Skip to main content
Top
Published in: Pituitary 2/2012

01-06-2012

Sellar plasmacytomas: a concise review

Authors: Rene Joukhadar, Ken Chiu

Published in: Pituitary | Issue 2/2012

Login to get access

Abstract

The diagnosis of a sellar plasmacytoma is often missed and is mistaken for a non functioning pituitary adenoma. We reviewed the literature on reported cases of sellar plasmacytoma in order to identify its clinical presentation, laboratory, radiological and pathological characteristics. We describe the management of these cases after the correct diagnosis was made and provide insight to preoperative diagnosis of this entity. Preoperative diagnosis may help avoid unnecessary surgical resection of an otherwise radiosensitive tumor. We also report and describe in detail a new case of sellar plasmacytoma that we have recently evaluated.
Literature
1.
go back to reference Sanchez JA, Rahman S, Strauss RA, Kaye GI (1977) Multiple myeloma masquerading as a pituitary tumor. Arch Pathol Lab Med 101(1):55–56PubMed Sanchez JA, Rahman S, Strauss RA, Kaye GI (1977) Multiple myeloma masquerading as a pituitary tumor. Arch Pathol Lab Med 101(1):55–56PubMed
2.
go back to reference Poon MC, Prchal JT, Murad TM, Galbraith JG (1979) Multiple myeloma masquerading as chromophobe adenoma. Cancer 43(4):1513–1515PubMedCrossRef Poon MC, Prchal JT, Murad TM, Galbraith JG (1979) Multiple myeloma masquerading as chromophobe adenoma. Cancer 43(4):1513–1515PubMedCrossRef
3.
go back to reference Urbanski SJ, Bilbao JM, Horvath E, Kovacs K, So W, Ward JV (1980) Intrasellar solitary plasmacytoma terminating in multiple myeloma: a report of a case including electron microscopical study. Surg Neurol 14(3):233–236PubMed Urbanski SJ, Bilbao JM, Horvath E, Kovacs K, So W, Ward JV (1980) Intrasellar solitary plasmacytoma terminating in multiple myeloma: a report of a case including electron microscopical study. Surg Neurol 14(3):233–236PubMed
4.
go back to reference Vallat M, Vallat JM, Loubet A, Leboutet MJ, Robin A (1981) Plasmacytoma with pituitary localization. Report of a case. Bull Soc Ophtalmol Fr 81(3):355–356PubMed Vallat M, Vallat JM, Loubet A, Leboutet MJ, Robin A (1981) Plasmacytoma with pituitary localization. Report of a case. Bull Soc Ophtalmol Fr 81(3):355–356PubMed
5.
go back to reference Vaquero J, Areitio E, Martinez R (1982) Intracranial parasellar plasmacytoma. Arch Neurol 39(11):738PubMedCrossRef Vaquero J, Areitio E, Martinez R (1982) Intracranial parasellar plasmacytoma. Arch Neurol 39(11):738PubMedCrossRef
6.
go back to reference Hornedo J, Calvo F, Aramburu P, Aragón G, de la Torre A, Arellano A, Otero J (1982) Extramedullary IgD lambda plasmacytoma mimicking a pituitary chromophobe adenoma. Med Clin (Barc) 79(8):377–379 Hornedo J, Calvo F, Aramburu P, Aragón G, de la Torre A, Arellano A, Otero J (1982) Extramedullary IgD lambda plasmacytoma mimicking a pituitary chromophobe adenoma. Med Clin (Barc) 79(8):377–379
7.
go back to reference Kerty E, Nakstad PH (1984) Plasmocytoma masquerading as a pituitary tumour. J Neurol Neurosurg Psychiatry 47(1):99–100PubMedCrossRef Kerty E, Nakstad PH (1984) Plasmocytoma masquerading as a pituitary tumour. J Neurol Neurosurg Psychiatry 47(1):99–100PubMedCrossRef
8.
go back to reference Evans PJ, Jones MK, Hall R, Scanlon MF (1985) Pituitary function with a solitary intrasellar plasmacytoma. Postgrad Med J 61(716):513–514PubMedCrossRef Evans PJ, Jones MK, Hall R, Scanlon MF (1985) Pituitary function with a solitary intrasellar plasmacytoma. Postgrad Med J 61(716):513–514PubMedCrossRef
9.
go back to reference Bitterman P, Ariza A, Black RA, Allen WE 3rd, Lee SH (1986) Multiple myeloma mimicking pituitary adenoma. Comput Radiol 10(4):201–205PubMedCrossRef Bitterman P, Ariza A, Black RA, Allen WE 3rd, Lee SH (1986) Multiple myeloma mimicking pituitary adenoma. Comput Radiol 10(4):201–205PubMedCrossRef
10.
go back to reference Harrison LB, Schnall S, Cardinale FS, Farber LR (1987) Multiple myeloma presenting as a pituitary tumor. Int J Radiat Oncol Biol Phys 13(4):653–654PubMedCrossRef Harrison LB, Schnall S, Cardinale FS, Farber LR (1987) Multiple myeloma presenting as a pituitary tumor. Int J Radiat Oncol Biol Phys 13(4):653–654PubMedCrossRef
11.
go back to reference Estopiñán V, Riobó P, Fernández G, Varela C (1987) Intrasellar plasmacytoma simulating a pituitary adenoma. Med Clin (Barc) 89(3):128 Estopiñán V, Riobó P, Fernández G, Varela C (1987) Intrasellar plasmacytoma simulating a pituitary adenoma. Med Clin (Barc) 89(3):128
12.
go back to reference Dhanani AN, Bilbao JM, Kovacs K (1990) Multiple myeloma presenting as a sellar plasmacytoma and mimicking a pituitary tumor: report of a case and a review of the literature. Endocr Pathol 1:245–248CrossRef Dhanani AN, Bilbao JM, Kovacs K (1990) Multiple myeloma presenting as a sellar plasmacytoma and mimicking a pituitary tumor: report of a case and a review of the literature. Endocr Pathol 1:245–248CrossRef
13.
go back to reference Jacquet G, Vuillier J, Viennet A, Godard J, Steimle R (1991) Solitary plasmacytoma simulating pituitary adenoma. Neurochirurgie 37(1):67–71PubMed Jacquet G, Vuillier J, Viennet A, Godard J, Steimle R (1991) Solitary plasmacytoma simulating pituitary adenoma. Neurochirurgie 37(1):67–71PubMed
14.
go back to reference Juneau P, Schoene WC, Black P (1992) Malignant tumors in the pituitary gland. Arch Neurol 49(5):555–558PubMedCrossRef Juneau P, Schoene WC, Black P (1992) Malignant tumors in the pituitary gland. Arch Neurol 49(5):555–558PubMedCrossRef
15.
go back to reference Losa M, Terreni MR, Tresoldi M, Marcatti M, Campi A, Triulzi F, Scotti G, Giovanelli M (1992) Solitary plasmacytoma of the sphenoid sinus involving the pituitary fossa: a case report and review of the literature. Surg Neurol 37(5):388–393PubMedCrossRef Losa M, Terreni MR, Tresoldi M, Marcatti M, Campi A, Triulzi F, Scotti G, Giovanelli M (1992) Solitary plasmacytoma of the sphenoid sinus involving the pituitary fossa: a case report and review of the literature. Surg Neurol 37(5):388–393PubMedCrossRef
16.
go back to reference Sautner D, Saeger W, Lüdecke DK (1993) Tumors of the sellar region mimicking pituitary adenomas. Exp Clin Endocrinol 101(5):283–289PubMedCrossRef Sautner D, Saeger W, Lüdecke DK (1993) Tumors of the sellar region mimicking pituitary adenomas. Exp Clin Endocrinol 101(5):283–289PubMedCrossRef
17.
go back to reference Smith MV, Laws ER Jr (1994) Magnetic resonance imaging measurements of pituitary stalk compression and deviation in patients with nonprolactin-secreting intrasellar and parasellar tumors: lack of correlation with serum prolactin levels. Neurosurgery 34(5):834–839PubMedCrossRef Smith MV, Laws ER Jr (1994) Magnetic resonance imaging measurements of pituitary stalk compression and deviation in patients with nonprolactin-secreting intrasellar and parasellar tumors: lack of correlation with serum prolactin levels. Neurosurgery 34(5):834–839PubMedCrossRef
18.
go back to reference Bindal AK, Bindal RK, van Loveren H, Sawaya R (1995) Management of intracranial plasmacytoma. J Neurosurg 83(2):218–221PubMedCrossRef Bindal AK, Bindal RK, van Loveren H, Sawaya R (1995) Management of intracranial plasmacytoma. J Neurosurg 83(2):218–221PubMedCrossRef
19.
go back to reference Kanoh T, Okuda T, Hayashi M, Yumoto Y (1996) Multiple myeloma presenting as parasellar syndrome and cranial nerve palsies. Rinsho Ketsueki 37(3):260–264PubMed Kanoh T, Okuda T, Hayashi M, Yumoto Y (1996) Multiple myeloma presenting as parasellar syndrome and cranial nerve palsies. Rinsho Ketsueki 37(3):260–264PubMed
20.
go back to reference Mandagere KA, Schimke RN, Kyner JL, Bhatia PS (1998) An unusual sellar mass—solitary plasmacytoma. Endocr Pract 4(6):382–386PubMed Mandagere KA, Schimke RN, Kyner JL, Bhatia PS (1998) An unusual sellar mass—solitary plasmacytoma. Endocr Pract 4(6):382–386PubMed
21.
go back to reference Weber J, Jaksche H (1999) Solitary plasmacytoma of the pituitary area. Acta Neurochir (Wien) 141(2):219–220CrossRef Weber J, Jaksche H (1999) Solitary plasmacytoma of the pituitary area. Acta Neurochir (Wien) 141(2):219–220CrossRef
22.
go back to reference Weilbaecher C, Patwardhan RV, Fowler M, Willis BK, Nanda A (2004) Metastatic lesions involving the sella: report of three cases and review of the literature. Neurol India 52(3):365–368PubMed Weilbaecher C, Patwardhan RV, Fowler M, Willis BK, Nanda A (2004) Metastatic lesions involving the sella: report of three cases and review of the literature. Neurol India 52(3):365–368PubMed
23.
go back to reference McLaughlin DM, Gray WJ, Jones FG, Mirakhur M, McCance DR, Sheridan B, Atkinson AB (2004) Plasmacytoma: an unusual cause of a pituitary mass lesion. A case report and a review of the literature. Pituitary 7(3):179–181PubMedCrossRef McLaughlin DM, Gray WJ, Jones FG, Mirakhur M, McCance DR, Sheridan B, Atkinson AB (2004) Plasmacytoma: an unusual cause of a pituitary mass lesion. A case report and a review of the literature. Pituitary 7(3):179–181PubMedCrossRef
24.
go back to reference Oishi T, Kasai H, Sakurai Y, Kawamoto K (2006) Extramedullary plasmacytoma extensively affecting the sella turcica and paranasal sinuses. Clin Neuropathol 25(1):44–47PubMed Oishi T, Kasai H, Sakurai Y, Kawamoto K (2006) Extramedullary plasmacytoma extensively affecting the sella turcica and paranasal sinuses. Clin Neuropathol 25(1):44–47PubMed
25.
go back to reference Sinnott BP, Hatipoglu B, Sarne DH (2006) Intrasellar plasmacytoma presenting as a non-functional invasive pituitary macro-adenoma: case report & literature review. Pituitary 9(1):65–72PubMedCrossRef Sinnott BP, Hatipoglu B, Sarne DH (2006) Intrasellar plasmacytoma presenting as a non-functional invasive pituitary macro-adenoma: case report & literature review. Pituitary 9(1):65–72PubMedCrossRef
26.
go back to reference Pamir MN, Kilic T, Ozek MM, Ozduman K, Türe U (2006) Non-meningeal tumours of the cavernous sinus: a surgical analysis. J Clin Neurosci 13(6):626–635PubMedCrossRef Pamir MN, Kilic T, Ozek MM, Ozduman K, Türe U (2006) Non-meningeal tumours of the cavernous sinus: a surgical analysis. J Clin Neurosci 13(6):626–635PubMedCrossRef
27.
go back to reference Pitini V, Arrigo C, Alafaci C, Altavilla G (2008) Extramedullary plasmacytoma presented as a non-functional invasive pituitary macro-adenoma. J Neurooncol 88(2):227–229PubMedCrossRef Pitini V, Arrigo C, Alafaci C, Altavilla G (2008) Extramedullary plasmacytoma presented as a non-functional invasive pituitary macro-adenoma. J Neurooncol 88(2):227–229PubMedCrossRef
28.
go back to reference Yaman E, Benekli M, Coskun U, Sezer K, Ozturk B, Kaya AO, Yildiz R, Uluoglu O, Buyukberber S (2008) Intrasellar plasmacytoma: an unusual presentation of multiple myeloma. Acta Neurochir (Wien) 150(9):921–924CrossRef Yaman E, Benekli M, Coskun U, Sezer K, Ozturk B, Kaya AO, Yildiz R, Uluoglu O, Buyukberber S (2008) Intrasellar plasmacytoma: an unusual presentation of multiple myeloma. Acta Neurochir (Wien) 150(9):921–924CrossRef
29.
go back to reference Ceylan S, Koc K, Anik I (2009) Extended endoscopic approaches for midline skull-base lesions. Neurosurg Rev 32(3):309–319PubMedCrossRef Ceylan S, Koc K, Anik I (2009) Extended endoscopic approaches for midline skull-base lesions. Neurosurg Rev 32(3):309–319PubMedCrossRef
30.
go back to reference Rivera J, Alves S, Bianchi CC, Al-Mutawa N, Guiot MC, Zeitouni A (2010) An unusual collision tumor comprising a prolactinoma and a plasmocytoma originating from the sellar region. Pituitary 13(2):189–193PubMedCrossRef Rivera J, Alves S, Bianchi CC, Al-Mutawa N, Guiot MC, Zeitouni A (2010) An unusual collision tumor comprising a prolactinoma and a plasmocytoma originating from the sellar region. Pituitary 13(2):189–193PubMedCrossRef
31.
go back to reference Azarpira N, Vasei M, Rasekhi A (2011) Plasma cell tumors with neurologic symptoms: cytological findings. Diagn Cytopathol. doi:10.1002/dc.21623 Azarpira N, Vasei M, Rasekhi A (2011) Plasma cell tumors with neurologic symptoms: cytological findings. Diagn Cytopathol. doi:10.​1002/​dc.​21623
32.
go back to reference McComb DJ, Kovacs K, Beri J, Zak F (1984) Pituitary adenomas in old Sprague-Dawley rats: a histologic, ultrastructural, and immunocytochemical study. J Natl Cancer Inst 73(5):1143–1166PubMed McComb DJ, Kovacs K, Beri J, Zak F (1984) Pituitary adenomas in old Sprague-Dawley rats: a histologic, ultrastructural, and immunocytochemical study. J Natl Cancer Inst 73(5):1143–1166PubMed
33.
go back to reference Freda PU, Wardlaw SL, Post KD (1996) Unusual causes of sellar/parasellar masses in a large transsphenoidal surgical series. J Clin Endocrinol Metab 81(10):3455–3459PubMedCrossRef Freda PU, Wardlaw SL, Post KD (1996) Unusual causes of sellar/parasellar masses in a large transsphenoidal surgical series. J Clin Endocrinol Metab 81(10):3455–3459PubMedCrossRef
34.
go back to reference Kyle RA, Gertz MA, Witzig TE, Lust JA, Lacy MQ, Dispenzieri A, Fonseca R, Rajkumar SV, Offord JR, Larson DR, Plevak ME, Therneau TM, Greipp PR (2003) Review of 1027 patients with newly diagnosed multiple myeloma. Mayo Clin Proc 78(1):21PubMedCrossRef Kyle RA, Gertz MA, Witzig TE, Lust JA, Lacy MQ, Dispenzieri A, Fonseca R, Rajkumar SV, Offord JR, Larson DR, Plevak ME, Therneau TM, Greipp PR (2003) Review of 1027 patients with newly diagnosed multiple myeloma. Mayo Clin Proc 78(1):21PubMedCrossRef
35.
go back to reference Soutar R, Lucraft H, Jackson G, Reece A, Bird J, Low E, Samson D (2004) Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haematol 124(6):717PubMedCrossRef Soutar R, Lucraft H, Jackson G, Reece A, Bird J, Low E, Samson D (2004) Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haematol 124(6):717PubMedCrossRef
37.
go back to reference Freda PU, Post KD (1999) Differential diagnosis of sellar masses. Endocrinol Metab Clin North Am 28(1):81PubMedCrossRef Freda PU, Post KD (1999) Differential diagnosis of sellar masses. Endocrinol Metab Clin North Am 28(1):81PubMedCrossRef
38.
go back to reference Saeger W, Lüdecke DK, Buchfelder M, Fahlbusch R, Quabbe HJ, Petersenn S (2007) Pathohistological classification of pituitary tumors: 10 years of experience with the German pituitary tumor registry. Eur J Endocrinol 156(2):203PubMedCrossRef Saeger W, Lüdecke DK, Buchfelder M, Fahlbusch R, Quabbe HJ, Petersenn S (2007) Pathohistological classification of pituitary tumors: 10 years of experience with the German pituitary tumor registry. Eur J Endocrinol 156(2):203PubMedCrossRef
39.
go back to reference Tournier-Rangeard L, Lapeyre M, Graff-Caillaud P, Mege A, Dolivet G, Toussaint B, Charra-Brunaud C, Hoffstetter S, Marchal C, Peiffert D (2006) Radiotherapy for solitary extramedullary plasmacytoma in the head-and-neck region: a dose greater than 45 Gy to the target volume improves the local control. Int J Radiat Oncol Biol Phys 64(4):1013PubMedCrossRef Tournier-Rangeard L, Lapeyre M, Graff-Caillaud P, Mege A, Dolivet G, Toussaint B, Charra-Brunaud C, Hoffstetter S, Marchal C, Peiffert D (2006) Radiotherapy for solitary extramedullary plasmacytoma in the head-and-neck region: a dose greater than 45 Gy to the target volume improves the local control. Int J Radiat Oncol Biol Phys 64(4):1013PubMedCrossRef
40.
go back to reference Creach KM, Foote RL, Neben-Wittich MA, Kyle RA (2009) Radiotherapy for extramedullary plasmacytoma of the head and neck. Int J Radiat Oncol Biol Phys 73(3):789PubMedCrossRef Creach KM, Foote RL, Neben-Wittich MA, Kyle RA (2009) Radiotherapy for extramedullary plasmacytoma of the head and neck. Int J Radiat Oncol Biol Phys 73(3):789PubMedCrossRef
Metadata
Title
Sellar plasmacytomas: a concise review
Authors
Rene Joukhadar
Ken Chiu
Publication date
01-06-2012
Publisher
Springer US
Published in
Pituitary / Issue 2/2012
Print ISSN: 1386-341X
Electronic ISSN: 1573-7403
DOI
https://doi.org/10.1007/s11102-011-0352-x

Other articles of this Issue 2/2012

Pituitary 2/2012 Go to the issue
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.