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BMC Nephrology
Published in: BMC Nephrology 1/2024

Open Access 01-12-2024 | Sarcopenia | Research

The role of ultra-processed food consumption in protein-energy wasting and sarcopenia development in patients with chronic kidney diseases

Authors: Zainab Shateri, Sevda Eskandarzadeh, Mehran Nouri, Shahrokh Ezzatzadegan Jahromi, Fatemeh Mansouri, Siavash Babajafari

Published in: BMC Nephrology | Issue 1/2024

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Abstract

Background

The effect of ultra-processed foods (UPFs) on chronic kidney disease (CKD) has been studied in some studies. The present study aimed to investigate the association between UPF consumption and the risk of protein-energy wasting (PEW) and sarcopenia in patients with CKD in the Iranian population.

Methods

The current cross-sectional study included 110 patients with CKD referred to two clinics in Shiraz, Iran. The International Society of Renal Nutrition and Metabolism (ISRNM) criteria and the Asian Working Group for Sarcopenia (AWGS) guideline were considered for the diagnosis of PEW and sarcopenia, respectively. The valid semi-quantitative food frequency questionnaire was used to assess participants' dietary intake. The logistic regression was used to examine the association of UPFs with PEW and sarcopenia.

Results

We observed no significant association between sarcopenia and PEW with UPFs in the crude model. After adjusting for confounders, we observed a significantly higher odds of sarcopenia in the upper versus lower median of UPF intake (odds ratio (OR) = 3.59, 95% confidence interval (CI): 1.02–12.62, P = 0.046).

Conclusions

Our findings suggest a positive relationship between UPF intake and sarcopenia among CKD patients. Therefore, reducing the intake of UPFs may decrease the odds of sarcopenia in patients suffering from CKD.
Appendix
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Metadata
Title
The role of ultra-processed food consumption in protein-energy wasting and sarcopenia development in patients with chronic kidney diseases
Authors
Zainab Shateri
Sevda Eskandarzadeh
Mehran Nouri
Shahrokh Ezzatzadegan Jahromi
Fatemeh Mansouri
Siavash Babajafari
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Nephrology / Issue 1/2024
Electronic ISSN: 1471-2369
DOI
https://doi.org/10.1186/s12882-023-03409-6

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Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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