Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Critical Care
Published in: Critical Care 6/2009

01-12-2009 | Letter

Role of chlorhexidine gluconate in ventilator-associated pneumonia prevention strategies in ICU patients: where are we headed?

Authors: Tanmay S Panchabhai, Neha S Dangayach

Published in: Critical Care | Issue 6/2009

Login to get access

Excerpt

We read with interest the recent study by Scannapieco and colleagues [1], which concluded that twice-daily oral rinse with 0.12% chlorhexidine failed to reduce the number of potential respiratory pathogens in dental plaque, mortality, the incidence of ventilator-associated pneumonia (VAP), the length of intensive care unit (ICU) stay and the duration of mechanical ventilation in trauma ICU patients. …
Literature
1.
Scannapieco FA, Yu J, Raghavendran K, Vacanti A, Owens SI, Wood K, Mulotte JM: A randomized trial of chlorhexidine gluconate on oral bacterial pathogens in mechanically ventilated patients. Crit Care 2009, 13: R117. 10.1186/cc7967PubMedCentralCrossRefPubMed
2.
Panchabhai TS, Dangayach NS, Krishnan A, Kothari VM, Karnad DR: Oropharyngeal cleansing with 0.2% chlorhexidine for prevention of nosocomial pneumonia in critically ill patients: an open label randomized trial with 0.01% potassium permanganate as control. Chest 2009, 135: 1150-1156. 10.1378/chest.08-1321CrossRefPubMed
3.
Tantipong H, Morkchareonpong C, Jaiyindee S, Thamlikitkul V: Randomized controlled trial and meta-analysis of oral decontamination with 2% chlorhexidine solution for the prevention of ventilator-associated pneumonia. Infect Control Hosp Epidemiol 2008, 29: 131-136. 10.1086/526438CrossRefPubMed
4.
Sekino S, Ramberg P, Uzel NG, Socranksky S, Lidhe J: The effect of a chlorhexidine regimen on de novo plaque formation. J Clin Periodontol 2004, 31: 609-614. 10.1111/j.1600-051X.2004.00526.xCrossRefPubMed
5.
Pobo A, Lisboa T, Rodriguez A, Sloe R, Margret M, Trefler S, Gomez F, Rello J: A randomized trial of dental brushing for preventing ventilator associated pneumonia. Chest 2009, 136: 433-439. 10.1378/chest.09-0706CrossRefPubMed
6.
Munro CL, Grap MJ, Jones DJ, McClish DK, Sessler CN: Chlorhexidine, toothbrushing and preventing ventilator-associated pneumonia in critically ill adults. Am J Crit Care 2009, 18: 428-437. 10.4037/ajcc2009792PubMedCentralCrossRefPubMed
Metadata
Title
Role of chlorhexidine gluconate in ventilator-associated pneumonia prevention strategies in ICU patients: where are we headed?
Authors
Tanmay S Panchabhai
Neha S Dangayach
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Critical Care / Issue 6/2009
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc8165

Other articles of this Issue 6/2009

Critical Care 6/2009 Go to the issue

Research

The incidence of sub-optimal sedation in the ICU: a systematic review

Research

Global end-diastolic volume acquired by transpulmonary thermodilution depends on age and gender in awake and spontaneously breathing patients

Commentary

Host immune response in sepsis due to ventilator-associated pneumonia: how is it different?

Commentary

Recently published papers: Renal support in acute kidney injury - is low dose the new high dose?

Review

Clinical review: Primary influenza viral pneumonia

Commentary

β2 adrenergic agonists in acute lung injury? The heart of the matter