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Clinical and Experimental Nephrology
Published in: Clinical and Experimental Nephrology 4/2008

01-08-2008 | Original Article

Renal pathology of ANCA-related vasculitis: proposal for standardization of pathological diagnosis in Japan

Authors: Kensuke Joh, Eri Muso, Hidekazu Shigematsu, Masato Nose, Michio Nagata, Yoshihiro Arimura, Wako Yumura, Takashi Wada, Kousaku Nitta, Hirofumi Makino, Yoshio Taguma, Hidetoshi Kaneoka, Yuhsuke Suzuki, Masaki Kobayashi, Akio Koyama, Joichi Usui, Hiroshi Hashimoto, Shoichi Ozaki, Yasuhiko Tomino, Kunihiro Yamagata

Published in: Clinical and Experimental Nephrology | Issue 4/2008

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Abstract

Background

In Japan, systematic evaluation of the histologic parameters of anti-neutrophil cytoplasmic autoantibodies (ANCA)-related vasculitis has been performed according to the Japanese classification by Shigematsu et al. However, this classification is quite different from that of the European Vasculitis Study Group (EUVAS) classification. Therefore, a histological common basis is needed to compare Japanese histological data with the international database.

Method

Histological parameters concerning glomerular, tubulointerstitial, and vascular lesions of ANCA-related vasculitis, which are indispensable for clinical management, were elucidated and defined by reviewing, utilizing the merits of, and amending the two scoring systems.

Results and conclusion

A new comprehensive and standardized scoring system, by which histological quantitative assessment can provide evidence for therapy planning, has been developed for renal biopsy of Japanese ANCA-related vasculitis.
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Metadata
Title
Renal pathology of ANCA-related vasculitis: proposal for standardization of pathological diagnosis in Japan
Authors
Kensuke Joh
Eri Muso
Hidekazu Shigematsu
Masato Nose
Michio Nagata
Yoshihiro Arimura
Wako Yumura
Takashi Wada
Kousaku Nitta
Hirofumi Makino
Yoshio Taguma
Hidetoshi Kaneoka
Yuhsuke Suzuki
Masaki Kobayashi
Akio Koyama
Joichi Usui
Hiroshi Hashimoto
Shoichi Ozaki
Yasuhiko Tomino
Kunihiro Yamagata
Publication date
01-08-2008
Publisher
Springer Japan
Published in
Clinical and Experimental Nephrology / Issue 4/2008
Print ISSN: 1342-1751
Electronic ISSN: 1437-7799
DOI
https://doi.org/10.1007/s10157-008-0052-7

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