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Published in: Critical Care 6/2009

01-12-2009 | Commentary

Host immune response in sepsis due to ventilator-associated pneumonia: how is it different?

Author: Eirini Christaki

Published in: Critical Care | Issue 6/2009

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Abstract

Current evidence regarding potentially different host response mechanisms in sepsis according to the type of initiating infection is sporadic. It is possible that alterations in cell populations, variations in effector molecules, and the degree of apoptosis differ between sepsis caused by ventilator-associated pneumonia (VAP) and non-VAP sepsis. VAP is one of the most common infections and leading causes of sepsis in the intensive care unit, and mortality remains high. A better understanding of the unique pathophysiologic features of VAP is needed in order to develop interventions that target those specific pathways.
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Metadata
Title
Host immune response in sepsis due to ventilator-associated pneumonia: how is it different?
Author
Eirini Christaki
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Critical Care / Issue 6/2009
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc8174

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