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Published in: Aesthetic Plastic Surgery 2/2020

01-04-2020 | Rhinoplasty | Original Article

Concentrated Growth Factors Extracted from Blood Plasma Used to Repair Nasal Septal Mucosal Defect After Rhinoplasty

Authors: Qi-Ming Zhao, Jie Gao, Xiao-xiang Huang, Xiao-ping Chen, Xin Wang

Published in: Aesthetic Plastic Surgery | Issue 2/2020

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Abstract

Background

To assess preliminarily the effect of concentrated growth factor (CGF) for repair of nasal septal mucosal defect after rhinoplasty.

Methods

Ten women with mucosal defects of the nasal septum were enrolled from May 2017 to May 2018. Liquid and gel CGF was prepared from each patient’s blood sample using a Medifuge system, including benchtop centrifuge. After debridement of the defect, the prepared liquid CGF was injected around the wound, and a membranous CGF film was applied to the surface. Vaseline gauze was used to pack the nostrils. All patients were treated with CGF at intervals from 3 to 5 days.

Results

After 3 to 12 treatments, all the patients achieved successful repair of the nasal septal mucosal defect, with good appearance and function. During a follow-up of 3 to 6 months, no recurrence was observed.

Conclusion

CGF appeared to have great curative effect for patients with nasal septal mucosal defects after rhinoplasty. The procedure was easy to perform and should be considered worthwhile in clinical practice.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
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Metadata
Title
Concentrated Growth Factors Extracted from Blood Plasma Used to Repair Nasal Septal Mucosal Defect After Rhinoplasty
Authors
Qi-Ming Zhao
Jie Gao
Xiao-xiang Huang
Xiao-ping Chen
Xin Wang
Publication date
01-04-2020
Publisher
Springer US
Published in
Aesthetic Plastic Surgery / Issue 2/2020
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-019-01474-7

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