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Published in: Clinical Rheumatology 1/2015

Open Access 01-03-2015 | Review Article

Rheumatoid arthritis in Latin America: the importance of an early diagnosis

Authors: Licia Maria Henrique da Mota, Claiton Viegas Brenol, Penelope Palominos, Geraldo da Rocha Castelar Pinheiro

Published in: Clinical Rheumatology | Special Issue 1/2015

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Abstract

The generalization of the early rheumatoid arthritis (ERA) concept and the existence of a window of therapeutic opportunity—a time span in which the institution of a proper therapeutic method for the disease would determine clinical improvement—have set the notion that early diagnosis and treatment may modify the course of the disease. Although in several regions of the world, especially in North America and Europe, since the year 2000, a significant reduction in diagnostic delay was observed in cohorts of patients with rheumatoid arthritis (RA), probably reflecting a stronger awareness of the importance of early diagnosis, this is not a reality in Latin America (LA). LA is a region of great economic inequality, with disparities in access to the public healthcare system and limited access to private medicine, being widely difficult to obtain a specialized medical evaluation in both scenarios. This paper aims to briefly review the main difficulties in the management of ERA in LA, based on the review of the literature, on the evaluation of a survey conducted among 214 rheumatologists of LA, members of Pan-American League of Associations for Rheumatology (PANLAR) and the experience of the authors. The paper also aims to propose solutions to the difficulties in managing ERA in LA.
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Literature
1.
go back to reference Aletaha D, Neogi T, Silman AJ et al (2010) 2010 rheumatoid arthritis classification criteria. An American College of Rheumatology/European League against rheumatism collaborative initiative. Arthritis Rheum 62:2569–2581. doi:10.1002/art.27584 CrossRefPubMed Aletaha D, Neogi T, Silman AJ et al (2010) 2010 rheumatoid arthritis classification criteria. An American College of Rheumatology/European League against rheumatism collaborative initiative. Arthritis Rheum 62:2569–2581. doi:10.​1002/​art.​27584 CrossRefPubMed
2.
go back to reference van Nies JA, Tsonaka R, Gaujoux-Viala C, Fautrel B, van der Helm-van Mil AH (2015) Evaluating relationships between symptom duration and persistence of rheumatoid arthritis: does a window of opportunity exist? Results on the leiden early arthritis clinic and ESPOIR cohorts. Ann Rheum Dis. doi:10.1136/annrheumdis-2014-206047 van Nies JA, Tsonaka R, Gaujoux-Viala C, Fautrel B, van der Helm-van Mil AH (2015) Evaluating relationships between symptom duration and persistence of rheumatoid arthritis: does a window of opportunity exist? Results on the leiden early arthritis clinic and ESPOIR cohorts. Ann Rheum Dis. doi:10.​1136/​annrheumdis-2014-206047
3.
go back to reference van der Horst-Bruinsma IE, Speyer I, Visser H, Breedvelt FC, Hazes GM (1998) Diagnosis and course of early-onset arthritis: results of a special early arthritis clinic compared to routine patient care. Br J Rheumatol 37:1084–1088CrossRefPubMed van der Horst-Bruinsma IE, Speyer I, Visser H, Breedvelt FC, Hazes GM (1998) Diagnosis and course of early-onset arthritis: results of a special early arthritis clinic compared to routine patient care. Br J Rheumatol 37:1084–1088CrossRefPubMed
4.
go back to reference Nell VPK, Machold KP, Eberl G, Stamm TA, Uffmann M, Smolen JS (2004) Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology 43:906–914CrossRefPubMed Nell VPK, Machold KP, Eberl G, Stamm TA, Uffmann M, Smolen JS (2004) Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology 43:906–914CrossRefPubMed
5.
go back to reference Nam JL, Ramiro S, Gaujoux-Viala C, Takase K, Leon-Garcia M, Emery P, Gossec L, Landewe R, Smolen JS, Buch MH (2014) Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis 73(3):516–528. doi:10.1136/annrheumdis-2013-204577 CrossRefPubMed Nam JL, Ramiro S, Gaujoux-Viala C, Takase K, Leon-Garcia M, Emery P, Gossec L, Landewe R, Smolen JS, Buch MH (2014) Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis 73(3):516–528. doi:10.​1136/​annrheumdis-2013-204577 CrossRefPubMed
6.
go back to reference Majithia V, Geraci SA (2007) Rheumatoid arthritis: diagnosis and management. Am J Med 120:936–939CrossRefPubMed Majithia V, Geraci SA (2007) Rheumatoid arthritis: diagnosis and management. Am J Med 120:936–939CrossRefPubMed
7.
go back to reference van Nies JA, Brouwer E, van Gaalen FA, Allaart CF, Huizinga TW, Posthumus MD, van der Helm-van Mil AH (2013) Improved early identification of arthritis: evaluating the efficacy of early arthritis recognition clinics. Ann Rheum Dis 72(8):1295–1301. doi:10.1136/annrheumdis-2012-202289 CrossRefPubMed van Nies JA, Brouwer E, van Gaalen FA, Allaart CF, Huizinga TW, Posthumus MD, van der Helm-van Mil AH (2013) Improved early identification of arthritis: evaluating the efficacy of early arthritis recognition clinics. Ann Rheum Dis 72(8):1295–1301. doi:10.​1136/​annrheumdis-2012-202289 CrossRefPubMed
8.
go back to reference Cabral D, Katz JN, Weinblatt ME, Ting G, Avorn J, Solomon DH (2005) Development and assessment of indicators of rheumatoid arthritis severity: results of a Delphi panel. Arthritis Rheum 53:61–66CrossRefPubMed Cabral D, Katz JN, Weinblatt ME, Ting G, Avorn J, Solomon DH (2005) Development and assessment of indicators of rheumatoid arthritis severity: results of a Delphi panel. Arthritis Rheum 53:61–66CrossRefPubMed
9.
10.
11.
go back to reference Uhlig T, Heiberg T, Mowinckel P et al (2008) Rheumatoid arthritis is milder in the new millennium: health status in patients with rheumatoid arthritis 1994–2004. Ann Rheum Dis 67:1710–1715CrossRefPubMed Uhlig T, Heiberg T, Mowinckel P et al (2008) Rheumatoid arthritis is milder in the new millennium: health status in patients with rheumatoid arthritis 1994–2004. Ann Rheum Dis 67:1710–1715CrossRefPubMed
12.
go back to reference Raza K, Stack R, Kumar K et al (2011) Delays in assessment of patients with rheumatoid arthritis: variations across Europe. Ann Rheum Dis 70:1822–1825CrossRefPubMed Raza K, Stack R, Kumar K et al (2011) Delays in assessment of patients with rheumatoid arthritis: variations across Europe. Ann Rheum Dis 70:1822–1825CrossRefPubMed
15.
go back to reference Chopra A, Abdel-Nasser A (2008) Epidemiology of rheumatic musculoskeletal disorders in the developing world. Best Pract Res Clin Rheumatol 22:583–604CrossRefPubMed Chopra A, Abdel-Nasser A (2008) Epidemiology of rheumatic musculoskeletal disorders in the developing world. Best Pract Res Clin Rheumatol 22:583–604CrossRefPubMed
16.
go back to reference Chopra A (2012) The WHO ILAR COPCORD Latin America: consistent with the world and setting a new perspective. J Clin Rheumatol 18:1679 Chopra A (2012) The WHO ILAR COPCORD Latin America: consistent with the world and setting a new perspective. J Clin Rheumatol 18:1679
18.
go back to reference Bennett K, Cardiel MH, Ferraz MB, Riedemann P, Goldsmith CH, Tugwell P (1997) Community screening for rheumatic disorder: cross cultural adaptation and screening characteristics of the COPCORD core questionnaire in Brazil, Chile, and Mexico. The PANLAR-COPCORD working group. Pan American League of Associations for rheumatology. community oriented programme for the control of rheumatic disease. J Rheumatol 24(1):160–168PubMed Bennett K, Cardiel MH, Ferraz MB, Riedemann P, Goldsmith CH, Tugwell P (1997) Community screening for rheumatic disorder: cross cultural adaptation and screening characteristics of the COPCORD core questionnaire in Brazil, Chile, and Mexico. The PANLAR-COPCORD working group. Pan American League of Associations for rheumatology. community oriented programme for the control of rheumatic disease. J Rheumatol 24(1):160–168PubMed
19.
go back to reference Peláez-Ballestas I, Sanin LH, Moreno-Montoya J, Alvarez-Nemegyei J, Burgos-Vargas R, Garza-Elizondo M, Rodríguez-Amado J, Goycochea-Robles MV, Madariaga M, Zamudio J, Santana N, Cardiel MH, Grupo de Estudio Epidemiológico de Enfermedades Músculo Articulares (GEEMA) (2011) Epidemiology of the rheumatic diseases in Mexico. A study of 5 regions based on the COPCORD methodology. J Rheumatol Suppl 86:3–8. doi:10.3899/jrheum.100951, Erratum in: J Rheumatol Suppl. 2011 Mar;38(3):585CrossRefPubMed Peláez-Ballestas I, Sanin LH, Moreno-Montoya J, Alvarez-Nemegyei J, Burgos-Vargas R, Garza-Elizondo M, Rodríguez-Amado J, Goycochea-Robles MV, Madariaga M, Zamudio J, Santana N, Cardiel MH, Grupo de Estudio Epidemiológico de Enfermedades Músculo Articulares (GEEMA) (2011) Epidemiology of the rheumatic diseases in Mexico. A study of 5 regions based on the COPCORD methodology. J Rheumatol Suppl 86:3–8. doi:10.​3899/​jrheum.​100951, Erratum in: J Rheumatol Suppl. 2011 Mar;38(3):585CrossRefPubMed
20.
go back to reference Rodriguez-Amado J, Peláez-Ballestas I, Sanin LH, Esquivel-Valerio JA, Burgos-Vargas R, Pérez-Barbosa L, Riega-Torres J, Garza-Elizondo MA (2011) Epidemiology of rheumatic diseases. A community-based study in urban and rural populations in the state of Nuevo Leon, Mexico. J Rheumatol Suppl 86:9–14. doi:10.3899/jrheum.100952 CrossRefPubMed Rodriguez-Amado J, Peláez-Ballestas I, Sanin LH, Esquivel-Valerio JA, Burgos-Vargas R, Pérez-Barbosa L, Riega-Torres J, Garza-Elizondo MA (2011) Epidemiology of rheumatic diseases. A community-based study in urban and rural populations in the state of Nuevo Leon, Mexico. J Rheumatol Suppl 86:9–14. doi:10.​3899/​jrheum.​100952 CrossRefPubMed
21.
go back to reference Senna ER, De Barros AL, Silva EO, Costa IF, Pereira LV, Ciconelli RM, Ferraz MB (2004) Prevalence of rheumatic diseases in Brazil: a study using the COPCORD approach. J Rheumatol 31(3):594–597PubMed Senna ER, De Barros AL, Silva EO, Costa IF, Pereira LV, Ciconelli RM, Ferraz MB (2004) Prevalence of rheumatic diseases in Brazil: a study using the COPCORD approach. J Rheumatol 31(3):594–597PubMed
22.
go back to reference Pereira AM, Valim V, Zandonade E, Ciconelli RM (2009) Prevalence of musculoskeletal manifestations in the adult Brazilian population: a study using copcord questionnaires. Clin Exp Rheumatol 27(1):42–46PubMed Pereira AM, Valim V, Zandonade E, Ciconelli RM (2009) Prevalence of musculoskeletal manifestations in the adult Brazilian population: a study using copcord questionnaires. Clin Exp Rheumatol 27(1):42–46PubMed
23.
go back to reference Reyes-Llerena GA, Guibert-Toledano M, Penedo-Coello A, Pérez-Rodríguez A, Baez-Dueñas RM, Charnicharo-Vidal R, Cardiel MH (2009) Community-based study to estimate prevalence and burden of illness of rheumatic diseases in Cuba: a COPCORD study. J Clin Rheumatol 15(2):51–55. doi:10.1097/RHU.0b013e31819b61cb CrossRefPubMed Reyes-Llerena GA, Guibert-Toledano M, Penedo-Coello A, Pérez-Rodríguez A, Baez-Dueñas RM, Charnicharo-Vidal R, Cardiel MH (2009) Community-based study to estimate prevalence and burden of illness of rheumatic diseases in Cuba: a COPCORD study. J Clin Rheumatol 15(2):51–55. doi:10.​1097/​RHU.​0b013e31819b61cb​ CrossRefPubMed
24.
go back to reference Aletaha D, Eberl G, Nell VP, Machold KP, Smolen JS (2004) Attitudes to early rheumatoid arthritis: changing patterns. Results of a survey. Ann Rheum Dis 63:1269–1275PubMedCentralCrossRefPubMed Aletaha D, Eberl G, Nell VP, Machold KP, Smolen JS (2004) Attitudes to early rheumatoid arthritis: changing patterns. Results of a survey. Ann Rheum Dis 63:1269–1275PubMedCentralCrossRefPubMed
25.
go back to reference Pinheiro GRC, Rebello MA, Andrade DO et al (2003) Investigating the role of rheumatologists in musculoskeletal disease management in the city of Rio de Janeiro. Ann Rheum Dis 62:534CrossRef Pinheiro GRC, Rebello MA, Andrade DO et al (2003) Investigating the role of rheumatologists in musculoskeletal disease management in the city of Rio de Janeiro. Ann Rheum Dis 62:534CrossRef
26.
go back to reference Xibillé-Friedmann D, Mondragón-Flores V, Horcasitas de la Rosa C (2006) Criteria used by primary care physicians for the diagnosis and referral to a rheumatologist of patients with rheumatoid arthritis. Reumatol Clin 2(5):235–238CrossRefPubMed Xibillé-Friedmann D, Mondragón-Flores V, Horcasitas de la Rosa C (2006) Criteria used by primary care physicians for the diagnosis and referral to a rheumatologist of patients with rheumatoid arthritis. Reumatol Clin 2(5):235–238CrossRefPubMed
27.
go back to reference Lard LR, Visser H, Speyer I, vander Horst-Bruinsma IE, Zwinderman AH, Breedveld FC et al (2001) Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies. Am J Med 111(6):446–451CrossRefPubMed Lard LR, Visser H, Speyer I, vander Horst-Bruinsma IE, Zwinderman AH, Breedveld FC et al (2001) Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies. Am J Med 111(6):446–451CrossRefPubMed
28.
go back to reference Nell VP, Machold KP, Eberl G, Stamm TA, Uffmann M, Smolen JS (2004) Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology (Oxford) 43(7):906–914CrossRef Nell VP, Machold KP, Eberl G, Stamm TA, Uffmann M, Smolen JS (2004) Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology (Oxford) 43(7):906–914CrossRef
29.
go back to reference Bosello S, Fedele AL, Peluso G, Gremese E, Tolusso B, Ferraccioli G (2011) Very early rheumatoid arthritis is the major predictor of major outcomes: clinical ACR remission and radiographic non-progression. Ann Rheum Dis 70(7):1292–1295PubMedCentralCrossRefPubMed Bosello S, Fedele AL, Peluso G, Gremese E, Tolusso B, Ferraccioli G (2011) Very early rheumatoid arthritis is the major predictor of major outcomes: clinical ACR remission and radiographic non-progression. Ann Rheum Dis 70(7):1292–1295PubMedCentralCrossRefPubMed
30.
go back to reference Verpoort KN, van Dongen H, Allaart CF, Toes RE, Breedveld FC, Huizinga TW (2004) Undifferentiated arthritis—disease course assessed in several inception cohorts. Clin Exp Rheumatol 5(Suppl 35):12–17 Verpoort KN, van Dongen H, Allaart CF, Toes RE, Breedveld FC, Huizinga TW (2004) Undifferentiated arthritis—disease course assessed in several inception cohorts. Clin Exp Rheumatol 5(Suppl 35):12–17
31.
go back to reference van Aken J, van Dongen H, le Cessie S, Allaart CF, Breedveld FC, Huizinga TW (2006) Comparison of long term outcome of patients with rheumatoid arthritis presenting with undifferentiated arthritis or with rheumatoid arthritis: an observational cohort study. Ann Rheum Dis 65(1):20–25PubMedCentralCrossRefPubMed van Aken J, van Dongen H, le Cessie S, Allaart CF, Breedveld FC, Huizinga TW (2006) Comparison of long term outcome of patients with rheumatoid arthritis presenting with undifferentiated arthritis or with rheumatoid arthritis: an observational cohort study. Ann Rheum Dis 65(1):20–25PubMedCentralCrossRefPubMed
32.
go back to reference Criswell LA, Such CL, Yelin EH (1997) Differences in the use of second-line agents and prednisone for treatment of rheumatoid arthritis by rheumatologists and non-rheumatologists. J Rheumatol 24(12):2283–2290PubMed Criswell LA, Such CL, Yelin EH (1997) Differences in the use of second-line agents and prednisone for treatment of rheumatoid arthritis by rheumatologists and non-rheumatologists. J Rheumatol 24(12):2283–2290PubMed
33.
go back to reference Lacaille D, Anis AH, Guh DP, Esdaile JM (2005) Gaps in care for rheumatoid arthritis: a population study. Arthritis Rheum 53(2):241–248CrossRefPubMed Lacaille D, Anis AH, Guh DP, Esdaile JM (2005) Gaps in care for rheumatoid arthritis: a population study. Arthritis Rheum 53(2):241–248CrossRefPubMed
34.
go back to reference Rat AC, Henegariu V, Boissier MC (2004) Do primary care physicians have a place in the management of rheumatoid arthritis? Joint Bone Spine 71(3):190–197CrossRefPubMed Rat AC, Henegariu V, Boissier MC (2004) Do primary care physicians have a place in the management of rheumatoid arthritis? Joint Bone Spine 71(3):190–197CrossRefPubMed
35.
go back to reference Solomon DH, Bates DW, Panush RS, Katz JN (1997) Costs, outcomes, and patient satisfaction by provider type for patients with rheumatic and musculoskeletal conditions: a critical review of the literature and proposed methodologic standards. Ann Intern Med 127(1):52–60CrossRefPubMed Solomon DH, Bates DW, Panush RS, Katz JN (1997) Costs, outcomes, and patient satisfaction by provider type for patients with rheumatic and musculoskeletal conditions: a critical review of the literature and proposed methodologic standards. Ann Intern Med 127(1):52–60CrossRefPubMed
36.
go back to reference Emery P, Breedveld FC, Dougados M, Kalden JR, Schiff MH, Smolen JS (2002) Early referral recommendation for newly diagnosed rheumatoid arthritis: evidence based development of a clinical guide. Ann Rheum Dis 61(4):290–297PubMedCentralCrossRefPubMed Emery P, Breedveld FC, Dougados M, Kalden JR, Schiff MH, Smolen JS (2002) Early referral recommendation for newly diagnosed rheumatoid arthritis: evidence based development of a clinical guide. Ann Rheum Dis 61(4):290–297PubMedCentralCrossRefPubMed
37.
go back to reference Hernandez-Garcia C, Vargas E, Abasolo L, Lajas C, Bellajdell B, Morado IC et al (2000) Lag time between onset of symptoms and access to rheumatology care and DMARD therapy in a cohort of patients with rheumatoid arthritis. J Rheumatol 27(10):2323–2328PubMed Hernandez-Garcia C, Vargas E, Abasolo L, Lajas C, Bellajdell B, Morado IC et al (2000) Lag time between onset of symptoms and access to rheumatology care and DMARD therapy in a cohort of patients with rheumatoid arthritis. J Rheumatol 27(10):2323–2328PubMed
38.
go back to reference Cardiel MH, Latin American Rheumatology Associations of the Pan-American League of Associations for Rheumatology (PANLAR), Grupo Latino Americano de Estudio de Artritis Reumatoide (GLADAR) (2006) First Latin American position paper on the pharmacological treatment of rheumatoid arthritis. Rheumatology (Oxford) 45(Suppl:i):7–22 Cardiel MH, Latin American Rheumatology Associations of the Pan-American League of Associations for Rheumatology (PANLAR), Grupo Latino Americano de Estudio de Artritis Reumatoide (GLADAR) (2006) First Latin American position paper on the pharmacological treatment of rheumatoid arthritis. Rheumatology (Oxford) 45(Suppl:i):7–22
39.
go back to reference Villeneuve E, Nam JL, Bell MJ, Deighton CM, Felson DT, Hazes JM et al (2013) A systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Ann Rheum Dis 72(1):13–22CrossRefPubMed Villeneuve E, Nam JL, Bell MJ, Deighton CM, Felson DT, Hazes JM et al (2013) A systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Ann Rheum Dis 72(1):13–22CrossRefPubMed
40.
go back to reference Massardo L, Suárez-Almazor ME, Cardiel MH, Nava A, Levy RA, Laurindo I, Soriano ER, Acevedo-Vázquez E, Millán A, Pineda-Villaseñor C, Galarza-Maldonado C, Caballero-Uribe CV, Espinosa-Morales R, Pons-Estel BA (2009) Management of patients with rheumatoid arthritis in Latin America: a consensus position paper from Pan-American League of Associations of Rheumatology and Grupo Latino Americano De Estudio De Artritis Reumatoide. J Clin Rheumatol 15(4):203–210. doi:10.1097/RHU.0b013e3181a90cd8 CrossRefPubMed Massardo L, Suárez-Almazor ME, Cardiel MH, Nava A, Levy RA, Laurindo I, Soriano ER, Acevedo-Vázquez E, Millán A, Pineda-Villaseñor C, Galarza-Maldonado C, Caballero-Uribe CV, Espinosa-Morales R, Pons-Estel BA (2009) Management of patients with rheumatoid arthritis in Latin America: a consensus position paper from Pan-American League of Associations of Rheumatology and Grupo Latino Americano De Estudio De Artritis Reumatoide. J Clin Rheumatol 15(4):203–210. doi:10.​1097/​RHU.​0b013e3181a90cd8​ CrossRefPubMed
41.
go back to reference Massardo L, Pons-Estel BA, Wojdyla D, Cardiel MH, Galarza-Maldonado CM, Sacnun MP, Soriano ER, Laurindo IM, Acevedo-Vásquez EM, Caballero-Uribe CV, Padilla O, Guibert-Toledano ZM, da Mota LM, Montufar RA, Lino-Pérez L, Díaz-Coto JF, Achurra-Castillo AF, Hernández JA, Esteva-Spinetti MH, Ramírez LA, Pineda C, Furst DE (2012) Early rheumatoid arthritis in Latin America: low socioeconomic status related to high disease activity at baseline. Arthritis Care Res 64(8):1135–1143. doi:10.1002/acr.21680 Massardo L, Pons-Estel BA, Wojdyla D, Cardiel MH, Galarza-Maldonado CM, Sacnun MP, Soriano ER, Laurindo IM, Acevedo-Vásquez EM, Caballero-Uribe CV, Padilla O, Guibert-Toledano ZM, da Mota LM, Montufar RA, Lino-Pérez L, Díaz-Coto JF, Achurra-Castillo AF, Hernández JA, Esteva-Spinetti MH, Ramírez LA, Pineda C, Furst DE (2012) Early rheumatoid arthritis in Latin America: low socioeconomic status related to high disease activity at baseline. Arthritis Care Res 64(8):1135–1143. doi:10.​1002/​acr.​21680
42.
go back to reference Cardiel MH, Pons-Estel BA, Sacnun MP, Wojdyla D, Saurit V, Marcos JC, Pinto MR, Cordeiro de Azevedo AB, da Silveira IG, Radominski SC, Ximenes AC, Massardo L, Ballesteros F, Rojas-Villarraga A, Oñate RV, Hernandez MP, Esquivel-Valerio JA, García-De La Torre I, Khoury VJ, Millán A, Soriano ER, GLADAR (2012) Treatment of early rheumatoid arthritis in a multinational inception cohort of Latin American patients: the GLADAR experience. J Clin Rheumatol 18(7):327–335. doi:10.1097/RHU.0b013e31826d6610 CrossRefPubMed Cardiel MH, Pons-Estel BA, Sacnun MP, Wojdyla D, Saurit V, Marcos JC, Pinto MR, Cordeiro de Azevedo AB, da Silveira IG, Radominski SC, Ximenes AC, Massardo L, Ballesteros F, Rojas-Villarraga A, Oñate RV, Hernandez MP, Esquivel-Valerio JA, García-De La Torre I, Khoury VJ, Millán A, Soriano ER, GLADAR (2012) Treatment of early rheumatoid arthritis in a multinational inception cohort of Latin American patients: the GLADAR experience. J Clin Rheumatol 18(7):327–335. doi:10.​1097/​RHU.​0b013e31826d6610​ CrossRefPubMed
43.
go back to reference Marcos J, Waimann C, Dal Pra F, Hogrefe J, Retamozo S, Caeiro F, Casalla L, Benegas M, Rillo O, Spindler A, Berman H, Berman A, Secco A, García Salinas R, Catalán Pellet A, Ceccato F, Paira S, Marcos JC, Maldonado Cocco JA, Citera G, CONAART (Consorcio Argentino de Artritis Temprana–Argentine Consortium for Early Arthritis) (2011) General characteristics of an early arthritis cohort in Argentina. Rheumatology (Oxford) 50(1):110–116. doi:10.1093/rheumatology/keq220 CrossRef Marcos J, Waimann C, Dal Pra F, Hogrefe J, Retamozo S, Caeiro F, Casalla L, Benegas M, Rillo O, Spindler A, Berman H, Berman A, Secco A, García Salinas R, Catalán Pellet A, Ceccato F, Paira S, Marcos JC, Maldonado Cocco JA, Citera G, CONAART (Consorcio Argentino de Artritis Temprana–Argentine Consortium for Early Arthritis) (2011) General characteristics of an early arthritis cohort in Argentina. Rheumatology (Oxford) 50(1):110–116. doi:10.​1093/​rheumatology/​keq220 CrossRef
44.
go back to reference Haye Salinas MJ, Retamozo S, Alvarez AC, Maldonado Ficco H, Dal Pra F, Citera G, Benegas M, Chaparro Del Moral R, Rillo O, Secco A, Marino Claverie L, Catalan Pellet A, Marcos J, García MA, Marcos JC, Barbaglia A, Bellomio V, Berman A, Quiroz C, Soriano ER, Ceccato F, Paira S, Vazquez D, Juarez VR, Velozo EJ, Salvatierra G, Caeiro F (2014) Effects of cigarette smoking on early arthritis: a cross-sectional study-data from the Argentine Consortium for Early Arthritis (CONAART). Rheumatol Int 35(5):855–859CrossRefPubMed Haye Salinas MJ, Retamozo S, Alvarez AC, Maldonado Ficco H, Dal Pra F, Citera G, Benegas M, Chaparro Del Moral R, Rillo O, Secco A, Marino Claverie L, Catalan Pellet A, Marcos J, García MA, Marcos JC, Barbaglia A, Bellomio V, Berman A, Quiroz C, Soriano ER, Ceccato F, Paira S, Vazquez D, Juarez VR, Velozo EJ, Salvatierra G, Caeiro F (2014) Effects of cigarette smoking on early arthritis: a cross-sectional study-data from the Argentine Consortium for Early Arthritis (CONAART). Rheumatol Int 35(5):855–859CrossRefPubMed
45.
go back to reference da Mota LM, Laurindo IM, dos Santos Neto LL (2010) Demographic and clinical characteristics of a cohort of patients with early rheumatoid arthritis. Rev Bras Reumatol 50(3):235–248CrossRefPubMed da Mota LM, Laurindo IM, dos Santos Neto LL (2010) Demographic and clinical characteristics of a cohort of patients with early rheumatoid arthritis. Rev Bras Reumatol 50(3):235–248CrossRefPubMed
46.
go back to reference da Mota LM, Dos Santos Neto LL, Oliveira AC, Pereira IA, Burlingame RW, Ménard HA (2012) Laurindo IM (2012) Baseline HAQ and SF-36 questionnaire scores cannot predict clinical remission, radiographic progression or the need for biological therapy in a three-year prospective study of a Brazilian early rheumatoid arthritis cohort. Rheumatol Int 32(12):3937–3943. doi:10.1007/s00296-011-2261-8 CrossRefPubMed da Mota LM, Dos Santos Neto LL, Oliveira AC, Pereira IA, Burlingame RW, Ménard HA (2012) Laurindo IM (2012) Baseline HAQ and SF-36 questionnaire scores cannot predict clinical remission, radiographic progression or the need for biological therapy in a three-year prospective study of a Brazilian early rheumatoid arthritis cohort. Rheumatol Int 32(12):3937–3943. doi:10.​1007/​s00296-011-2261-8 CrossRefPubMed
47.
go back to reference Mota LM, Santos Neto LL, Burlingame RW, Ménard HA, Pereira IA, Carvalho JF, Laurindo IM (2012) Disability and quality-of-life are not influenced by the prevalence of autoantibodies in early rheumatoid arthritis patients—results of the Brasília Cohort. Rev Bras Reumatol 52(6):824–829CrossRefPubMed Mota LM, Santos Neto LL, Burlingame RW, Ménard HA, Pereira IA, Carvalho JF, Laurindo IM (2012) Disability and quality-of-life are not influenced by the prevalence of autoantibodies in early rheumatoid arthritis patients—results of the Brasília Cohort. Rev Bras Reumatol 52(6):824–829CrossRefPubMed
48.
go back to reference Silva CR, Costa TF, de Oliveira TT, Muniz LF, da Mota LM (2013) Physical activity among patients from the Brasília cohort of early rheumatoid arthritis. Rev Bras Reumatol 53(5):394–399CrossRefPubMed Silva CR, Costa TF, de Oliveira TT, Muniz LF, da Mota LM (2013) Physical activity among patients from the Brasília cohort of early rheumatoid arthritis. Rev Bras Reumatol 53(5):394–399CrossRefPubMed
50.
go back to reference Prevoo ML, van’t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL (1995) Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 38:44–48CrossRefPubMed Prevoo ML, van’t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL (1995) Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 38:44–48CrossRefPubMed
51.
go back to reference Aletaha D, Nell VP, Stamm T, Uffmann M, Pflugbeil S, Machold K et al (2005) Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score. Arthritis Res Ther 7(4):R796–R806PubMedCentralCrossRefPubMed Aletaha D, Nell VP, Stamm T, Uffmann M, Pflugbeil S, Machold K et al (2005) Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score. Arthritis Res Ther 7(4):R796–R806PubMedCentralCrossRefPubMed
52.
go back to reference Sánchez T, Contreras-Yáñez I, Elías-López D, Aguilar Salinas CA, Pascual-Ramos V (2014) Prevalence of lipid phenotypes, serum lipid behaviour over follow-up and predictors of serum lipid levels in a cohort of Mexican Mestizo early rheumatoid arthritis patients treated with conventional disease-modifying anti-rheumatic drugs. Clin Exp Rheumatol 32(4):509–515PubMed Sánchez T, Contreras-Yáñez I, Elías-López D, Aguilar Salinas CA, Pascual-Ramos V (2014) Prevalence of lipid phenotypes, serum lipid behaviour over follow-up and predictors of serum lipid levels in a cohort of Mexican Mestizo early rheumatoid arthritis patients treated with conventional disease-modifying anti-rheumatic drugs. Clin Exp Rheumatol 32(4):509–515PubMed
Metadata
Title
Rheumatoid arthritis in Latin America: the importance of an early diagnosis
Authors
Licia Maria Henrique da Mota
Claiton Viegas Brenol
Penelope Palominos
Geraldo da Rocha Castelar Pinheiro
Publication date
01-03-2015
Publisher
Springer London
Published in
Clinical Rheumatology / Issue Special Issue 1/2015
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-015-3015-x

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