Published in:
01-08-2019 | Editorial
Refining risk in diabetes and CAD with SPECT MPI: New insights and future challenges
Authors:
Syed Y. Naqvi, MD, Steven D. Wittlin, MD, Ronald G. Schwartz, MD, MS
Published in:
Journal of Nuclear Cardiology
|
Issue 4/2019
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Excerpt
Diabetes mellitus (DM) is an expanding global epidemic. Estimates of a global prevalence of 415 million people and total health expenditure of 673 billion US dollars have been reported.
1 The prevalence of individuals between 20 and 79 years with diabetes is predicted to rise to 642 million by 2040.
1 Assessment of morbid risk of diabetes is of substantial importance in the allocation of resources to address the human and financial burdens of this growing global health threat. Epidemiological studies have demonstrated that diabetes places patients at an elevated risk for developing coronary artery disease (CAD).
2,
3 A large meta-analysis of 102 studies confirmed a two-fold excess risk for vascular disease in DM.
4 Since the landmark study by Haffner first reported the equivalence of risk of diabetes and CAD,
5 widespread controversy has ensued with several studies, which have supported
6-
10 or challenged
11-
17 the concept of risk equivalent of DM and CAD. …
