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Journal of Nuclear Cardiology
Published in: Journal of Nuclear Cardiology 1/2018

01-02-2018 | Review Article

Reasons and implications of agreements and disagreements between coronary flow reserve, fractional flow reserve, and myocardial perfusion imaging

Authors: Manish Motwani, PhD, Mahsaw Motlagh, BA, Anuj Gupta, MD, Daniel S. Berman, MD, Piotr J. Slomka, PhD

Published in: Journal of Nuclear Cardiology | Issue 1/2018

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Abstract

Information on coronary physiology and myocardial blood flow (MBF) in patients with suspected angina is increasingly important to inform treatment decisions. A number of different techniques including myocardial perfusion imaging (MPI), noninvasive estimation of MBF, and coronary flow reserve (CFR), as well as invasive methods for CFR and fractional flow reserve (FFR) are now readily available. However, despite their incorporation into contemporary guidelines, these techniques are still poorly understood and their interpretation to guide revascularization decisions is often inconsistent. In particular, these inconsistencies arise when there are discrepancies between the various techniques. The purpose of this article is therefore to review the basic principles, techniques, and clinical value of MPI, FFR, and CFR—with particular focus on interpreting their agreements and disagreements.
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Metadata
Title
Reasons and implications of agreements and disagreements between coronary flow reserve, fractional flow reserve, and myocardial perfusion imaging
Authors
Manish Motwani, PhD
Mahsaw Motlagh, BA
Anuj Gupta, MD
Daniel S. Berman, MD
Piotr J. Slomka, PhD
Publication date
01-02-2018
Publisher
Springer US
Published in
Journal of Nuclear Cardiology / Issue 1/2018
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-015-0375-1

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