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Diabetologia
Published in: Diabetologia 11/2016

01-11-2016 | Letter

Role of glycogen metabolism in pancreatic islet beta cell function

Author: Willy J. Malaisse

Published in: Diabetologia | Issue 11/2016

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Excerpt

To the Editor: In light of the recent publication in Diabetologia by Mir-Coll et al, entitled ‘Genetic models rule out a major role of beta cell glycogen in the control of glucose homeostasis’ [1], this letter aims to remind readers of evidence supporting a major role for beta cell glycogen accumulation in perturbation of glucose-stimulated insulin secretion observed in non-insulin dependent diabetes [2]. …
Literature
1.
Mir-Coll J, Duran J, Slebe F et al (2016) Genetic models rule out a major role of beta cell glycogen in the control of glucose homeostasis. Diabetologia 59:1012–1020CrossRefPubMed
2.
Malaisse WJ (1991) Physiology of insulin secretion and its alteration in diabetes: the concept of glucotoxicity. In: Andreani D, Gueriguian JL, Striker GE (eds) Diabetic complications: epidemiology and pathogenetic mechanisms. Raven Press, New York, pp 3–23
3.
4.
Malaisse WJ, Sener A, Koser M, Ravazzola M, Malaisse-Lagae F (1977) The stimulus-secretion coupling of glucose-induced insulin release. Insulin release due to glycogenolysis in glucose-deprived islets. Biochem J 164:447–454CrossRefPubMedPubMedCentral
5.
Gomis R, Novials A, Coves MJ, Casamitjana R, Malaisse WJ (1989) Suppression by insulin treatment of glucose-induced inhibition of insulin release in non-insulin-dependent diabetics. Diabetes Res Clin Pract 6:191–198CrossRefPubMed
6.
Marynissen G, Leclercq-Meyer V, Sener A, Malaisse WJ (1990) Perturbation of pancreatic islet function in glucose-infused rats. Metabolism 39:87–95CrossRefPubMed
7.
Rovira A, Garrotte FJ, Valverde I, Malaisse WJ (1987) Anomeric specificity of glucose-induced insulin release in normal and diabetic subjects. Diabetes Res 5:119–124PubMed
8.
Niki A, Niki H, Niki I, Kunoh Y (1988) Insulin release by glucose anomers in a rat model of non-insulin-dependent diabetes. Diabetologia 31:65–67PubMed
9.
Leclercq-Meyer V, Marchand J, Malaisse WJ (1987) Alteration of the insulin secretory response to D-glucose anomers in diabetic BB rats. Med Sci Res 15:1535–1536
10.
Fichaux F, Marchand J, Yaylali B, Leclercq-Meyer V, Catala J, Malaisse WJ (1991) Altered anomeric specificity of glucose-induced insulin release in rabbits with duct-ligated pancreas. Int J Pancreatol 8:151–167PubMed
11.
Leclercq-Meyer V, Marchand J, Malaisse WJ (1991) Attenuated anomeric difference of glucose-induced insulin release in the perfused pancreas of diazoxide-treated rats. Horm Metab Res 23:257–261CrossRefPubMed
12.
Malaisse WJ, Marynissen G, Sener A (1992) Possible role of glycogen accumulation in B cell glucotoxicity. Metabolism 41:814–819CrossRefPubMed
13.
Malaisse WJ, Maggetto C, Leclercq-Meyer V, Sener A (1993) Interference of glycogenolysis with glycolysis in pancreatic islets from glucose-infused rats. J Clin Invest 91:432–436CrossRefPubMedPubMedCentral
14.
Bollen M, Malaisse-Lagae F, Malaisse W, Stalmans W (1990) The interaction of phosphorylase a with D-glucose displays α-stereospecificity. Biochim Biophys Acta 1038:141–145CrossRefPubMed
15.
Andrikopoulos S, Blair AR, Deluca N, Fam BC, Proietto J (2008) Evaluating the glucose tolerance test in mic. Am J Physiol Endocrinol Metab 295:E1323–E1332CrossRefPubMed
Metadata
Title
Role of glycogen metabolism in pancreatic islet beta cell function
Author
Willy J. Malaisse
Publication date
01-11-2016
Publisher
Springer Berlin Heidelberg
Published in
Diabetologia / Issue 11/2016
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-016-4092-3

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