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BMC Geriatrics

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Open Access 01-12-2023 | Sarcopenia | Research

The association between sedentary behaviour and sarcopenia in older adults: a systematic review and meta-analysis

Authors: Yihan Mo, Yuxin Zhou, Helen Chan, Catherine Evans, Matthew Maddocks

Published in: BMC Geriatrics | Issue 1/2023

Abstract

Background

Sedentary behaviour is considered to contribute to sarcopenia when combined with physical inactivity. Whether sedentary behaviour is independently associated with sarcopenia remains controversial. The aim of this study is to explore the association between sedentary behaviour and sarcopenia in older adults in community and long-term care facility settings.

Methods

Eight electronic databases including MEDLINE, PsycINFO, Wanfang were searched from inception until August 2023. The review included cross-sectional and longitudinal studies concerning the association between sedentary behaviour and sarcopenia among participants over 60 years old. Evidence was pooled by both random-effects meta-analysis and narrative synthesis. Subgroup analyses explored variation according to adjustment of physical activity, settings, and measurements of sedentary behaviour and sarcopenia. Quality assessment for individual studies was performed with the Joanna Briggs Institute (JBI) Critical Appraisal Checklist.

Results

Seventeen articles (16 cross-sectional studies and 1 longitudinal study) of 25,788 participants from community or long-term care facility settings were included. The overall quality of the included studies was rated high. Meta-analysis of 14 cross-sectional studies showed that sedentary behaviour was independently positively associated with sarcopenia: pooled odd ratio 1.36 (95% confidence interval, 1.18–1.58). The independent positive association remained in subgroup analyses by adjustment of physical activity, settings, and measurements of sedentary behaviour and sarcopenia. The narrative analysis corroborated the findings of the meta-analysis and provided additional evidence suggesting that interruptions in sedentary periods were linked to a decreased likelihood of developing sarcopenia.

Conclusions

The findings support the hypothesis that sedentary behaviour is independently positively associated with sarcopenia in older adults, providing vital indications for the development of strategies to prevent sarcopenia.

Systematic review registration

The systematic review protocol has been registered with the PROSPERO database (CRD42022311399).

Available only for authorised users

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Title: The association between sedentary behaviour and sarcopenia in older adults: a systematic review and meta-analysis
Authors: Yihan Mo
Yuxin Zhou
Helen Chan
Catherine Evans
Matthew Maddocks
Publication date: 01-12-2023
Publisher: BioMed Central
Keyword: Sarcopenia
Published in: BMC Geriatrics / Issue 1/2023
Electronic ISSN: 1471-2318
DOI: https://doi.org/10.1186/s12877-023-04489-7

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