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01-11-2016 | Original Article

Rectal misoprostol plus perivascular vasopressin versus tourniquet to decrease blood loss during abdominal myomectomy

Authors: Ibrahim Abd Elgafor El Sharkwy, Mohamed Lotfy, Hussein Mohamed Abdeldayem, Ali Abdel Hameed

Published in: Gynecological Surgery | Issue 4/2016

Abstract

The aim of this study is to compare between combined preoperative rectal misoprostol plus perivascular vasopressin and tourniquet to decrease blood loss during abdominal myomectomy. In this randomized study, 104 patients were randomly allocated to receive either combined 400 μg rectal misoprostol plus perivascular vasopressin (n = 52) or tourniquet (n = 52). The main outcome measure was the operative blood loss. Secondary outcome measures included the requirement for blood transfusion, the change in hemoglobin level after operation, and incidence of complications. Blood loss was significantly greater in the group with tourniquet (375.7 ± 292.3 mL) than in the group with rectal misoprostol plus perivascular vasopressin (254.1 ± 185.4 mL) (P = 0.03). The group with tourniquet had a significant decrease in Hb level 24 h after operation (P < 0.04). Blood transfusion rate was significantly greater in the group with tourniquet (P < 0.04). The febrile morbidity was comparable in the two groups. Rectal misoprostol plus perivascular vasopressin was found to be more effective than tourniquet for decreasing blood loss during abdominal myomectomy.

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Title: Rectal misoprostol plus perivascular vasopressin versus tourniquet to decrease blood loss during abdominal myomectomy
Authors: Ibrahim Abd Elgafor El Sharkwy
Mohamed Lotfy
Hussein Mohamed Abdeldayem
Ali Abdel Hameed
Publication date: 01-11-2016
Publisher: Springer Berlin Heidelberg
Published in: Gynecological Surgery / Issue 4/2016
Print ISSN: 1613-2076
Electronic ISSN: 1613-2084
DOI: https://doi.org/10.1007/s10397-016-0956-2

At a glance: The STEP trials

Springer Medicine

Rectal misoprostol plus perivascular vasopressin versus tourniquet to decrease blood loss during abdominal myomectomy

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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