Published in:
01-05-2007 | Letter
Response to comment on: Evans JMM, Ogston SA, Emslie-Smith A, Morris AD (2006) Risk of mortality and adverse cardiovascular outcomes in type 2 diabetes: a comparison of patients treated with sulphonylureas and metformin. Diabetologia 49:930–936
Authors:
J. M. M. Evans, A. D. Morris
Published in:
Diabetologia
|
Issue 5/2007
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Excerpt
To the Editor: In a recent letter to
Diabetologia [
1], D. Raccah questions the value of several recent observational studies, discussed by J. A. Tayek [
2], that have identified increased cardiovascular mortality among type 2 diabetic patients treated with sulphonylureas compared with patients prescribed other therapies (such as metformin). He argues that prospective, randomised clinical trials are necessary to establish whether sulphonylureas are linked with excess mortality. …