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BMC Infectious Diseases
Published in: BMC Infectious Diseases 1/2018

Open Access 01-12-2018 | Case report

Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature

Authors: Kiwamu Nakamura, Kyoichi Saito, Yasuka Hara, Tetsuji Aoyagi, Kadzuhiro Kitakawa, Yoshinobu Abe, Hiromu Takemura, Fumihito Ikeda, Mitsuo Kaku, Keiji Kanemitsu

Published in: BMC Infectious Diseases | Issue 1/2018

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Abstract

Background

Human parechovirus type 3 (HPeV-3) is known to cause cold-like symptoms, diarrhea, or severe infections such as sepsis in infants and children. In adults, HPeV-3 infection is rarely diagnosed because the symptoms are generally mild and self-limiting; however, this infection has been linked to epidemic myalgia, regardless of the presence of underlying diseases, immunosuppression, or sex.

Case presentation

We describe an adult case of severe systemic myalgia and orchiodynia after infection with HPeV-3, which was transmitted from the child of the patient. Interleukin-6 (IL-6) level was found to be elevated in the patient’s serum.

Conclusion

Severe myalgia associated with HPeV-3 infection is potentially caused by an elevated serum level of IL-6.
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Metadata
Title
Severe epidemic myalgia with an elevated level of serum interleukin-6 caused by human parechovirus type 3: a case report and brief review of the literature
Authors
Kiwamu Nakamura
Kyoichi Saito
Yasuka Hara
Tetsuji Aoyagi
Kadzuhiro Kitakawa
Yoshinobu Abe
Hiromu Takemura
Fumihito Ikeda
Mitsuo Kaku
Keiji Kanemitsu
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2018
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-018-3284-5

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