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Published in: Drugs 14/2002

01-10-2002 | Adis New Drug Profile

Rosuvastatin

A Viewpoint by Anders C. Olsson

Author: Anders C. Olsson

Published in: Drugs | Issue 14/2002

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Excerpt

The development of rosuvastatin suggests that this drug may be useful in the treatment and prevention of cardiovascular disease. Rosuvastatin is an appealing statin to the clinician in several ways. It has a marked inhibitory effect on hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase and shows an effective hepatic selectivity, unlike other HMG-CoA reductase inhibitors, which might be of importance with regard to the risk of adverse effects. In addition, it has a low propensity for pharmacokinetic drug interactions and is metabolised very slowly by hepatocytes. …
Metadata
Title
Rosuvastatin
A Viewpoint by Anders C. Olsson
Author
Anders C. Olsson
Publication date
01-10-2002
Publisher
Springer International Publishing
Published in
Drugs / Issue 14/2002
Print ISSN: 0012-6667
Electronic ISSN: 1179-1950
DOI
https://doi.org/10.2165/00003495-200262140-00009

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