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Published in: Pediatric Nephrology 6/2011

01-06-2011 | Original Article

Results of medical treatment and metabolic risk factors in children with urolithiasis

Authors: Metin Kaya Gürgöze, Mehmet Yusuf Sarı

Published in: Pediatric Nephrology | Issue 6/2011

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Abstract

Data on conservative treatment in children with urolithiasis are limited. The aim of the study was to determine the metabolic etiology and results of conservative treatment in children with urolithiasis. We evaluated the clinical presentation and metabolic features of 112 children with urolithiasis. The mean age at diagnosis of urolithiasis was 3.9 (range 0.1–18) years, and follow-up duration was 16.7 (range 1–36) months. The most common presenting symptoms were flank or abdominal pain and restlessness (25%). Urine analysis revealed metabolic abnormalities in 92% of cases, including hypocitraturia (42%), hyperoxaluria (32.1%), hypercalcuria (25%), hyperuricosuria (9.8%), and cystinuria (2.7%). Patients who had metabolic risk factors were treated according to underlying metabolic abnormalities. About half of these patients were stone free or stones were diminished in size. These results showed that early recognition and treatment of urinary metabolic abnormalities will reduce the number of invasive procedures and renal damage in children with urolithiasis.
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Metadata
Title
Results of medical treatment and metabolic risk factors in children with urolithiasis
Authors
Metin Kaya Gürgöze
Mehmet Yusuf Sarı
Publication date
01-06-2011
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Nephrology / Issue 6/2011
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-011-1803-3

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