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Malaria Journal
Published in: Malaria Journal 1/2015

Open Access 01-12-2015 | Case report

Repeated Plasmodium vivax malaria relapses in a Peruvian sailor

Authors: Adam P. McFarland, Juan F. Sanchez, Alejandro Mercado, Julio A. Ventocilla, Sofia Cavalcanti, Sofia Gonzalez, Andres G. Lescano

Published in: Malaria Journal | Issue 1/2015

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Abstract

Two Plasmodium vivax recurrences in a Peruvian sailor with weight above the 60 kg (cap for primaquine dosage) highlight the importance of adequate radical cure weight dosage for patient treatment and control efforts, particularly within the military.
Literature
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Ministerio de Salud del Peru. Norma Técnica de Salud para la atención de la Malaria y Malaria Grave en el Perú. Resolución Ministerial. 2007 No 076-2007/MINSA.
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Durand S, Cabezas C, Lescano A, Galvez M, Gutierrez S, Arrospide N, et al. Efficacy of three different regimens of primaquine for the prevention of relapses of Plasmodium vivax malaria in the Amazon Basin of Peru. Am J Trop Med Hyg. 2014;91:18–26.PubMedCentralCrossRefPubMed
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Santos JB, Luz FC, Deckers FA, Tauil PL. Subdoses of primaquine in overweight patients and malaria vivax relapses: report of two cases in the Federal District Brazil. Rev Soc Bras Med Trop. 2010;43:749–50.CrossRefPubMed
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Goller JL, Jolley D, Ringwald P, Biggs BA. Regional differences in the response of Plasmodium vivax malaria to primaquine as anti-relapse therapy. Am J Trop Med Hyg. 2007;76:203–7.PubMed
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Llanos-Cuentas A, Lacerda MN, Rueangweerayut R, Krudsood S, Gupta SK, Kochar SK, et al. Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study. Lancet. 2014;383:1049–58.CrossRefPubMed
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McCollum A, Soberon V, Salas C, Santolalla M, Udhayakumar V, Escalante A, et al. Genetic variation and recurrent parasitaemia in Peruvian Plasmodium vivax populations. Malar J. 2014;13:3–23.CrossRef
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Bright A, Alenazi T, Shokoples S, Tarning J, Paganotti GM, White NJ, et al. Genetic analysis of primaquine tolerance in a patient with relapsing vivax malaria. Emerg Infect Dis. 2013;19:802–5.PubMedCentralCrossRefPubMed
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Krotoski WA. The hypnozoite and malarial relapse. Prog Clin Parasitol. 1989;13:1–19.
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Pedro R, Guaraldo L, Campos D, Costa A, Daniel-Ribeiro C, Brasil P. Plasmodium vivax malaria relapses at a travel medicine centre in Rio de Janeiro, a non-endemic area in Brazil. Malar J. 2012;11:245–51.PubMedCentralCrossRefPubMed
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Metadata
Title
Repeated Plasmodium vivax malaria relapses in a Peruvian sailor
Authors
Adam P. McFarland
Juan F. Sanchez
Alejandro Mercado
Julio A. Ventocilla
Sofia Cavalcanti
Sofia Gonzalez
Andres G. Lescano
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2015
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-015-0959-x

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