01-03-2015 | Vascular-Interventional
Reduction of CT beam hardening artefacts of ethylene vinyl alcohol copolymer by variation of the tantalum content: evaluation in a standardized aortic endoleak phantom
Published in: European Radiology | Issue 3/2015
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Objectives
Our aim was to develop an aortic stent graft phantom to simulate endoleak treatment and to find a tantalum content (TC) of ethylene-vinyl-alcohol-copolymer that causes fewer computed tomography (CT) beam hardening artefacts, but still allows for fluoroscopic visualization.
Methods
Ethylene-vinyl-alcohol-copolymer specimens of different TC (10–50 %, and 100 %) were injected in an aortic phantom bearing a stent graft and endoleak cavities with simulated re-perfusion. Fluoroscopic visibility of the ethylene-vinyl-alcohol-copolymer specimens was analyzed. In addition, six radiologists analyzed endoleak visibility, and artefact intensity of ethylene-vinyl-alcohol-copolymer in CT.
Results
Reduction of TC significantly decreased CT artefact intensity of ethylene-vinyl-alcohol-copolymer and increased visibility of endoleak re-perfusion (p < 0.000). It also significantly decreased fluoroscopic visibility of ethylene-vinyl-alcohol-copolymer (R = 0.883, p ≤ 0.01), and increased the active embolic volumes prior to visualization (Δ ≥ 40 μl). Ethylene-vinyl-alcohol-copolymer specimens with a TC of 45–50 % exhibited reasonable visibility, a low active embolic volume and a tolerable CT artefact intensity.
Conclusions
The developed aortic stent graft phantom allows for a reproducible simulation of embolization of endoleaks. The data suggest a reduction of the TC of ethylene-vinyl-alcohol-copolymer to 45 –50 % of the original, to interfere less with diagnostic imaging in follow-up CT examinations, while still allowing for fluoroscopic visualization.
Key Points
• Standard Tantalum-ethylene-vinyl-alcohol-copolymer causes severe beam hardening artefacts, limiting cross-sectional imaging.
• Increased peripheral use of Tantalum-ethylene-vinyl-alcohol-copolymer requires a formulation causing fewer artefacts.
• Treatment of endoleaks can be simulated with an aortic stent graft phantom.
• Tantalum contents of 45–50 % exhibit sufficient visualization and tolerable low artefacts.