Retroperitoneal Mucinous Neoplasm Arising from Colonic Duplication Cyst

Excerpt

Enteric duplication cysts are uncommon abnormalities with a reported incidence of 1 in 4,500 to 10,000 live births. These lesions are defined as mucosa lined structures, contiguous and attached to the bowel wall, and surrounded by at least one smooth muscle layer. Most of them (80%) are diagnosed within the first 2 years of life and the symptoms depend on the location [1]. They can occur in any portion of the alimentary tract, but the retroperitoneum is a very unusual location; the most common location is the small bowel (duodenum 2–12% and jejuno-ileal > 50%), followed by the esophagus (15%), stomach (4–9%), and large bowel/rectum (7%). Complications can include hemorrhage, intussusception, obstruction, or malignant transformation [2]. Malignant change is an unusual complication of alimentary tract duplications and the exact incidence is unknown. Thirty-three cases of malignant tumors arising specifically from duplications of the large intestine have been reported including adenocarcinoma (n = 26), squamous cell carcinoma (n = 3), carcinoid tumor (n = 2), mucinous cystadenocarcinoma (n = 1), and gastrointestinal stromal tumor (n = 1) [3‐5]. The aim of this report is to describe the first case of a low-grade mucinous neoplasia that originated in a retroperitoneal colonic duplication cyst. …