Skip to main content
Top
Published in: Virology Journal 1/2021

Open Access 01-12-2021 | SARS-CoV-2 | Case Report

Impact of joint management of a COVID-19 mother and her newborn on the virus transmission: a case report

Authors: Maria Chiara De Nardo, Anna Rita Bellomo, Francesca Perfetti, Francesco Antonino Battaglia, Miriam Lichtner, Riccardo Lubrano

Published in: Virology Journal | Issue 1/2021

Login to get access

Abstract

Background

Since last year, COVID-19, the disease caused by the novel Sars-Cov-2 virus, has been globally spread to all the world. COVID-19 infection among pregnant women has been described. However, transplacental transmission of Sars-Cov-2 virus from infected mother to the newborn is not yet established. The appropriate management of infants born to mothers with confirmed or suspected COVID-19 and the start of early breastfeeding are being debated.

Case presentation

We report a case of the joint management of a healthy neonate with his mother tested positive for Covid-19 before the delivery and throughout neonatal follow-up. The infection transmission from the mother to her baby is not described, even after a long period of contact between them and breastfeeding.

Conclusion

It may consider an appropriate practice to keep mother and her newborn infant together in order to facilitate their contact and to encourage breastfeeding, although integration with infection prevention measures is needed.
Literature
1.
go back to reference Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;6:66. Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;6:66.
2.
go back to reference Walker KF, O’Donoghue K, Grace N, et al. Maternal transmission of SARS-COV-2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis. BJOG. 2020;127:1324.CrossRef Walker KF, O’Donoghue K, Grace N, et al. Maternal transmission of SARS-COV-2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis. BJOG. 2020;127:1324.CrossRef
4.
go back to reference Cojocaru L, Crimmins S, Sundararajan S, et al. An initiative to evaluate the safety of maternal bonding in patients with SARS-CoV-2 infection. J Matern Fetal Neonatal Med. 2020;6:1. Cojocaru L, Crimmins S, Sundararajan S, et al. An initiative to evaluate the safety of maternal bonding in patients with SARS-CoV-2 infection. J Matern Fetal Neonatal Med. 2020;6:1.
5.
go back to reference Gale C, Quigley MA, Placzek A, et al. Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance. Lancet Child Adolesc Health. 2021;5:113.CrossRef Gale C, Quigley MA, Placzek A, et al. Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance. Lancet Child Adolesc Health. 2021;5:113.CrossRef
6.
go back to reference Ronchi A, Pietrasanta C, Zavattoni M, et al. Evaluation of rooming-in practice for neonates born to mothers with severe acute respiratory syndrome coronavirus 2 infection in Italy. JAMA Pediatr. 2021;175:260.CrossRef Ronchi A, Pietrasanta C, Zavattoni M, et al. Evaluation of rooming-in practice for neonates born to mothers with severe acute respiratory syndrome coronavirus 2 infection in Italy. JAMA Pediatr. 2021;175:260.CrossRef
7.
go back to reference Elshafeey F, Magdi R, Hindi N, et al. A systematic scoping review of COVID-19 during pregnancy and childbirth. Int J Gynaecol Obstet. 2020;150:47.CrossRef Elshafeey F, Magdi R, Hindi N, et al. A systematic scoping review of COVID-19 during pregnancy and childbirth. Int J Gynaecol Obstet. 2020;150:47.CrossRef
8.
go back to reference Liu W, Wang J, Li W, et al. Clinical characteristics of 19 neonates born to mothers with COVID-19. Front Med. 2020;14:193.CrossRef Liu W, Wang J, Li W, et al. Clinical characteristics of 19 neonates born to mothers with COVID-19. Front Med. 2020;14:193.CrossRef
9.
go back to reference Kirtsman M, Diambomba Y, Poutanen SM, et al. Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection. CMAJ. 2020;192:E647.CrossRef Kirtsman M, Diambomba Y, Poutanen SM, et al. Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection. CMAJ. 2020;192:E647.CrossRef
10.
go back to reference Wu Y, Liu C, Dong L, et al. Coronavirus disease 2019 among pregnant Chinese women: case series data on the safety of vaginal birth and breastfeeding. BJOG. 2020;127:1109.CrossRef Wu Y, Liu C, Dong L, et al. Coronavirus disease 2019 among pregnant Chinese women: case series data on the safety of vaginal birth and breastfeeding. BJOG. 2020;127:1109.CrossRef
11.
go back to reference Groß R, Conzelmann C, Müller JA, et al. Detection of SARS-CoV-2 in human breastmilk. Lancet. 2020;395:1757.CrossRef Groß R, Conzelmann C, Müller JA, et al. Detection of SARS-CoV-2 in human breastmilk. Lancet. 2020;395:1757.CrossRef
12.
go back to reference Chambers C, Krogstad P, Bertrand K, et al. Evaluation for SARS-CoV-2 in breast milk from 18 infected women. JAMA. 2020;324:1347.CrossRef Chambers C, Krogstad P, Bertrand K, et al. Evaluation for SARS-CoV-2 in breast milk from 18 infected women. JAMA. 2020;324:1347.CrossRef
13.
go back to reference Wang L, Shi Y, Xiao T, Fu J, Feng X, Mu D, et al. Chinese expert consensus on the perinatal and neonatal management for the prevention and control of the 2019 novel coronavirus infection (first edition). Ann Transl Med. 2020;6:66. Wang L, Shi Y, Xiao T, Fu J, Feng X, Mu D, et al. Chinese expert consensus on the perinatal and neonatal management for the prevention and control of the 2019 novel coronavirus infection (first edition). Ann Transl Med. 2020;6:66.
14.
go back to reference Puopolo K, Kimberlin D. Management of infants born to mothers with COVID-19 date of document: April 2, 2020. Am AcadPediatr Comm Fetus Newborn Sect Neonatal Perinat MedComm Infect Dis. 2020;6:66. Puopolo K, Kimberlin D. Management of infants born to mothers with COVID-19 date of document: April 2, 2020. Am AcadPediatr Comm Fetus Newborn Sect Neonatal Perinat MedComm Infect Dis. 2020;6:66.
15.
go back to reference Management of infants born to mothers with suspected or confirmed COVID-19 date of document: November 2, 2020. Am Acad Pediatr Comm Fetus Newborn, Sect Neonatal Perinat Med Comm Infect Dis. 2020. Management of infants born to mothers with suspected or confirmed COVID-19 date of document: November 2, 2020. Am Acad Pediatr Comm Fetus Newborn, Sect Neonatal Perinat Med Comm Infect Dis. 2020.
16.
go back to reference Davanzo R, Moro G, Sandri F, Agosti M, Moretti C, Mosca F. Breastfeeding and coronavirus disease-2019. Ad interim indications of the Italian Society of Neonatology endorsed by the Union Of European Neonatal & Perinatal Societies. Matern Child Nutr. 2020;6:66. Davanzo R, Moro G, Sandri F, Agosti M, Moretti C, Mosca F. Breastfeeding and coronavirus disease-2019. Ad interim indications of the Italian Society of Neonatology endorsed by the Union Of European Neonatal & Perinatal Societies. Matern Child Nutr. 2020;6:66.
17.
go back to reference WHO. Clinical Management Of Severe Acute Respiratory Infection (SARI) When COVID-19 Disease Is Suspected: Interim Guidance V 1.2. WHO; 2020. WHO. Clinical Management Of Severe Acute Respiratory Infection (SARI) When COVID-19 Disease Is Suspected: Interim Guidance V 1.2. WHO; 2020.
19.
go back to reference Royal College Of Obstetricians And Gynaecologists. Coronavirus (COVID-19) Infection In Pregnancy Information For Healthcare Professionals. Centers For Disease Control And Prevention. 2020 Royal College Of Obstetricians And Gynaecologists. Coronavirus (COVID-19) Infection In Pregnancy Information For Healthcare Professionals. Centers For Disease Control And Prevention. 2020
21.
go back to reference Salvatore CM, Han JY, Acker KP, et al. Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study. Lancet Child Adolesc Health. 2020;4:721.CrossRef Salvatore CM, Han JY, Acker KP, et al. Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study. Lancet Child Adolesc Health. 2020;4:721.CrossRef
22.
go back to reference La Scola B, Le Bideau M, Andreani J, et al. Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards. Eur J Clin Microbiol Infect Dis. 2020;39(6):1059–61.CrossRef La Scola B, Le Bideau M, Andreani J, et al. Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards. Eur J Clin Microbiol Infect Dis. 2020;39(6):1059–61.CrossRef
23.
go back to reference Zheng S, Fan J, Yu F, et al. Viral load dynamics and disease severity in patients infected with SARS-CoV-2 in Zhejiang province, China, January-March 2020: retrospective cohort study. BMJ. 2020;369:e1443.CrossRef Zheng S, Fan J, Yu F, et al. Viral load dynamics and disease severity in patients infected with SARS-CoV-2 in Zhejiang province, China, January-March 2020: retrospective cohort study. BMJ. 2020;369:e1443.CrossRef
24.
go back to reference Liu Y, Yan LM, Wan L, et al. Viral dynamics in mild and severe cases of COVID-19. Lancet Infect Dis. 2020;20(6):656–7.CrossRef Liu Y, Yan LM, Wan L, et al. Viral dynamics in mild and severe cases of COVID-19. Lancet Infect Dis. 2020;20(6):656–7.CrossRef
25.
go back to reference He X, Lau EHY, Wu P, et al. Temporal dynamics in viral shedding and transmissibility of COVID-19. Nat Med. 2020;26(5):672–5.CrossRef He X, Lau EHY, Wu P, et al. Temporal dynamics in viral shedding and transmissibility of COVID-19. Nat Med. 2020;26(5):672–5.CrossRef
26.
go back to reference To KK, Tsang OT, Leung WS, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020;20(5):565–74.CrossRef To KK, Tsang OT, Leung WS, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020;20(5):565–74.CrossRef
Metadata
Title
Impact of joint management of a COVID-19 mother and her newborn on the virus transmission: a case report
Authors
Maria Chiara De Nardo
Anna Rita Bellomo
Francesca Perfetti
Francesco Antonino Battaglia
Miriam Lichtner
Riccardo Lubrano
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Virology Journal / Issue 1/2021
Electronic ISSN: 1743-422X
DOI
https://doi.org/10.1186/s12985-021-01598-w

Other articles of this Issue 1/2021

Virology Journal 1/2021 Go to the issue
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.