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Published in: Critical Care 2/2010

Open Access 01-04-2010 | Research

Management of bleeding following major trauma: an updated European guideline

Authors: Rolf Rossaint, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Philip F Stahel, Jean-Louis Vincent, Donat R Spahn

Published in: Critical Care | Issue 2/2010

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Abstract

Introduction

Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient, which when implemented may improve patient outcomes.

Methods

The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document presents an updated version of the guideline published by the group in 2007. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature.

Results

Key changes encompassed in this version of the guideline include new recommendations on coagulation support and monitoring and the appropriate use of local haemostatic measures, tourniquets, calcium and desmopressin in the bleeding trauma patient. The remaining recommendations have been reevaluated and graded based on literature published since the last edition of the guideline. Consideration was also given to changes in clinical practice that have taken place during this time period as a result of both new evidence and changes in the general availability of relevant agents and technologies.

Conclusions

This guideline provides an evidence-based multidisciplinary approach to the management of critically injured bleeding trauma patients.
Appendix
Available only for authorised users
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Metadata
Title
Management of bleeding following major trauma: an updated European guideline
Authors
Rolf Rossaint
Bertil Bouillon
Vladimir Cerny
Timothy J Coats
Jacques Duranteau
Enrique Fernández-Mondéjar
Beverley J Hunt
Radko Komadina
Giuseppe Nardi
Edmund Neugebauer
Yves Ozier
Louis Riddez
Arthur Schultz
Philip F Stahel
Jean-Louis Vincent
Donat R Spahn
Publication date
01-04-2010
Publisher
BioMed Central
Published in
Critical Care / Issue 2/2010
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc8943

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