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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 2/2015

01-02-2015 | Breast Oncology

Safely Expanding the Use of Nipple-Sparing Mastectomy in BRCA Mutation Carriers

Author: Amy E. Cyr, MD, FACS

Published in: Annals of Surgical Oncology | Issue 2/2015

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Excerpt

This past year, I presented data supporting the safety of nipple-sparing mastectomy (NSM) to a Latin American audience. After the talk, one of the participants thanked me for the talk but she was disheartened that the local medical oncologist described my presentation to his colleagues as nothing less than blasphemy. Although recently more accepting of NSM, our medical community also questions the oncologic safety of NSM. Should it be limited to prophylactic procedures? Is it safe for women with more advanced disease or with BRCA mutations? …
Literature
1.
Yao K, Liederbach E, Tang R, et al. Nipple sparing mastectomy in BRCA1/2 mutation carriers: an interim analysis and review of the literature. Ann Surg Oncol. 2014. doi:10.​1245/​s10434-014-3883-3.
2.
Hartman LC, Schaid DJ, Woods JE, et al. Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer. N Engl J Med. 1999;340:77-84.CrossRef
3.
Gerber B, Krause A, Dieterich M, Kundt G, Reimer T. The oncologic safety of skin sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction: an extended follow-up study. Ann Surg Oncol. 2009;249:461-8.CrossRef
4.
5.
Coopey WB, Tang R, Lei L, et al. Increasing eligibility for nipple-sparing mastectomy. Ann Surg Oncol. 2013;20:3218-22.PubMedCrossRef
Metadata
Title
Safely Expanding the Use of Nipple-Sparing Mastectomy in BRCA Mutation Carriers
Author
Amy E. Cyr, MD, FACS
Publication date
01-02-2015
Publisher
Springer US
Published in
Annals of Surgical Oncology / Issue 2/2015
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-014-4007-9

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