Scalp Metastases as a Rare Primary First Manifestation of Gallbladder Cancer

Gallbladder cancer (GBC) with cutaneous metastases is a rare entity. Metastases on the scalp is even rarer and an unusual metastatic pattern of GBC. Only 12 cases have been reported so far. We herein report a case of a 52-year-old woman who presented with subcutaneous nodule over the scalp with pain in the right upper abdomen. Fine-needle aspiration cytology (FNAC) of this nodule revealed metastatic adenocarcinoma. Contrast-enhanced computed tomography scan of the abdomen showed an advanced GBC confirmed by FNAC from the gallbladder mass. She was put on palliative combination chemotherapy but rapidly developed multiple scalp nodules and jaundice with dramatic deterioration. This report highlights the possible scalp metastasis from advanced GBC that portends an ominous prognosis.