Top

European Archives of Oto-Rhino-Laryngology

Published in:

13-06-2023 | Respiratory Microbiota | Comment

The relationship between the upper aerodigestive microbiome axis and head and neck cancers: it is time to bet on it?

Authors: Pietro De Luca, Marco Radici, Angelo Camaioni

Published in: European Archives of Oto-Rhino-Laryngology | Issue 9/2023

Excerpt

One of the first scientists to explore the world of microbes and to unknowingly establish the basis of the microbiota’s world was Anthony van Leeuwenhoek, in 1681, who observed “more than 1000 living animalcules” while examining his own watery stools under the microscope; only a century and a half later, the debate around the existence of microorganisms in the human gut was started by the observation of a Scottish surgeon, John Goodsir, who discovered a microorganism which he named Sarcina ventriculi when examining the ejected fluid from the stomach of a 19-year old patient. …

Marchesi JR, Ravel J (2015) The vocabulary of microbiome research: a proposal. Microbiome 3:31CrossRefPubMedPubMedCentral

Irfan M, Delgado RZR, Frias-Lopez J (2020) The oral microbiome and cancer. Front Immunol 11:591088CrossRefPubMedPubMedCentral

Dhakal A, Upadhyay R, Wheeler C, Hoyd R, Karivedu V, Gamez ME, Valentin S, Vanputten M, Bhateja P, Bonomi M et al (2022) Association between tumor microbiome and hypoxia across anatomic subsites of head and neck cancers. Int J Mol Sci 23:15531. https://doi.org/10.3390/ijms232415531CrossRefPubMedPubMedCentral

Li Z, Fu R, Wen X, Wang Q, Huang X, Zhang L (2023) The significant clinical correlation of the intratumor oral microbiome in oral squamous cell carcinoma based on tissue-derived sequencing. Front Physiol 13:1089539. https://doi.org/10.3389/fphys.2022.1089539CrossRefPubMedPubMedCentral

Chan JYK, Cheung MK, Lan L, Ng C, Lau EHL, Yeung ZWC, Wong EWY, Leung L, Qu X, Cai L, Zhu H, Boon SS, Burk RD, Chan PKS, Chen Z (2022) Characterization of oral microbiota in HPV and non-HPV head and neck squamous cell carcinoma and its association with patient outcomes. Oral Oncol 135:106245. https://doi.org/10.1016/j.oraloncology.2022.106245CrossRefPubMed

Gong H, Shi Y, Zhou X et al (2014) Microbiota in the throat and risk factors for laryngeal carcinoma. Appl Environ Microbiol 80(23):7356–7363. https://doi.org/10.1128/AEM.02329-14CrossRefPubMedPubMedCentral

Title: The relationship between the upper aerodigestive microbiome axis and head and neck cancers: it is time to bet on it?
Authors: Pietro De Luca
Marco Radici
Angelo Camaioni
Publication date: 13-06-2023
Publisher: Springer Berlin Heidelberg
Keywords: Respiratory Microbiota
Human Papillomavirus
Streptococci
Laryngeal Cancer
Laryngeal Cancer
Campylobacter
Published in: European Archives of Oto-Rhino-Laryngology / Issue 9/2023
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-023-08037-2

2024 ASCO Annual Meeting

Springer Medicine

The relationship between the upper aerodigestive microbiome axis and head and neck cancers: it is time to bet on it?

Excerpt

2024 ASCO Annual Meeting

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 9/2023

Dysphagia outcomes in COVID-19 patients: experiences in long-term acute care hospital (LTACH)

The causal association between peripheral blood eosinophils and nasal polyps: a Mendelian randomization study

Unusual cause of unilateral facial oedema: intramuscular dirofilariasis

Normative data for certain vocal fold biomarkers among young normophonic adults using ultrasonography

Morphology-guided treatment of adult laryngeal and hypopharyngeal hemangioma: FD-EENT experience

Impact of social and economic factors on global thyroid cancer incidence and mortality