Top

Published in:

01-04-2015 | Original Article

Relationship of high blood lactate levels with latency of visual-evoked potentials

Authors: Marinella Coco, Giovanna Alagona, Giulia De Maria, Giuseppe Rapisarda, Erminio Costanzo, Vincenzo Perciavalle, Valentina Perciavalle

Published in: Neurological Sciences | Issue 4/2015

Abstract

We studied, in healthy adult subjects, the association of high blood lactate levels, induced with an exhaustive exercise (12 subjects) or an intravenous infusion (four subjects) of a lactate solution (3 mg/kg in 1 min), with amplitude and latency of visual-evoked potentials. Amplitude of N75, P100, and N145 components did not show significant changes, whereas latency of P100 was reduced at exercise’s end and that of N145 increased 10 min after the conclusion. Therefore, an increase of blood lactate induced by an exhaustive exercise or an intravenous infusion appears to induce an improvement in the conduction time between eye and striate cortex, while it seems to evoke a worsening of intracortical communication between striate and extrastriate areas.

Meeusen R, Watson P, Hasegawa H, Roelands B, Piacentini MF (2007) Brain neurotransmitters in fatigue and overtraining. Appl Physiol Nutr Metab 32:857–864CrossRefPubMed

Bangsbo J (1998) Quantification of anaerobic energy production during intense exercise. Med Sci Sports Exerc 130:47–52CrossRef

Medbø JI, Tabata I (1993) Anaerobic energy release in working muscle during 30 s to 3 min of exhausting bicycling. J Appl Physiol 74:1654–1660

Dalsgaard MK, Quistorff B, Danielsen ER, Selmer C, Vogelsang T, Secher NH (2004) A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain. J Physiol 554:571–578PubMedCentralCrossRefPubMed

Rouach N, Koulakoff A, Abudara V, Willecke K, Giaume C (2008) Astroglial metabolic networks sustain hippocampal synaptic transmission. Science 322:1551–1555CrossRefPubMed

Coco M, Di Corrado D, Calogero RA, Perciavalle V, Maci T, Perciavalle V (2009) Attentional processes and blood lactate levels. Brain Res 1302:205–211CrossRefPubMed

Coco M, Alagona G, Rapisarda G, Costanzo E, Calogero RA, Va Perciavalle, Perciavalle V (2010) Elevated blood lactate is associated with increased motor cortex excitability. Somatosens Mot Res 27:1–8CrossRefPubMed

Coco M, Alagona G, Va Perciavalle, Cicirata V, Perciavalle V (2011) Spinal cord excitability is not influenced by elevated blood lactate levels. Somatosens Mot Res 28:19–24CrossRefPubMed

Coco M, Alagona G, Va Perciavalle, Rapisarda G, Costanzo E, Perciavalle V (2013) Brainstem excitability is not influenced by blood lactate levels. Somatosens Mot Res 30:90–95CrossRefPubMed

10.

Di Russo F, Pitzalis S, Spitoni G, Aprile T, Patria F, Spinelli D, Hillyard SA (2005) Identification of the neural sources of the pattern-reversal VEP. Neuroimage 24:874–886CrossRefPubMed

11.

Halliday AM (1993) Evoked Potentials in Clinical Testing. Churchill Livingstone, Edinburgh

12.

Ozkaya YG, Agar A, Haciuglu G, Yargicoglu P, Abidin I, Senturk UK (2003) Training induced alterations of visual evoked potentials are not related to body temperature. Int J Sports Med 24:359–362CrossRefPubMed

13.

Ozmerdivenli R, Bulut S, Bayar H, Karacabey K, Ciloglu F, Peker I, Tan U (2005) Effects of exercise on visual evoked potentials. Int J Neurosci 115:1043–1050CrossRefPubMed

14.

Zwierko T, Lubiński W, Lubkowska A, Niechwiej-Szwedo E, Czepita D (2011) The effect of progressively increased physical efforts on visual evoked potentials in volleyball players and non-athletes. J Sports Sci 29:1563–1572CrossRefPubMed

15.

Va Perciavalle, Alagona G, Maci T, Petralia MC, Perciavalle V, Coco M (2014) Attentional processes during submaximal exercises. Somatosens Mot Res 31:1–6CrossRef

16.

Buckley JD, Bourdon PC, Woolford SM (2003) Effect of measuring blood lactate concentrations using different automated lactate analysers on blood lactate transition thresholds. J Sci Med Sport 6:408–421CrossRefPubMed

17.

Kristensen GB, Christensen NG, Thue G, Sandberg S (2005) Between-lot variation in external quality assessment of glucose: clinical importance and effect on participant performance evaluation. Clin Chem 51:1626–1632CrossRef

18.

Green JM, McLester JR, Crews TR, Wickwire PJ, Pritchett RC, Redden A (2005) RPE-lactate dissociation during extended cycling. Eur J Appl Physiol 94:145–150CrossRefPubMed

19.

Jasper HH (1958) The ten–twenty electrode system of the International Federation. Electroencephalogr Clin Neurophysiol 10:371–375

20.

Müller M, Schimrigk K (1994) A comparative assessment of cerebral haemodynamics in the basilar artery and carotid territory by transcranial Doppler sonography in normal subjects. Ultrasound Med Biol 20:677–687CrossRefPubMed

21.

Sjodin B, Jacobs I (1981) Onset of blood lactate accumulation and marathon running performance. Int J Sports Med 2:23–26CrossRefPubMed

22.

Gleeson M (2007) Immune function in sport and exercise. J Appl Physiol 103:693–699CrossRefPubMed

23.

Delp MD, Armstrong RB, Godfrey DA, Laughlin MH, Ross CD, Wilkerson MK (2001) Exercise increases blood flow to locomotor, vestibular, cardiorespiratory and visual regions of the brain in miniature swine. J Physiol 533:849–859PubMedCentralCrossRefPubMed

24.

Posner MI, Petersen SE (1990) The attention system of the human brain. Ann Rev Neurosci 13:25–42CrossRefPubMed

25.

Coco M, Caggia S, Musumeci G, Perciavalle V, Graziano AC, Pannuzzo G, Cardile V (2013) Sodium L-lactate differently affects brain-derived neurothrophic factor, inducible nitric oxide synthase, and heat shock protein 70 kDa production in human astrocytes and SH-SY5Y cultures. J Neurosci Res 91:313–320CrossRefPubMed

Title: Relationship of high blood lactate levels with latency of visual-evoked potentials
Authors: Marinella Coco
Giovanna Alagona
Giulia De Maria
Giuseppe Rapisarda
Erminio Costanzo
Vincenzo Perciavalle
Valentina Perciavalle
Publication date: 01-04-2015
Publisher: Springer Milan
Published in: Neurological Sciences / Issue 4/2015
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-014-2015-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Relationship of high blood lactate levels with latency of visual-evoked potentials

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 4/2015

Protective effects of Vitamin C against spinal cord injury-induced renal damage through suppression of NF-κB and proinflammatory cytokines

The distinctive contrast of multiple sclerosis epidemiology between Persians and Armenian minority community of Isfahan city, Iran

Postencephalitic parkinsonism and selective involvement of substantia nigra

RETRACTED ARTICLE: Association of Catechol-O-methyltransferase val/met polymorphism with cognitive function in Gilles de la Tourette syndrome patients

Neurogenic pulmonary edema caused by bilateral medial medullary infarction

Pitfall in neurology: giant cell arteritis mimicking ocular myasthenia gravis