Skip to main content
Top
Published in: Current Obesity Reports 4/2017

01-12-2017 | Metabolism (CJ Billington, Section Editor)

Role of Sex and the Environment in Moderating Weight Gain Due to Inadequate Sleep

Authors: Jamie E. Coborn, Monica M. Houser, Claudio E. Perez-Leighton, Jennifer A. Teske

Published in: Current Obesity Reports | Issue 4/2017

Login to get access

Abstract

Purpose of Review

The growing prevalence of obesity, inadequate sleep and sleep disorders together with the negative impact of lack of sleep on overall health highlights the need for therapies targeted towards weight gain due to sleep loss.

Recent Findings

Sex disparities in obesity and sleep disorders are present; yet, the role of sex is inadequately addressed and thus it is unclear whether sensitivity to sleep disruption differs between men and women. Like sex, environmental factors contribute to the development of obesity and poor sleep. The obesogenic environment is characterized by easy access to palatable foods and a low demand for energy expenditure in daily activities. These and other environmental factors are discussed, as they drive altered sleep or their interaction with food choice and intake can promote obesity.

Summary

We discuss data that suggest differences in sleep patterns and responses to sleep disruption influence sex disparities in weight gain, and that enviromental disturbances alter sleep and interact with features of the obesogenic environment that together promote obesity.
Literature
11.
go back to reference Nugent CN, Black LI. Sleep duration, quality of sleep, and use of sleep medication, by sex and family type, 2013-2014. NCHS Data Brief. 2016(230):1–8. Nugent CN, Black LI. Sleep duration, quality of sleep, and use of sleep medication, by sex and family type, 2013-2014. NCHS Data Brief. 2016(230):1–8.
27.
go back to reference Phillips BG, Hisel TM, Kato M, Pesek CA, Dyken ME, Narkiewicz K, et al. Recent weight gain in patients with newly diagnosed obstructive sleep apnea. J Hypertens. 1999;17(9):1297–300.CrossRefPubMed Phillips BG, Hisel TM, Kato M, Pesek CA, Dyken ME, Narkiewicz K, et al. Recent weight gain in patients with newly diagnosed obstructive sleep apnea. J Hypertens. 1999;17(9):1297–300.CrossRefPubMed
29.
go back to reference Yang D, Liu ZH, Zhao Q, Luo Q. Effects of nasal continuous positive airway pressure treatment on insulin resistance and ghrelin levels in non-diabetic apnoeic patients with coronary heart disease. Chin Med J. 2013;126(17):3316–20.PubMed Yang D, Liu ZH, Zhao Q, Luo Q. Effects of nasal continuous positive airway pressure treatment on insulin resistance and ghrelin levels in non-diabetic apnoeic patients with coronary heart disease. Chin Med J. 2013;126(17):3316–20.PubMed
30.
go back to reference Barbe F, Duran-Cantolla J, Sanchez-de-la-Torre M, Martinez-Alonso M, Carmona C, Barcelo A, et al. Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. JAMA. 2012;307(20):2161–8. https://doi.org/10.1001/jama.2012.4366.CrossRefPubMed Barbe F, Duran-Cantolla J, Sanchez-de-la-Torre M, Martinez-Alonso M, Carmona C, Barcelo A, et al. Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. JAMA. 2012;307(20):2161–8. https://​doi.​org/​10.​1001/​jama.​2012.​4366.CrossRefPubMed
31.
go back to reference Salord N, Mayos M, Miralda RM, Farre A, Carreras M, Sust R, et al. Continuous positive airway pressure in clinically stable patients with mild-to-moderate obesity hypoventilation syndrome and obstructive sleep apnoea. Respirology. 2013;18(7):1135–42. https://doi.org/10.1111/resp.12131.PubMed Salord N, Mayos M, Miralda RM, Farre A, Carreras M, Sust R, et al. Continuous positive airway pressure in clinically stable patients with mild-to-moderate obesity hypoventilation syndrome and obstructive sleep apnoea. Respirology. 2013;18(7):1135–42. https://​doi.​org/​10.​1111/​resp.​12131.PubMed
35.
go back to reference Koehl M, Battle S, Meerlo. Sex differences in sleep: the response to sleep deprivation and restraint stress in mice. Sleep. 2006;29(9):1224–31.CrossRefPubMed Koehl M, Battle S, Meerlo. Sex differences in sleep: the response to sleep deprivation and restraint stress in mice. Sleep. 2006;29(9):1224–31.CrossRefPubMed
36.
go back to reference Paul KN, Dugovic C, Turek FW, Laposky AD. Diurnal sex differences in the sleep-wake cycle of mice are dependent on gonadal function. Sleep. 2006;29(9):1211–23.CrossRefPubMed Paul KN, Dugovic C, Turek FW, Laposky AD. Diurnal sex differences in the sleep-wake cycle of mice are dependent on gonadal function. Sleep. 2006;29(9):1211–23.CrossRefPubMed
37.
go back to reference Fang J, Fishbein W. Sex differences in paradoxical sleep: influences of estrus cycle and ovariectomy. Brain Res. 1996;734(1–2):275–85.CrossRefPubMed Fang J, Fishbein W. Sex differences in paradoxical sleep: influences of estrus cycle and ovariectomy. Brain Res. 1996;734(1–2):275–85.CrossRefPubMed
38.
go back to reference • Mong JA, Cusmano DM. Sex differences in sleep: impact of biological sex and sex steroids. Philos Trans R Soc Lond Ser B Biol Sci. 2016;371(1688):20150110. https://doi.org/10.1098/rstb.2015.0110. Review supporting sex disparities in sleep and the influential role of biological sex and sex steroids on sleep. CrossRef • Mong JA, Cusmano DM. Sex differences in sleep: impact of biological sex and sex steroids. Philos Trans R Soc Lond Ser B Biol Sci. 2016;371(1688):20150110. https://​doi.​org/​10.​1098/​rstb.​2015.​0110. Review supporting sex disparities in sleep and the influential role of biological sex and sex steroids on sleep. CrossRef
39.
go back to reference Koehl M, Battle SE, Turek FW. Sleep in female mice: a strain comparison across the estrous cycle. Sleep. 2003;26(3):267–72.CrossRefPubMed Koehl M, Battle SE, Turek FW. Sleep in female mice: a strain comparison across the estrous cycle. Sleep. 2003;26(3):267–72.CrossRefPubMed
40.
go back to reference Schwierin B, Borbely AA, Tobler I. Sleep homeostasis in the female rat during the estrous cycle. Brain Res. 1998;811(1–2):96–104.CrossRefPubMed Schwierin B, Borbely AA, Tobler I. Sleep homeostasis in the female rat during the estrous cycle. Brain Res. 1998;811(1–2):96–104.CrossRefPubMed
42.
go back to reference Rutskova EM, Pigareva ML. Efficiency of the "disk-over-water" method without feedback for sleep deprivation in rats. Zh Vyssh Nerv Deiat Im I P Pavlova. 2009;59(2):245–51.PubMed Rutskova EM, Pigareva ML. Efficiency of the "disk-over-water" method without feedback for sleep deprivation in rats. Zh Vyssh Nerv Deiat Im I P Pavlova. 2009;59(2):245–51.PubMed
43.
go back to reference Kushida CA, Bergmann BM, Rechtschaffen A. Sleep deprivation in the rat: IV. Paradoxical sleep deprivation. Sleep. 1989;12(1):22–30.CrossRefPubMed Kushida CA, Bergmann BM, Rechtschaffen A. Sleep deprivation in the rat: IV. Paradoxical sleep deprivation. Sleep. 1989;12(1):22–30.CrossRefPubMed
44.
go back to reference Franken P, Dijk DJ, Tobler I, Borbely AA. Sleep deprivation in rats: effects on EEG power spectra, vigilance states, and cortical temperature. Am J Phys. 1991;261(1 Pt 2):R198–208. Franken P, Dijk DJ, Tobler I, Borbely AA. Sleep deprivation in rats: effects on EEG power spectra, vigilance states, and cortical temperature. Am J Phys. 1991;261(1 Pt 2):R198–208.
45.
go back to reference Tobler I, Deboer T, Fischer M. Sleep and sleep regulation in normal and prion protein-deficient mice. J Neurosci. 1997;17(5):1869–79.PubMed Tobler I, Deboer T, Fischer M. Sleep and sleep regulation in normal and prion protein-deficient mice. J Neurosci. 1997;17(5):1869–79.PubMed
46.
go back to reference Longuski PA, Cudillo CA, Stern JJ. Brief communication effects of estradiol on feeding and locomotion in REM deprived rats. Physiol Behav. 1976;16(1):97–9.CrossRefPubMed Longuski PA, Cudillo CA, Stern JJ. Brief communication effects of estradiol on feeding and locomotion in REM deprived rats. Physiol Behav. 1976;16(1):97–9.CrossRefPubMed
49.
50.
51.
go back to reference • Khalyfa A, Carreras A, Almendros I, Hakim F, Gozal D. Sex dimorphism in late gestational sleep fragmentation and metabolic dysfunction in offspring mice. Sleep. 2015;38(4):545–57. https://doi.org/10.5665/sleep.4568. Pre-clinical study reporting that sleep fragementation in pregnant dams significantly increased absolute bodyweight, food intake and visceral and subcutaneous fat in male but not female offspring suggesting that sleep frgamentation during gestation predisposes male but not female offspring towards increased risk of obesity during early life. CrossRefPubMedPubMedCentral • Khalyfa A, Carreras A, Almendros I, Hakim F, Gozal D. Sex dimorphism in late gestational sleep fragmentation and metabolic dysfunction in offspring mice. Sleep. 2015;38(4):545–57. https://​doi.​org/​10.​5665/​sleep.​4568. Pre-clinical study reporting that sleep fragementation in pregnant dams significantly increased absolute bodyweight, food intake and visceral and subcutaneous fat in male but not female offspring suggesting that sleep frgamentation during gestation predisposes male but not female offspring towards increased risk of obesity during early life. CrossRefPubMedPubMedCentral
53.
go back to reference U.S. Department of Health and Human Services. Food and Drug Administration CfDEaRC. Guidance for industry: developing products for weight management (draft guidance) 2007. U.S. Department of Health and Human Services. Food and Drug Administration CfDEaRC. Guidance for industry: developing products for weight management (draft guidance) 2007.
55.
go back to reference • Parrish JB, Teske JA. Acute partial sleep deprivation due to environmental noise increases weight gain by reducing energy expenditure in rodents. Obesity (Silver Spring). 2017;25(1):141–6. https://doi.org/10.1002/oby.21703. Pre-clinical study shows that acute partial sleep disruption due to environmental noise expsoure significantly increases weight gain and reduces total energy expenditure and its components with no effect on food intake, demonstrating that reductions in energy expenditure contribute to weight gain after acute sleep disruption in males. CrossRef • Parrish JB, Teske JA. Acute partial sleep deprivation due to environmental noise increases weight gain by reducing energy expenditure in rodents. Obesity (Silver Spring). 2017;25(1):141–6. https://​doi.​org/​10.​1002/​oby.​21703. Pre-clinical study shows that acute partial sleep disruption due to environmental noise expsoure significantly increases weight gain and reduces total energy expenditure and its components with no effect on food intake, demonstrating that reductions in energy expenditure contribute to weight gain after acute sleep disruption in males. CrossRef
65.
go back to reference • Sampey BP, Vanhoose AM, Winfield HM, Freemerman AJ, Muehlbauer MJ, Fueger PT, et al. Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: comparison to high-fat diet. Obesity (Silver Spring). 2011;19(6):1109–17. https://doi.org/10.1038/oby.2011.18. Pre-clinical study reporting that a cafeteria-style diet causes more negative outcomes (e.g. calorie intake, weight gain, epididymal white adipose tissue mass, macrophage infiltration indicated by corn-like structures and hepatic inflammatory loci) compared to a pelleted high diet diet. CrossRef • Sampey BP, Vanhoose AM, Winfield HM, Freemerman AJ, Muehlbauer MJ, Fueger PT, et al. Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: comparison to high-fat diet. Obesity (Silver Spring). 2011;19(6):1109–17. https://​doi.​org/​10.​1038/​oby.​2011.​18. Pre-clinical study reporting that a cafeteria-style diet causes more negative outcomes (e.g. calorie intake, weight gain, epididymal white adipose tissue mass, macrophage infiltration indicated by corn-like structures and hepatic inflammatory loci) compared to a pelleted high diet diet. CrossRef
66.
go back to reference Rothwell NJ, Stock MJ. A role for insulin in the diet-induced thermogenesis of cafeteria-fed rats. Metabolism. 1981;30(7):673–8.CrossRefPubMed Rothwell NJ, Stock MJ. A role for insulin in the diet-induced thermogenesis of cafeteria-fed rats. Metabolism. 1981;30(7):673–8.CrossRefPubMed
Metadata
Title
Role of Sex and the Environment in Moderating Weight Gain Due to Inadequate Sleep
Authors
Jamie E. Coborn
Monica M. Houser
Claudio E. Perez-Leighton
Jennifer A. Teske
Publication date
01-12-2017
Publisher
Springer US
Published in
Current Obesity Reports / Issue 4/2017
Electronic ISSN: 2162-4968
DOI
https://doi.org/10.1007/s13679-017-0290-7

Other articles of this Issue 4/2017

Current Obesity Reports 4/2017 Go to the issue

Metabolism (CJ Billington, Section Editor)

Brown Adipose Tissue: an Update on Recent Findings

Metabolism (CJ Billington, Section Editor)

What Twin Studies Tell Us About Brain Responses to Food Cues

The Obesity Epidemic: Causes and Consequences (A Cameron and K Backholer, Section Editors)

Ultra-processed Food Intake and Obesity: What Really Matters for Health—Processing or Nutrient Content?

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.