Raloxifene hydrochloride is a selective estrogen receptor (ER) modulator which is used in the treatment of osteoporosis. Due to its relationship with tamoxifen and the results of previous studies, it has been hypothesised that raloxifene might prevent breast cancer. Larger scale randomised evidence regarding the effect of raloxifene on adverse outcomes such as venous thromboembolism and endometrial hyperplasia/carcinoma is also important in guiding clinical use. …
Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.