Skip to main content
Top
Published in: Neurocritical Care 1/2022

08-02-2022 | Septicemia | Invited Commentary

Commentary on Posterior Reversible Encephalopathy Syndrome and Sepsis-Associated Encephalopathy

Author: G. Bryan Young

Published in: Neurocritical Care | Issue 1/2022

Login to get access

Excerpt

Posterior reversible encephalopathy syndrome (PRES), a clinical–radiological syndrome, was first described by Hinchey et al. [1] in 1996: an acute illness with headache, altered mental status, blindness (with reactive pupils), and seizures associated with vasogenic edema, usually without contrast enhancement, predominantly in the posterior cerebrum bilaterally. Other cerebral regions, the cerebellum and brainstem, were sometimes involved. Most patients were hypertensive, often with renal impairment, and some were on immunosuppressive drugs. The clinical and radiological features resolved with control of blood pressure or discontinuation of immunosuppressives. …
Literature
1.
go back to reference Hinchey J, Chaves C, Appignani B, et al. A reversible posterior leukoencephalopathy syndrome. N Eng J Med. 1996;33:484–500. Hinchey J, Chaves C, Appignani B, et al. A reversible posterior leukoencephalopathy syndrome. N Eng J Med. 1996;33:484–500.
2.
go back to reference Linman TG, Bohner G, Heuschmann M, et al. The clinical and radiological spectrum of posterior reversible encephalopathy syndrome: the retrospective Berlin PRES study. J Neurol. 2012;259:155–64.CrossRef Linman TG, Bohner G, Heuschmann M, et al. The clinical and radiological spectrum of posterior reversible encephalopathy syndrome: the retrospective Berlin PRES study. J Neurol. 2012;259:155–64.CrossRef
3.
go back to reference McKinney AM, Short J, Truwit CL, et al. Posterior reversible encephalopathy syndrome: incidence of atypical regions of involvement and imaging findings. Am J Roentgenol. 2007;189:904–12.CrossRef McKinney AM, Short J, Truwit CL, et al. Posterior reversible encephalopathy syndrome: incidence of atypical regions of involvement and imaging findings. Am J Roentgenol. 2007;189:904–12.CrossRef
4.
go back to reference Feske SK. Posterior reversible encephalopathy syndrome: a review. Semin Neurol. 2011;31:202–15.CrossRef Feske SK. Posterior reversible encephalopathy syndrome: a review. Semin Neurol. 2011;31:202–15.CrossRef
6.
go back to reference Gofton TE, Young GB. Sepsis-associated encephalopathy. Nat Rev Neurol. 2012;8:557–66.CrossRef Gofton TE, Young GB. Sepsis-associated encephalopathy. Nat Rev Neurol. 2012;8:557–66.CrossRef
7.
go back to reference Helbing DL, Böhm L, Witte OW. Sepsis-associated encephalopathy. CMAJ. 2018;190(36):E1083.CrossRef Helbing DL, Böhm L, Witte OW. Sepsis-associated encephalopathy. CMAJ. 2018;190(36):E1083.CrossRef
8.
go back to reference Blanco PJ, Müller LO, Spence JD. Blood pressure gradients in cerebral arteries: a clue to pathogenesis of cerebral small vessel disease. Stroke and Vasc Neurol. 2017;2:108–17.CrossRef Blanco PJ, Müller LO, Spence JD. Blood pressure gradients in cerebral arteries: a clue to pathogenesis of cerebral small vessel disease. Stroke and Vasc Neurol. 2017;2:108–17.CrossRef
9.
go back to reference Kadry H, Noorani B, Cucullo L. A blood-brain barrier overview on structure, function, impairment, and biomarkers of integrity. Fluids Barriers CNS. 2020;17:69.CrossRef Kadry H, Noorani B, Cucullo L. A blood-brain barrier overview on structure, function, impairment, and biomarkers of integrity. Fluids Barriers CNS. 2020;17:69.CrossRef
10.
go back to reference Riedemann NC, Guo RF, Ward PA. Novel strategies for the treatment of sepsis. Nat Med. 2003;9:517–24.CrossRef Riedemann NC, Guo RF, Ward PA. Novel strategies for the treatment of sepsis. Nat Med. 2003;9:517–24.CrossRef
Metadata
Title
Commentary on Posterior Reversible Encephalopathy Syndrome and Sepsis-Associated Encephalopathy
Author
G. Bryan Young
Publication date
08-02-2022
Publisher
Springer US
Published in
Neurocritical Care / Issue 1/2022
Print ISSN: 1541-6933
Electronic ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-022-01443-0

Other articles of this Issue 1/2022

Neurocritical Care 1/2022 Go to the issue