Published in:
Open Access
01-06-2012 | Letter to the Editor
Serum AMH concentration as a marker evaluating gonadal function in boys operated on for unilateral cryptorchidism between 1st and 4th year of life—why patients with inguinal hernia served as controls
Authors:
Ewa Matuszczak, Adam Hermanowicz, Wojciech Debek
Published in:
Endocrine
|
Issue 3/2012
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Excerpt
In our study “Serum AMH concentration as a marker evaluating gonadal function in boys operated on for unilateral cryptorchidism between 1st and 4th year of life” [
1], we measured serum AMH (anti-Mullerian hormone) levels in boys with cryptorchidism and boys with inguinal hernia. AMH is secreted by immature Sertoli cells during the 8th week of gestation, and is responsible for the regression of Mullerian ducts in the male fetus as part of the sexual differentiation process. With the onset of puberty and spermatogenesis in healthy men, the secretion of AMH declines in correlation to the maturation of Sertoli cells. Only Sertoli cells remain active during childhood, so the evaluation of gonadal function in the prepubertal male relies on the assessment of Sertoli cell products [
2]. …
