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Current Oral Health Reports

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01-12-2017 | Dental Stem Cells in Tissue Regeneration (F Setzer, Section Editor)

Revascularization of Immature Necrotic Teeth

Authors: Nikita B. Ruparel, Vanessa Chrepa, Jennifer L. Gibbs

Published in: Current Oral Health Reports | Issue 4/2017

Abstract

Purpose of Review

The objective of this review is to provide an overview of the past and present advancements in regenerative endodontics.

Recent Findings

Available literature clearly demonstrates high-clinical success of regenerative endodontic procedures (REP). Several recommendations made by the American Association of Endodontists (AAE) with regard to REP protocols are based on recent work demonstrating these as stem cell-based therapies. This review summarizes the role of stem cells and therefore the rationale for the currently recommended guidelines.

Summary

Clinical success of REP lies between 80 and 100% with root development observed in a significant number of treated cases. These procedures provide a unique advantage of continued root growth despite premature pulp necrosis in immature teeth. Research in the field of stem cell biology has greatly increased our understanding of tissue engineering in endodontics. Overall, REPs appear to be a viable treatment option for immature teeth with pulp necrosis.

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Title: Revascularization of Immature Necrotic Teeth
Authors: Nikita B. Ruparel
Vanessa Chrepa
Jennifer L. Gibbs
Publication date: 01-12-2017
Publisher: Springer International Publishing
Published in: Current Oral Health Reports / Issue 4/2017
Electronic ISSN: 2196-3002
DOI: https://doi.org/10.1007/s40496-017-0162-y

At a glance: The STEP trials

Springer Medicine

Revascularization of Immature Necrotic Teeth

Abstract

Purpose of Review

Recent Findings

Summary

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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