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Published in: World Journal of Surgical Oncology 1/2017

Open Access 01-12-2017 | Case Report

Sclerosing mesenteritis mimicking metachronous peritoneal metastases from descending colon adenocarcinoma

Authors: Toshifumi Watanabe, Shiro Terai, Tomoya Tsukada, Masaki Takeshita, Koshi Matsui, Koji Amaya, Masahide Kaji, Kiichi Maeda, Koichi Shimizu, Junko Saito, Kentaro Mochizuki, Akio Uchiyama

Published in: World Journal of Surgical Oncology | Issue 1/2017

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Abstract

Background

Sclerosing mesenteritis is a non-neoplastic inflammatory disease that occurs in the bowel mesentery. Distinguishing sclerosing mesenteritis from neoplasms may be difficult because of the clinical and radiographic similarities between the two disease entities.

Case presentation

We report a case of sclerosing mesenteritis mimicking peritoneal metastases of colorectal carcinoma. A 73-year-old man with stage II descending colon adenocarcinoma with poor prognostic features was found to have developed left lower abdominal quadrant masses on computed tomography (CT) 9 months after undergoing radical surgery. These masses were diagnosed as peritoneal metastases because they grew in size and displayed fluorodeoxyglucose (FDG) uptake 3 months later; thus, a laparotomy was performed. The masses, which were localized in the jejunal mesentery, were excised completely via segmental jejunal resection. Histopathological analysis confirmed that the masses were sclerosing mesenteritis. The patient showed no signs of sclerosing mesenteritis or colorectal carcinoma recurrence during follow-up.

Conclusions

In patients suspected of having localized peritoneal metastasis from malignancies, any masses must be sampled by surgical excisional biopsy and subsequently examined to rule out alternative diagnoses, such as sclerosing mesenteritis.
Literature
1.
go back to reference Emory TS, Monihan JM, Carr NJ, Sobin LH. Sclerosing mesenteritis, mesenteric panniculitis and mesenteric lipodystrophy: a single entity? Am J Surg Pathol. 1997;21:392–8.CrossRefPubMed Emory TS, Monihan JM, Carr NJ, Sobin LH. Sclerosing mesenteritis, mesenteric panniculitis and mesenteric lipodystrophy: a single entity? Am J Surg Pathol. 1997;21:392–8.CrossRefPubMed
2.
go back to reference Sabate JM, Torrubia S, Maideu J, Franquet T, Monill JM, Perez C. Sclerosing mesenteritis: imaging findings in 17 patients. AJR Am J Roentgenol. 1999;172:625–9.CrossRefPubMed Sabate JM, Torrubia S, Maideu J, Franquet T, Monill JM, Perez C. Sclerosing mesenteritis: imaging findings in 17 patients. AJR Am J Roentgenol. 1999;172:625–9.CrossRefPubMed
3.
go back to reference Akram S, Pardi DS, Schaffner JA, Smyrk TC. Sclerosing mesenteritis: clinical features, treatment, and outcome in ninety-two patients. Clin Gastroenterol Hepatol. 2007;5:589–96.CrossRefPubMed Akram S, Pardi DS, Schaffner JA, Smyrk TC. Sclerosing mesenteritis: clinical features, treatment, and outcome in ninety-two patients. Clin Gastroenterol Hepatol. 2007;5:589–96.CrossRefPubMed
4.
go back to reference Nobili C, Degrate L, Caprotti R, Franciosi C, Leone BE, Romano F, Dinelli M, Uggeri F. Extensive sclerosing mesenteritis of the rectosigmoid colon associated with erosive colitis. Gastroenterol Res Pract 2009; doi: 10.1155/2009/176793. Nobili C, Degrate L, Caprotti R, Franciosi C, Leone BE, Romano F, Dinelli M, Uggeri F. Extensive sclerosing mesenteritis of the rectosigmoid colon associated with erosive colitis. Gastroenterol Res Pract 2009; doi: 10.​1155/​2009/​176793.
5.
go back to reference Duman M, Kocak O, Fazli O, Kocak C, Atici AE, Duman U. Mesenteric panniculitis patients requiring emergency surgery: report of three cases. Turk J Gastroenterol. 2012;23:181–4.CrossRefPubMed Duman M, Kocak O, Fazli O, Kocak C, Atici AE, Duman U. Mesenteric panniculitis patients requiring emergency surgery: report of three cases. Turk J Gastroenterol. 2012;23:181–4.CrossRefPubMed
6.
go back to reference Scudiere JR, Shi C, Hruban RH, Herman JM, Fishman EK, Schulick RD, Wolfgang CL, Makary MA, Thornton K, Montgomery E, Horton KM. Sclerosing mesenteritis involving the pancreas: a mimicker of pancreatic cancer. Am J Surg Pathol. 2010;34:447–53.CrossRefPubMedPubMedCentral Scudiere JR, Shi C, Hruban RH, Herman JM, Fishman EK, Schulick RD, Wolfgang CL, Makary MA, Thornton K, Montgomery E, Horton KM. Sclerosing mesenteritis involving the pancreas: a mimicker of pancreatic cancer. Am J Surg Pathol. 2010;34:447–53.CrossRefPubMedPubMedCentral
7.
go back to reference Tierney C, Dinkelspiel HE, Bass AR, Cimic A, Katzen J, Holcomb K. Sclerosing mesenteritis mimics gynecologic malignancy. Gynecol Oncol Rep. 2015;12:49–51.CrossRefPubMedPubMedCentral Tierney C, Dinkelspiel HE, Bass AR, Cimic A, Katzen J, Holcomb K. Sclerosing mesenteritis mimics gynecologic malignancy. Gynecol Oncol Rep. 2015;12:49–51.CrossRefPubMedPubMedCentral
8.
go back to reference He H, Zhi M, Zhang M, Su M, Chen H, Kang L, Huang Y, Zhou Z, Gao X, Wang J, Hu P. Sclerosing mesenteritis: multidisciplinary collaboration is essential for diagnosis and treatment. Gastroenterology Res. 2017;10:50–5.CrossRefPubMedPubMedCentral He H, Zhi M, Zhang M, Su M, Chen H, Kang L, Huang Y, Zhou Z, Gao X, Wang J, Hu P. Sclerosing mesenteritis: multidisciplinary collaboration is essential for diagnosis and treatment. Gastroenterology Res. 2017;10:50–5.CrossRefPubMedPubMedCentral
9.
go back to reference Rincon JO, Regi AR, Hualde AM, Berenguer LR, Moreno LH, Farto JCA. A prospective study to determine the real value of mesenteric 18F-FDG uptake in cancer patients. Inflammatory or tumoral mesenteric paniculitis? Rev Esp Med Nucl Imagen Mol. 2014;33:352–7. Rincon JO, Regi AR, Hualde AM, Berenguer LR, Moreno LH, Farto JCA. A prospective study to determine the real value of mesenteric 18F-FDG uptake in cancer patients. Inflammatory or tumoral mesenteric paniculitis? Rev Esp Med Nucl Imagen Mol. 2014;33:352–7.
11.
go back to reference Daskalogiannaki M, Voloudaki A, Prassopoulos P, Magkanas E, Stefanaki K, Apostolaki E, Gourtsoyiannis N. CT evaluation of mesenteric panniculitis: prevalence and associated diseases. AJR Am J Roentgenol. 2000;174:427–31.CrossRefPubMed Daskalogiannaki M, Voloudaki A, Prassopoulos P, Magkanas E, Stefanaki K, Apostolaki E, Gourtsoyiannis N. CT evaluation of mesenteric panniculitis: prevalence and associated diseases. AJR Am J Roentgenol. 2000;174:427–31.CrossRefPubMed
13.
go back to reference Masulovic D, Jovanovic M, Ivanovic A, Stojakov D, Micev M, Stevic R, Filipovic A, Galun D. Sclerosing mesenteritis presenting as a pseudotumor of the greater omentum. Med Princ Pract. 2016;25:93–5.CrossRefPubMed Masulovic D, Jovanovic M, Ivanovic A, Stojakov D, Micev M, Stevic R, Filipovic A, Galun D. Sclerosing mesenteritis presenting as a pseudotumor of the greater omentum. Med Princ Pract. 2016;25:93–5.CrossRefPubMed
14.
go back to reference Ehrenpreis ED, Rao AS, Aki R, Brown H, Pae T, Boiskin I. Normal positron emission tomography-computerized tomogram in a patient with apparent mesenteric panniculitis: biopsy is still the answer. Case Rep Gastroenterol. 2009;3:131–7.CrossRefPubMedPubMedCentral Ehrenpreis ED, Rao AS, Aki R, Brown H, Pae T, Boiskin I. Normal positron emission tomography-computerized tomogram in a patient with apparent mesenteric panniculitis: biopsy is still the answer. Case Rep Gastroenterol. 2009;3:131–7.CrossRefPubMedPubMedCentral
15.
go back to reference Apostolakis S, Ioannidis A, Tsioga G, Papageorgiou K, Velimezis G. A systematic investigation of sclerosing mesenteritis through CT and MRI. Radiol Case Rep. 2016;11:299–302.CrossRefPubMedPubMedCentral Apostolakis S, Ioannidis A, Tsioga G, Papageorgiou K, Velimezis G. A systematic investigation of sclerosing mesenteritis through CT and MRI. Radiol Case Rep. 2016;11:299–302.CrossRefPubMedPubMedCentral
16.
go back to reference Ghanem N, Pache G, Bley T, Kotter E, Langer M. MR findings in a rare case of sclerosing mesenteritis of the mesocolon. J Magn Reson Imaging. 2005;21:632–6.CrossRefPubMed Ghanem N, Pache G, Bley T, Kotter E, Langer M. MR findings in a rare case of sclerosing mesenteritis of the mesocolon. J Magn Reson Imaging. 2005;21:632–6.CrossRefPubMed
17.
go back to reference Zissin R, Metser U, Hain D, Even-Sapir E. Mesenteric panniculitis in oncologic patients: PET-CT findings. Br J Radiol. 2006;79:37–43.CrossRefPubMed Zissin R, Metser U, Hain D, Even-Sapir E. Mesenteric panniculitis in oncologic patients: PET-CT findings. Br J Radiol. 2006;79:37–43.CrossRefPubMed
18.
go back to reference Ehrenpreis ED, Roginsky G, Gore RM. Clinical significance of mesenteric panniculitis-like abnormalities on abdominal computerized tomography in patients with malignant neoplasms. World J Gastroenterol. 2016;22:10601–8.CrossRefPubMedPubMedCentral Ehrenpreis ED, Roginsky G, Gore RM. Clinical significance of mesenteric panniculitis-like abnormalities on abdominal computerized tomography in patients with malignant neoplasms. World J Gastroenterol. 2016;22:10601–8.CrossRefPubMedPubMedCentral
Metadata
Title
Sclerosing mesenteritis mimicking metachronous peritoneal metastases from descending colon adenocarcinoma
Authors
Toshifumi Watanabe
Shiro Terai
Tomoya Tsukada
Masaki Takeshita
Koshi Matsui
Koji Amaya
Masahide Kaji
Kiichi Maeda
Koichi Shimizu
Junko Saito
Kentaro Mochizuki
Akio Uchiyama
Publication date
01-12-2017
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2017
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-017-1214-4

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