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Critical Care
Published in: Critical Care 3/2012

Open Access 01-06-2012 | Letter

ROTEM®-guided coagulation factor concentrate therapy in trauma: 2-year experience in Venice, Italy

Authors: Alberto Grassetto, Marco De Nardin, Bernadetta Ganzerla, Monica Geremia, Debora Saggioro, Elena Serafini, Silvia Zampieri, Manuela Toffoli, Daniele Penzo, Antonio Bossi, Carlo Maggiolo

Published in: Critical Care | Issue 3/2012

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Excerpt

Haemostatic therapy for trauma-induced coagulopathy is typically based on administration of allogeneic blood products, although the evidence supporting this approach is poor [1]. Fixed-ratio protocols have been proposed for administering fresh frozen plasma, red blood cells and platelets, but the optimal ratio has not been established and the speed of intervention may be more important [2]. …
Literature
1.
Yang L, Stanworth S, Hopewell S, Doree C, Murphy M: Is fresh-frozen plasma clinically effective? An update of a systematic review of randomized controlled trials. Transfusion 2012. [Epub ahead of print]
2.
Riskin DJ, Tsai TC, Riskin L, Hernandez-Boussard T, Purtill M, Maggio PM, Spain DA, Brundage SI: Massive transfusion protocols: the role of aggressive resuscitation versus product ratio in mortality reduction. J Am Coll Surg 2009, 209: 198-205. 10.1016/j.jamcollsurg.2009.04.016CrossRefPubMed
3.
Schöchl H, Maegele M, Solomon C, Görlinger K, Voelckel W: Early and individualized goal-directed therapy for trauma-induced coagulopathy. Scand J Trauma Resusc Emerg Med 2012, 20: 15. 10.1186/1757-7241-20-15PubMedCentralCrossRefPubMed
4.
Rossaint R, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernandez-Mondejar E, Hunt BJ, Komadina R, Nardi G, Neugebauer E, Ozier Y, Riddez L, Schultz A, Stahel PF, Vincent JL , Spahn DR: Management of bleeding following major trauma: an updated European guideline. Crit Care 2010, 14: R52. 10.1186/cc8943PubMedCentralCrossRefPubMed
Metadata
Title
ROTEM®-guided coagulation factor concentrate therapy in trauma: 2-year experience in Venice, Italy
Authors
Alberto Grassetto
Marco De Nardin
Bernadetta Ganzerla
Monica Geremia
Debora Saggioro
Elena Serafini
Silvia Zampieri
Manuela Toffoli
Daniele Penzo
Antonio Bossi
Carlo Maggiolo
Publication date
01-06-2012
Publisher
BioMed Central
Published in
Critical Care / Issue 3/2012
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc11322

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