration, and extracellular superoxide dismutase down-regulation during systemic inflammation. Free Radic Biol Med. 2011;50(2):371–80.CrossRef
37.
Fu S, Stanek A, Mueller CM, Brown NA, Huan C, Bluth MH, Zenilman ME. Acute pancreatitis in aging animals: loss of pancreatitis-associated protein protection? World J Gastroenterol. 2012;18(26):3379–88.CrossRef
38.
Turnbull IR, Clark AT, Stromberg PE, Dixon DJ, Woolsey CA, Davis CG, Hotchkiss RS, Buchman TG, Coopersmith CM. Effects of aging on the immunopathologic response to sepsis. Crit Care Med. 2009;37(3):1018–23.CrossRef
39.
40.
Ocobock C, Soppela P, Turunen MT. No association of BMI and body adiposity with cardiometabolic biomarkers among a small sample of reindeer herders of sub-Arctic Finland. Int J Circumpolar Health. 2022;81(1):2024960.CrossRef
41.
Ince AT, Seven G, Kochan K, Kiremitci S, Yildiz K, Senturk H. The course of acute pancreatitis in patients with different BMI groups. Pancreatology. 2022;22(3):348–55.CrossRef
42.
Wang SQ, Li SJ, Feng QX, Feng XY, Xu L, Zhao QC. Overweight is an additional prognostic factor in acute pancreatitis: a meta-analysis. Pancreatology. 2011;11(2):92–8.CrossRef
43.
Hong S, Qiwen B, Ying J, Wei A, Chaoyang T. Body mass index and the risk and prognosis of acute pancreatitis: a meta-analysis. Eur J Gastroenterol Hepatol. 2011;23(12):1136–43.CrossRef
44.
Johnson CD, Toh SK, Campbell MJ. Combination of APACHE-II score and an obesity score (APACHE-O) for the prediction of severe acute pancreatitis. Pancreatology. 2004;4(1):1–6.CrossRef
45.
Patel K, Trivedi RN, Durgampudi C, Noel P, Cline RA, DeLany JP, Navina S, Singh VP. Lipolysis of visceral adipocyte triglyceride by pancreatic lipases converts mild acute pancreatitis to severe pancreatitis independent of necrosis and inflammation. Am J Pathol. 2015;185(3):808–19.CrossRef
46.
Dai P, Qin X, Yan J, Cao F, Gao C, Wang X, Liu D, Li F. Predicting infected pancreatic necrosis based on influential factors among the most common types of acute pancreatitis: a retrospective cohort study. Ann Palliat Med. 2021;10(11):11745–55.CrossRef
47.
Zhou BM, Qiu ZL, Niu KX, Wang YE, Jie FC. Construction of a Nomogram Model for Predicting Pleural Effusion Secondary to Severe Acute Pancreatitis. Emerg Med Int. 2022;2022:4199209.CrossRef
48.
Malik AM. Biliary pancreatitis. Deadly threat to the elderly. Is it a real threat? Int J Health Sci (Qassim). 2015;9(1):35–9.
49.
Yadav D, Lowenfels AB. The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology. 2013;144(6):1252–61.CrossRef
50.
Jin M, Bai X, Chen X, Zhang H, Lu B, Li Y, Lai Y, Qian J, Yang H. A 16-year trend of etiology in acute pancreatitis: The increasing proportion of hypertriglyceridemia-associated acute pancreatitis and its adverse effect on prognosis. J Clin Lipidol. 2019;13(6):947–53 e941.
51.
Mosztbacher D, Hanak L, Farkas N, Szentesi A, Miko A, Bajor J, Sarlos P, Czimmer J, Vincze A, Hegyi PJ, et al. Hypertriglyceridemia-induced acute pancreatitis: a prospective, multicenter, international cohort analysis of 716 acute pancreatitis cases. Pancreatology. 2020;20(4):608–16.CrossRef
52.
Pascual I, Sanahuja A, Garcia N, Vazquez P, Moreno O, Tosca J, Pena A, Garayoa A, Lluch P, Mora F. Association of elevated serum triglyceride levels with a more severe course of acute pancreatitis: cohort analysis of 1457 patients. Pancreatology. 2019;19(5):623–9.CrossRef
53.
Li X, Ke L, Dong J, Ye B, Meng L, Mao W, Yang Q, Li W, Li J. Significantly different clinical features between hypertriglyceridemia and biliary acute pancreatitis: a retrospective study of 730 patients from a tertiary center. BMC Gastroenterol. 2018;18(1):89.CrossRef
54.
Nawaz H, Koutroumpakis E, Easler J, Slivka A, Whitcomb DC, Singh VP, Yadav D, Papachristou GI. Elevated serum triglycerides are independently associated with persistent organ failure in acute pancreatitis. Am J Gastroenterol. 2015;110(10):1497–503.CrossRef
55.
Yang AL, McNabb-Baltar J. Hypertriglyceridemia and acute pancreatitis. Pancreatology. 2020;20(5):795–800.CrossRef
56.
de Pretis N, Amodio A, Frulloni L. Hypertriglyceridemic pancreatitis: epidemiology, pathophysiology and clinical management. United Eur Gastroenterol J. 2018;6(5):649–55.CrossRef
57.
Valdivielso P, Ramirez-Bueno A, Ewald N. Current knowledge of hypertriglyceridemic pancreatitis. Eur J Intern Med. 2014;25(8):689–94.CrossRef
58.
Maatman TK, Westfall-Snyder JA, Ceppa EP, House MG, Nakeeb A, Nguyen TK, Schmidt CM, Zyromski NJ. Necrotizing pancreatitis from hypertriglyceridemia: more severe disease? Dig Dis Sci. 2021;66(12):4485–91.CrossRef
59.
Elhence A, Mahapatra SJ, Madhusudhan KS, Jain S, Sethia R, Teja V, Vajpai T, Malla S, Aggarwal P, Pandey S, et al. Pancreatic hemorrhage contributes to late mortality in patients with acute necrotizing pancreatitis. Pancreatology. 2022;22(2):219–25.CrossRef
60.
Maatman TK, Nicolas ME, Roch AM, Lewellen KA, Al-Azzawi HH, Ceppa EP, House MG, Nakeeb A, Schmidt CM, Zyromski NJ. Colon involvement in necrotizing pancreatitis: incidence, risk factors, and outcomes. Ann Surg. 2022;275(3):568–75.CrossRef
61.
Yang E, Nguyen NH, Kwong WT. Abdominal free fluid in acute pancreatitis predicts necrotizing pancreatitis and organ failure. Ann Gastroenterol. 2021;34(6):872–8.
62.
Trikudanathan G, Vantanasiri K, Faizi N, Munigala S, Vanek P, Schat R, Freeman ML, Chauhan A. Decreased skeletal muscle density is an independent predictor of mortality in necrotizing pancreatitis—a single tertiary center experience in 507 patients. Pancreatology. 2021;21:1146–51.CrossRef
63.
Fan ST, Choi TK, Lai CS, Wong J. Influence of age on the mortality from acute pancreatitis. Br J Surg. 1988;75(5):463–6.CrossRef
64.
Quero G, Covino M, Fiorillo C, Rosa F, Menghi R, Simeoni B, Potenza A, Ojetti V, Alfieri S, Franceschi F. Acute pancreatitis in elderly patients: a single-center retrospective evaluation of clinical outcomes. Scand J Gastroenterol. 2019;54(4):492–8.CrossRef
65.
Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–83.CrossRef
66.
Bang JY, Holt BA, Hawes RH, Hasan MK, Arnoletti JP, Christein JD, Wilcox CM, Varadarajulu S. Outcomes after implementing a tailored endoscopic step-up approach to walled-off necrosis in acute pancreatitis. Br J Surg. 2014;101(13):1729–38.CrossRef
67.
Sarathi Patra P, Das K, Bhattacharyya A, Ray S, Hembram J, Sanyal S, Dhali GK. Natural resolution or intervention for fluid collections in acute severe pancreatitis. Br J Surg. 2014;101(13):1721–8.CrossRef
68.
Banks PA, Freeman ML. Practice parameters Committee of the American College of G: practice guidelines in acute pancreatitis. Am J Gastroenterol. 2006;101(10):2379–400.CrossRef
69.
van Santvoort HC, Bakker OJ, Bollen TL, Besselink MG, Ahmed Ali U, Schrijver AM, Boermeester MA, van Goor H, Dejong CH, van Eijck CH, et al. A conservative and minimally invasive approach to necrotizing pancreatitis improves outcome. Gastroenterology. 2011;141(4):1254–63.CrossRef
70.
Sternby H, Bolado F, Canaval-Zuleta HJ, Marra-Lopez C, Hernando-Alonso AI, Del-Val-Antonana A, Garcia-Rayado G, Rivera-Irigoin R, Grau-Garcia FJ, Oms L, et al. Determinants of severity in acute pancreatitis: a nation-wide multicenter prospective cohort study. Ann Surg. 2019;270(2):348–55.CrossRef
71.
Dombernowsky T, Kristensen MO, Rysgaard S, Gluud LL, Novovic S. Risk factors for and impact of respiratory failure on mortality in the early phase of acute pancreatitis. Pancreatology. 2016;16(5):756–60.CrossRef
72.
De Troyer A, Naeije R, Yernault JC, Englert M. Impairment of pulmonary function in acute pancreatitis. Chest. 1978;73(3):360–3.CrossRef
73.
Pastor CM, Matthay MA, Frossard JL. Pancreatitis-associated acute lung injury: new insights. Chest. 2003;124(6):2341–51.CrossRef
74.
Force ADT, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS. Acute respiratory distress syndrome: the Berlin Definition. JAMA. 2012;307(23):2526–33.
75.
Singh AK, Samanta J, Shukla J, Birda CL, Dhar J, Gupta P, Kumar MP, Gupta V, Yadav TD, Sinha SK, et al. Impact of different patterns of organ failure on mortality in acute necrotizing pancreatitis. Pancreas. 2021;50(7):1030–6.CrossRef
76.
Shi N, Liu T, de la Iglesia-Garcia D, Deng L, Jin T, Lan L, Zhu P, Hu W, Zhou Z, Singh V, et al. Duration of organ failure impacts mortality in acute pancreatitis. Gut. 2020;69(3):604–5.CrossRef
Metadata
Title
Clinical characteristics and risk factors of organ failure and death in necrotizing pancreatitis
Authors
Liqing Yu
Fengwen Xie
Lingyu Luo
Yupeng Lei
Xin Huang
Xiaoyu Yang
Yong Zhu
Cong He
Nianshuang Li
Wenhua He
Yin Zhu
Nonghua Lu
Bingjun Yu
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2023
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/s12876-023-02651-4

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