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Journal of Cardiovascular Translational Research
Published in: Journal of Cardiovascular Translational Research 3/2014

01-04-2014

Renal Denervation: A Novel Non-pharmacological Approach in Heart Failure

Authors: Michael Böhm, Sebastian Ewen, Dominik Linz, Jan-C Reil, Stephan Schirmer, Christian Ukena, Felix Mahfoud

Published in: Journal of Cardiovascular Translational Research | Issue 3/2014

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Abstract

Heart failure is associated with activation of the sympathetic nervous system which presumably results in a progression of the syndrome and thereby in poor outcome. Renal denervation has shown to be effective in conditions with enhanced sympathetic activity like resistant hypertension and metabolic syndrome associated with sleep apnea. The first pilot trials assessing the effect of renal denervation on signs and symptoms of heart failure in patients with both preserved and reduced left ventricular ejection fraction are presently ongoing. The results of these studies will determine whether to proceed with larger prospective outcome trials. Altogether, renal denervation is a promising novel technique that may improve the outcome of patients with sympathetic hyperactivity and cardiovascular diseases.
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Metadata
Title
Renal Denervation: A Novel Non-pharmacological Approach in Heart Failure
Authors
Michael Böhm
Sebastian Ewen
Dominik Linz
Jan-C Reil
Stephan Schirmer
Christian Ukena
Felix Mahfoud
Publication date
01-04-2014
Publisher
Springer US
Published in
Journal of Cardiovascular Translational Research / Issue 3/2014
Print ISSN: 1937-5387
Electronic ISSN: 1937-5395
DOI
https://doi.org/10.1007/s12265-014-9549-5

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