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Published in: Journal of Experimental & Clinical Cancer Research 1/2018

Open Access 01-12-2018 | Meeting Report

Reprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy

Authors: Maria Teresa Di Martino, Francesca Zazzeroni, Massimo Donadelli, Claudia Chiodoni, Michele Caraglia, Katia Scotlandi, Stefania Meschini, Carlo Leonetti

Published in: Journal of Experimental & Clinical Cancer Research | Issue 1/2018

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Excerpt

The 30thAnnual Conference of Italian Association of Cell Cultures (AICC) was held at Fondazione IRCCS Istituto Nazionale dei Tumori, in Milan, on November 27–28, 2017, with the Scientific Coordination of Claudia Chiodoni and Mario Paolo Colombo, from the same Institute. The conference was opened by Katia Scotlandi, President of the Italian Association of Cell Cultures. The main objective of the conference was to discuss the present knowledge on the role of immune cells in the tumor microenvironment, shaped by cells promoting tumor survival that could be reeducated to treat cancer. The meeting was organized in two days with 5 thematic sessions, an opening and a closing lecture, with national and international speakers. The organizers truly thank those who took part in the conference and made the Conference a success. …
Literature
2.
go back to reference Baer C, Squadrito ML, Laoui D, Thompson D, Hansen SK, Kiialainen A, et al. Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity. Nat Cell Biol. 2016; https://doi.org/10.1038/ncb337. Baer C, Squadrito ML, Laoui D, Thompson D, Hansen SK, Kiialainen A, et al. Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity. Nat Cell Biol. 2016; https://​doi.​org/​10.​1038/​ncb337.
4.
go back to reference Jeon JS, Bersini S, Gilardi M, Dubini G, Charest JL, Moretti M, et al. Human 3D vascularized organo typic microfluidic assays to study breast cancer cell extravasation. Proc Natl Acad Sci U S A. 2015;112:214–9.CrossRefPubMed Jeon JS, Bersini S, Gilardi M, Dubini G, Charest JL, Moretti M, et al. Human 3D vascularized organo typic microfluidic assays to study breast cancer cell extravasation. Proc Natl Acad Sci U S A. 2015;112:214–9.CrossRefPubMed
5.
go back to reference Warburg O. On respiratory impairment in cancer cells. Science. 1956;124:269–70. Warburg O. On respiratory impairment in cancer cells. Science. 1956;124:269–70.
7.
go back to reference Caffa I, D'Agostino V, Damonte P, Soncini D, Cea M, Monacelli F, et al. Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition. Oncotarget. 2015;6:11820–32.CrossRefPubMedPubMedCentral Caffa I, D'Agostino V, Damonte P, Soncini D, Cea M, Monacelli F, et al. Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition. Oncotarget. 2015;6:11820–32.CrossRefPubMedPubMedCentral
8.
11.
go back to reference Hess Michelini R, Freschi M, Manzo T, Jachetti E, Degl'Innocenti E, Grioni M, et al. Concomitant tumor and minor histocompatibility antigen-specific immunity initiaterejection and maintain remission from established spontaneous solid tumors. Cancer Res. 2010; https://doi.org/10.1158/0008-5472.CAN-09-4253. Hess Michelini R, Freschi M, Manzo T, Jachetti E, Degl'Innocenti E, Grioni M, et al. Concomitant tumor and minor histocompatibility antigen-specific immunity initiaterejection and maintain remission from established spontaneous solid tumors. Cancer Res. 2010; https://​doi.​org/​10.​1158/​0008-5472.​CAN-09-4253.
14.
go back to reference Camisaschi C, Vallacchi V, Vergani E, Tazzari M, Ferro S, Tuccitto A, et al. Targeting immune regulatory networks to counteract immune suppression in cancer. Vaccines (Basel). 2016;4(4):pii: E38.CrossRef Camisaschi C, Vallacchi V, Vergani E, Tazzari M, Ferro S, Tuccitto A, et al. Targeting immune regulatory networks to counteract immune suppression in cancer. Vaccines (Basel). 2016;4(4):pii: E38.CrossRef
17.
go back to reference Piconese S, Timperi E, Pacella I, Schinzari V, Tripodo C, Rossi M, et al. Human OX40 tunes the function of regulatory T cells in tumor and non tumor areas of hepatitis C virus-infected liver tissue. Hepatology. 2014; https://doi.org/10.1002/hep.27188. Piconese S, Timperi E, Pacella I, Schinzari V, Tripodo C, Rossi M, et al. Human OX40 tunes the function of regulatory T cells in tumor and non tumor areas of hepatitis C virus-infected liver tissue. Hepatology. 2014; https://​doi.​org/​10.​1002/​hep.​27188.
Metadata
Title
Reprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy
Authors
Maria Teresa Di Martino
Francesca Zazzeroni
Massimo Donadelli
Claudia Chiodoni
Michele Caraglia
Katia Scotlandi
Stefania Meschini
Carlo Leonetti
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Journal of Experimental & Clinical Cancer Research / Issue 1/2018
Electronic ISSN: 1756-9966
DOI
https://doi.org/10.1186/s13046-018-0710-x

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