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13-05-2024 | Appendicitis | SAGES/EAES Official Publication

SAGES guideline for the diagnosis and treatment of appendicitis

Authors: Sunjay S. Kumar, Amelia T. Collings, Ryan Lamm, Ivy N. Haskins, Stefan Scholz, Pramod Nepal, Arianne T. Train, Dimitrios I. Athanasiadis, Philip H. Pucher, Joel F. Bradley III, Nader M. Hanna, Francisco Quinteros, Nisha Narula, Bethany J. Slater

Published in: Surgical Endoscopy | Issue 6/2024

Abstract

Background

Appendicitis is an extremely common disease with a variety of medical and surgical treatment approaches. A multidisciplinary expert panel was convened to develop evidence-based recommendations to support clinicians and patients in decisions regarding the diagnosis and treatment of appendicitis.

Methods

A systematic review was conducted from 2010 to 2022 to answer 8 key questions relating to the diagnosis of appendicitis, operative or nonoperative management, and specific technical and post-operative issues for appendectomy. The results of this systematic review were then presented to a panel of adult and pediatric surgeons. Evidence-based recommendations were formulated using the GRADE methodology by subject experts.

Results

Conditional recommendations were made in favor of uncomplicated and complicated appendicitis being managed operatively, either delayed (>12h) or immediate operation (<12h), either suction and lavage or suction alone, no routine drain placement, treatment with short-term antibiotics postoperatively for complicated appendicitis, and complicated appendicitis previously treated nonoperatively undergoing interval appendectomy. A conditional recommendation signals that the benefits of adhering to a recommendation probably outweigh the harms although it does also indicate uncertainty.

Conclusions

These recommendations should provide guidance with regard to current controversies in appendicitis. The panel also highlighted future research opportunities where the evidence base can be strengthened.

Available only for authorised users

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Title: SAGES guideline for the diagnosis and treatment of appendicitis
Authors: Sunjay S. Kumar
Amelia T. Collings
Ryan Lamm
Ivy N. Haskins
Stefan Scholz
Pramod Nepal
Arianne T. Train
Dimitrios I. Athanasiadis
Philip H. Pucher
Joel F. Bradley III
Nader M. Hanna
Francisco Quinteros
Nisha Narula
Bethany J. Slater
Publication date: 13-05-2024
Publisher: Springer US
Keywords: Appendicitis
Appendicitis
Appendectomy
Antibiotic
Pediatrics
Published in: Surgical Endoscopy / Issue 6/2024
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-024-10813-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

SAGES guideline for the diagnosis and treatment of appendicitis

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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