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Published in: BMC Psychiatry 1/2020

Open Access 01-12-2020 | Schizophrenia | Research article

A meta-review of literature reviews assessing the capacity of patients with severe mental disorders to make decisions about their healthcare

Authors: A. Calcedo-Barba, A. Fructuoso, J. Martinez-Raga, S. Paz, M. Sánchez de Carmona, E. Vicens

Published in: BMC Psychiatry | Issue 1/2020

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Abstract

Background

Determining the mental capacity of psychiatric patients for making healthcare related decisions is crucial in clinical practice. This meta-review of review articles comprehensively examines the current evidence on the capacity of patients with a mental illness to make medical care decisions.

Methods

Systematic review of review articles following PRISMA recommendations. PubMed, Scopus, CINAHL and PsycInfo were electronically searched up to 31 January 2020. Free text searches and medical subject headings were combined to identify literature reviews and meta-analyses published in English, and summarising studies on the capacity of patients with serious mental illnesses to make healthcare and treatment related decisions, conducted in any clinical setting and with a quantitative synthesis of results. Publications were selected as per inclusion and exclusion criteria. The AMSTAR II tool was used to assess the quality of reviews.

Results

Eleven publications were reviewed. Variability on methods across studies makes it difficult to precisely estimate the prevalence of decision-making capacity in patients with mental disorders. Nonetheless, up to three-quarters of psychiatric patients, including individuals with serious illnesses such as schizophrenia or bipolar disorder may have capacity to make medical decisions in the context of their illness. Most evidence comes from studies conducted in the hospital setting; much less information exists on the healthcare decision making capacity of mental disorder patients while in the community. Stable psychiatric and non-psychiatric patients may have a similar capacity to make healthcare related decisions. Patients with a mental illness have capacity to judge risk-reward situations and to adequately decide about the important treatment outcomes. Different symptoms may impair different domains of the decisional capacity of psychotic patients. Decisional capacity impairments in psychotic patients are temporal, identifiable, and responsive to interventions directed towards simplifying information, encouraging training and shared decision making. The publications complied satisfactorily with the AMSTAR II critical domains.

Conclusions

Whilst impairments in decision-making capacity may exist, most patients with a severe mental disorder, such as schizophrenia or bipolar disorder are able to make rational decisions about their healthcare. Best practice strategies should incorporate interventions to help mentally ill patients grow into the voluntary and safe use of medications.
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Literature
1.
go back to reference Appelbaum P, Grisso T. The MacArthur treatment competence study. I: mental illness and competence to consent to treatment. Law Hum Behav. 1995;19(2):105–26.PubMed Appelbaum P, Grisso T. The MacArthur treatment competence study. I: mental illness and competence to consent to treatment. Law Hum Behav. 1995;19(2):105–26.PubMed
2.
go back to reference Owen GS, Freyenhagen F, Richardson G, Hotopf M. Mental capacity and decisional autonomy: an interdisciplinary challenge. Inquiry. 2009;52(1):79–107. Owen GS, Freyenhagen F, Richardson G, Hotopf M. Mental capacity and decisional autonomy: an interdisciplinary challenge. Inquiry. 2009;52(1):79–107.
3.
go back to reference Jeste D, Eglit G, PPalmer B, Martinis J, Blanck P, Saks E. Supported decision making in serious mental illness. Psychiatry. 2018;81(1):28–40.PubMed Jeste D, Eglit G, PPalmer B, Martinis J, Blanck P, Saks E. Supported decision making in serious mental illness. Psychiatry. 2018;81(1):28–40.PubMed
5.
go back to reference Harding R, Taşcıoğlu E. Supported decision-making from theory to practice: implementing the right to enjoy legal capacity. Societies. 2018;8(2):25. Harding R, Taşcıoğlu E. Supported decision-making from theory to practice: implementing the right to enjoy legal capacity. Societies. 2018;8(2):25.
6.
go back to reference Morrissey F. The united nations convention on the rights of persons with disabilities: a new approach to decision-making in mental health law. Eur J Health Law. 2012;19(5):423–40.PubMed Morrissey F. The united nations convention on the rights of persons with disabilities: a new approach to decision-making in mental health law. Eur J Health Law. 2012;19(5):423–40.PubMed
7.
go back to reference Mahomed F, Stein MA, Patel V. Involuntary mental health treatment in the era of the United Nations convention on the rights of persons with disabilities. PLoS Med. 2018;15(10):e1002679.PubMedPubMedCentral Mahomed F, Stein MA, Patel V. Involuntary mental health treatment in the era of the United Nations convention on the rights of persons with disabilities. PLoS Med. 2018;15(10):e1002679.PubMedPubMedCentral
8.
go back to reference Danzer G, Rieger SM. Improving medication adherence for severely mentally ill adults by decreasing coercion and increasing cooperation. Bull Menn Clin. 2016;80(1):30–48. Danzer G, Rieger SM. Improving medication adherence for severely mentally ill adults by decreasing coercion and increasing cooperation. Bull Menn Clin. 2016;80(1):30–48.
11.
go back to reference Eiring Ø, Landmark BF, Aas E, Salkeld G, Nylenna M, Nytrøen K. What matters to patients? A systematic review of preferences for medication-associated outcomes in mental disorders. BMJ Open. 2015;5(4):1–13. Eiring Ø, Landmark BF, Aas E, Salkeld G, Nylenna M, Nytrøen K. What matters to patients? A systematic review of preferences for medication-associated outcomes in mental disorders. BMJ Open. 2015;5(4):1–13.
12.
go back to reference Hostiuc S, Rusu MC, Negoi I, Drima E. Testing decision-making competency of schizophrenia participants in clinical trials. A meta-analysis and meta-regression. BMC Psychiatry. 2018;18(1):2.PubMed Hostiuc S, Rusu MC, Negoi I, Drima E. Testing decision-making competency of schizophrenia participants in clinical trials. A meta-analysis and meta-regression. BMC Psychiatry. 2018;18(1):2.PubMed
13.
go back to reference Jeste DV, Depp CA, Palmer BW. Magnitude of impairment in decisional capacity in people with schizophrenia compared to normal subjects: an overview. Schizophr Bull. 2006;32(1):121–8.PubMed Jeste DV, Depp CA, Palmer BW. Magnitude of impairment in decisional capacity in people with schizophrenia compared to normal subjects: an overview. Schizophr Bull. 2006;32(1):121–8.PubMed
14.
go back to reference Larkin A, Hutton P. Systematic review and meta-analysis of factors that help or hinder treatment decision-making capacity in psychosis. Br J Psychiatry. 2017;211(4):205–15.PubMed Larkin A, Hutton P. Systematic review and meta-analysis of factors that help or hinder treatment decision-making capacity in psychosis. Br J Psychiatry. 2017;211(4):205–15.PubMed
15.
go back to reference Lepping P, Stanly T, Turner J. Systematic review on the prevalence of lack of capacity in medical and psychiatric settings. Clin Med J R Coll Physicians London. 2015;15(4):337–43. Lepping P, Stanly T, Turner J. Systematic review on the prevalence of lack of capacity in medical and psychiatric settings. Clin Med J R Coll Physicians London. 2015;15(4):337–43.
16.
go back to reference Mukherjee D, Kable JW. Value-based decision making in mental illness: a meta-analysis. Clin Psychol Sci. 2014;2(6):767–82. Mukherjee D, Kable JW. Value-based decision making in mental illness: a meta-analysis. Clin Psychol Sci. 2014;2(6):767–82.
17.
go back to reference Okai D, Owen G, McGuire H, Singh S, Churchil R, Hotopf M. Mental capacity in psychiatric patients systematic review. Br J Psychiatry. 2007;191:291–7.PubMed Okai D, Owen G, McGuire H, Singh S, Churchil R, Hotopf M. Mental capacity in psychiatric patients systematic review. Br J Psychiatry. 2007;191:291–7.PubMed
18.
go back to reference Ruissen AM, Widdershoven GAM, Meynen G, Abma TA, van Balkom AJLM. A systematic review of the literature about competence and poor insight. Acta Psychiatr Scand. 2012;125(2):103–13.PubMed Ruissen AM, Widdershoven GAM, Meynen G, Abma TA, van Balkom AJLM. A systematic review of the literature about competence and poor insight. Acta Psychiatr Scand. 2012;125(2):103–13.PubMed
19.
go back to reference Spencer BWJ, Shields G, Gergel T, Hotopf M, Owen GS. Diversity or disarray? A systematic review of decision-making capacity for treatment and research in schizophrenia and other non-affective psychoses. Psychol Med. 2017;47(11):1906–22.PubMed Spencer BWJ, Shields G, Gergel T, Hotopf M, Owen GS. Diversity or disarray? A systematic review of decision-making capacity for treatment and research in schizophrenia and other non-affective psychoses. Psychol Med. 2017;47(11):1906–22.PubMed
21.
go back to reference Woodrow A, Sparks S, Bobrovskaia V, Paterson C, Murphy P, Hutton P. Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks. Psychol Med. 2019;49(1):32–38. Woodrow A, Sparks S, Bobrovskaia V, Paterson C, Murphy P, Hutton P. Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks. Psychol Med. 2019;49(1):32–38.
22.
go back to reference Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, et al. AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ. 2017;358:1–9. Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, et al. AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ. 2017;358:1–9.
23.
go back to reference Heerey E, Bell-Warren K, Gold J. Decision-making impairments in the context of intact reward sensitivity in schizophrenia. Biol Psychiatry. 2008;64(1):62–9.PubMedPubMedCentral Heerey E, Bell-Warren K, Gold J. Decision-making impairments in the context of intact reward sensitivity in schizophrenia. Biol Psychiatry. 2008;64(1):62–9.PubMedPubMedCentral
24.
go back to reference Nestor P, Choate V, Niznikiewicz M, Levitt J, Shenton M, McCarley R. Neuropsychology of reward learning and negative symptoms in schizophrenia. Schizophr Res. 2014;159(0):506–8.PubMedPubMedCentral Nestor P, Choate V, Niznikiewicz M, Levitt J, Shenton M, McCarley R. Neuropsychology of reward learning and negative symptoms in schizophrenia. Schizophr Res. 2014;159(0):506–8.PubMedPubMedCentral
26.
go back to reference Gold JM, Waltz JA, Prentice KJ, Morris SE, Heerey EA. Reward processing in schizophrenia: a deficit in the representation of value. Schizophr Bull. 2008;34(5):835–47.PubMedPubMedCentral Gold JM, Waltz JA, Prentice KJ, Morris SE, Heerey EA. Reward processing in schizophrenia: a deficit in the representation of value. Schizophr Bull. 2008;34(5):835–47.PubMedPubMedCentral
27.
go back to reference Maguire S, Rea SM. Convery. Electroconvulsive therapy - what do patients think of their treatment? Ulster Med J. 2016;85(3):182–6.PubMedPubMedCentral Maguire S, Rea SM. Convery. Electroconvulsive therapy - what do patients think of their treatment? Ulster Med J. 2016;85(3):182–6.PubMedPubMedCentral
28.
go back to reference Nakanishi M, Setoya Y, Kodaka M, Makino H, Nishimura A, Yamauchi K, et al. Symptom dimensions and needs of care among patients with schizophrenia in hospital and the community. Psychiatry Clin Neurosci. 2007;61(5):495–501.PubMed Nakanishi M, Setoya Y, Kodaka M, Makino H, Nishimura A, Yamauchi K, et al. Symptom dimensions and needs of care among patients with schizophrenia in hospital and the community. Psychiatry Clin Neurosci. 2007;61(5):495–501.PubMed
29.
go back to reference Maitre E, Debien C, Nicaise P, Wyngaerden F, LeGadulec M, et al. Advanced directives in psychiatry: a review of the qualitative literature, a state-of-the-art and viewpoints. Encephale. 2013;39(4):244–51.PubMed Maitre E, Debien C, Nicaise P, Wyngaerden F, LeGadulec M, et al. Advanced directives in psychiatry: a review of the qualitative literature, a state-of-the-art and viewpoints. Encephale. 2013;39(4):244–51.PubMed
30.
go back to reference Wilder C, Elbogen E, Moser L, Swanson J, Swartz M. Medication preferences and adherence among individuals with severe mental illness who completed psychiatric advance directives. Psychiatr Serv. 2010;61(4):380–5.PubMed Wilder C, Elbogen E, Moser L, Swanson J, Swartz M. Medication preferences and adherence among individuals with severe mental illness who completed psychiatric advance directives. Psychiatr Serv. 2010;61(4):380–5.PubMed
33.
go back to reference Stovell D, Morrison AP, Panayiotou M, Hutton P. Shared treatment decision-making and empowerment-related outcomes in psychosis: systematic review and meta-analysis. Br J Psychiatry. 2016;209(1):23–8.PubMed Stovell D, Morrison AP, Panayiotou M, Hutton P. Shared treatment decision-making and empowerment-related outcomes in psychosis: systematic review and meta-analysis. Br J Psychiatry. 2016;209(1):23–8.PubMed
34.
go back to reference Dornan J, Kennedy M, Garland J, Rutledge E, Kennedy HG. Functional mental capacity, treatment as usual and time: magnitude of change in secure hospital patients with major mental illness psychiatry. BMC Res Notes. 2015;8(1):1–9. Dornan J, Kennedy M, Garland J, Rutledge E, Kennedy HG. Functional mental capacity, treatment as usual and time: magnitude of change in secure hospital patients with major mental illness psychiatry. BMC Res Notes. 2015;8(1):1–9.
36.
go back to reference Schaefer LA. MacArthur competence assessment tools. In: Kreutzer J.S., DeLuca J., Caplan B. (eds) Encyclopedia of Clinical Neuropsychology. New York: Springer; 2011. Schaefer LA. MacArthur competence assessment tools. In: Kreutzer J.S., DeLuca J., Caplan B. (eds) Encyclopedia of Clinical Neuropsychology. New York: Springer; 2011.
37.
go back to reference Owen G, David A, Hayward P, et al. Retrospective views of psychiatric in-patients regaining mental capacity. Br J Psychiatry. 2009;195(5):403–7.PubMed Owen G, David A, Hayward P, et al. Retrospective views of psychiatric in-patients regaining mental capacity. Br J Psychiatry. 2009;195(5):403–7.PubMed
38.
go back to reference Moser DJ, Reese RL, Hey CT, Schultz SK, Arndt S, Beglinger LJ, et al. Using a brief intervention to improve decisional capacity in schizophrenia research. Schizophr Bull. 2006;32(1):116–20.PubMed Moser DJ, Reese RL, Hey CT, Schultz SK, Arndt S, Beglinger LJ, et al. Using a brief intervention to improve decisional capacity in schizophrenia research. Schizophr Bull. 2006;32(1):116–20.PubMed
39.
go back to reference Wang X, Yu X, Appelbaum S, Tang H, Yao G, Si T, et al. Longitudinal informed consent competency in stable community patients with schizophrenia: a one-week training and one-year follow-up study. Schizophr Res. 2016;170(1):162–7.PubMed Wang X, Yu X, Appelbaum S, Tang H, Yao G, Si T, et al. Longitudinal informed consent competency in stable community patients with schizophrenia: a one-week training and one-year follow-up study. Schizophr Res. 2016;170(1):162–7.PubMed
41.
go back to reference Jacob K. Recovery model of mental illness: a complementary approach to psychiatric care. Indian J Psychol Med. 2015;37(2):117–9.PubMedPubMedCentral Jacob K. Recovery model of mental illness: a complementary approach to psychiatric care. Indian J Psychol Med. 2015;37(2):117–9.PubMedPubMedCentral
Metadata
Title
A meta-review of literature reviews assessing the capacity of patients with severe mental disorders to make decisions about their healthcare
Authors
A. Calcedo-Barba
A. Fructuoso
J. Martinez-Raga
S. Paz
M. Sánchez de Carmona
E. Vicens
Publication date
01-12-2020
Publisher
BioMed Central
Keyword
Schizophrenia
Published in
BMC Psychiatry / Issue 1/2020
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-020-02756-0

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