Top

Journal of Radiation Oncology

Published in:

01-06-2020 | Radiotherapy | Original Research

Radiotherapy for maxillary sinus carcinoma: dosimetric comparison of volumetric modulated arc therapy with 0° and 90° collimator intensity modulated radiation therapy

Authors: Yong Sang, Guoping Shan, Kainan Shao, Fujun Hu, Jing Chen

Published in: Journal of Radiation Oncology | Issue 1-2/2020

Abstract

Object

To compare volumetric modulated arc therapy (VMAT) with 0° and 90° collimator intensity modulated radiation therapy (IMRT) plans for treatment of maxillary sinus carcinomas (MSCs).

Methods

Eighteen MSC were re-planned for VMAT (two full arcs), 0° collimator 9 beams IMRT (zc-IMRT) and 2 beams with 90° collimator and the remaining 7 beams with 0° collimator IMRT (nc-IMRT). The conformity and homogeneity index (CI and HI) of target volume, dose-volume histogram (DVH) of organs at risk (OARs), and monitor units (MUs) were analyzed.

Results

The CI of VMAT with GTV, PTV,1 and PTV2 found significantly more than zc-IMRT and nc-IMRT. The HI of nc-IMRT found significantly smaller than VMAT. In terms of OARs, VMAT significantly reduced the maximum point dose of optic chiasm, the ipsilateral lens, MUs, and the D_1% of the ipsilateral lens compared with IMRT. VMAT significantly reduced the maximum point dose of ipsilateral optic nerve, the D_1% of optic chiasm, the ipsilateral optic nerve and the mean dose of contralateral eyeball compared with zc-IMRT. For the two IMRT group plans, comparison with zc-IMRT, nc-IMRT could significantly reduce the maximum point dose of ipsilateral lens, the D_1% of ipsilateral lens and the MUs.

Conclusions

The VMAT has better CI of target volume and could have better OARs sparing effects for optic chiasm, ipsilateral lens and ipsilateral optic nerve compared with IMRT for MSCs. The VMAT also could use fewer MUs and has lower treatment delivery times. The nc-IMRT could have better ipsilateral lens sparing and use fewer MUs compared with zc-IMRT. Therefore we could protect the ipsilateral lens better through changing the angle of the collimator from 0° to 90° when the IMRT technique is used for the treatment of MSCs.

Martínez-Rodríguez N, Dorado CB, Brinkmann JCB et al (2018) Dental considerations in diagnosis of maxillary sinus carcinoma: a patient series of 24 cases. J Am Dent Assoc 149:976–982CrossRef

Dubal PM, Bhojwani A, Patel TD, Zuckerman O, Baredes S, Liu JK, Eloy JA (2016) Squamous cell carcinoma of the maxillary sinus: a population-based analysis. Laryngoscope 126:399–404CrossRef

Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Furusawa J, Yoshida D, Fujima N, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S (2014) The incidence of late neck recurrence in N0 maxillary sinus squamous cell carcinomas after superselective intra-arterial chemoradiotherapy without prophylactic neck irradiation. Eur Arch Oto-Rhino-L 271:2767–2770CrossRef

Jiang GL, Ang KK, Peters LJ, Wendt CD, Oswald MJ, Goepfert H (1991) Maxillary sinus carcinomas: natural history and results of postoperative radiotherapy. Radiother Oncol 21:193–200CrossRef

Kim S, Lee IJ, Kim YB, Koom WS, Jeon BC, Lee CG, Kim GE, Keum KC (2009) A comparison of treatment plans using linac-based intensity-modulated radiation therapy and helical tomotherapy for maxillary sinus carcinoma. Technol Cancer Res Treat 8:257–263CrossRef

Orlandi E, Giandini T, Iannacone E, de Ponti E, Carrara M, Mongioj V, Stucchi C, Tana S, Bossi P, Licitra L, Fallai C, Pignoli E (2014) Radiotherapy for unresectable sinonasal cancers: Dosimetric comparison of intensity modulated radiation therapy with coplanar and non-coplanar volumetric modulated arc therapy. Radiother Oncol 113:260–266CrossRef

Chera BS, Malyapa R, Louis D, Mendenhall WM, Li Z, Lanza DC, Yeung D, Mendenhall NP (2009) Proton therapy for maxillary sinus carcinoma. Am J Clin Oncol-Canc 32:296–303CrossRef

Mock U, Georg D, Bogner J, Auberger T, Pötter R (2004) Treatment planning comparison of conventional, 3D conformal, and intensity-modulated photon (IMRT) and proton therapy for paranasal sinus carcinoma. Int J Radiat Oncol Biol Phys 58:147–154CrossRef

Lomax AJ, Goitein M, Adams J (2003) Intensity modulation in radiotherapy: photons versus protons in the paranasal sinus. Radiother Oncol 66:11–18CrossRef

10.

Lu JY, Zheng J, Zhang WZ et al (2016) Flattening Filter-Free Beams in Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy for Sinonasal Cancer. PLoS One 11:e0146604CrossRef

11.

Gupta S, Laviraj MA, Haresh KP, Sharma DN, Pandey D, Prabhakar R, Rajendran M, Julka PK, Rath GK (2014) A Dosimetric comparison of VMAT and IMRT in Sinonasal cancers. Int J Radiat Oncol Biol Phys 88:493CrossRef

12.

Jeong Y, Lee S, Kwak J, Cho I, Yoon S, Kim J, Park J, Choi E, Song S, Kim Y, Kim S, Joo J, Ahn S (2014) A Dosimetric comparison of volumetric modulated arc therapy (VMAT) and non-coplanar intensity modulated radiation therapy (IMRT) for nasal cavity and paranasal sinus cancer. Int J Radiat Oncol Biol Phys 90:S865CrossRef

13.

Narita Y, Kato T, Ono T et al (2018) Effect of anatomical change on dose distribution during radiotherapy for maxillary sinus carcinoma: passive scattering proton therapy versus volumetric-modulated arc therapy. Brit J Radiol 20180273

14.

Huang D, Xia P, Akazawa P, Akazawa C, Quivey JM, Verhey LJ, Kaplan M, Lee N (2003) Comparison of treatment plans using intensity-modulated radiotherapy and three-dimensional conformal radiotherapy for paranasal sinus carcinoma. Int J Radiat Oncol Biol Phys 56:158–168CrossRef

15.

Lu SH, Cheng JCH, Kuo SH et al (2012) Volumetric modulated arc therapy for nasopharyngeal carcinoma: a dosimetric comparison with TomoTherapy and step-and-shoot IMRT. Radiother Oncol 3:324–330CrossRef

16.

Lee FKH, Yip CWY, Cheung FCH, Leung AKC, Chau RMC, Ngan RKC (2014) Dosimetric difference amongst 3 techniques: TomoTherapy, sliding-window intensity-modulated radiotherapy (IMRT), and RapidArc radiotherapy in the treatment of late-stage nasopharyngeal carcinoma (NPC). Med Dosim 39:44–49CrossRef

17.

Wang J, Chen Z, Li W, Qian W, Wang X, Hu W (2018) A new strategy for volumetric-modulated arc therapy planning using autoplanning based multicriteria optimization for nasopharyngeal carcinoma. Radiat Oncol 13:94–104CrossRef

18.

Weiss E, Siebers JV, Keall PJ (2007) An analysis of 6-MV versus 18-MV photon energy plans for intensity-modulated radiation therapy (IMRT) of lung cancer. Radiother Oncol 82:55–62CrossRef

19.

Bristol IJ, Ahamad A, Garden AS, Morrison WH, Hanna EY, Papadimitrakopoulou VA, Rosenthal DI, Ang KK (2007) Postoperative radiotherapy for maxillary sinus cancer: long-term outcomes and toxicities of treatment. Int J Radiat Oncol Biol Phys 68:719–730CrossRef

20.

Hoppe BS, Stegman LD, Zelefsky MJ, Rosenzweig KE, Wolden SL, Patel SG, Shah JP, Kraus DH, Lee NY (2007) Treatment of nasal cavity and paranasal sinus cancer with modern radiotherapy techniques in the postoperative setting-the MSKCC experience. Int J Radiat Oncol Biol Phys 67:691–702CrossRef

21.

Dulguerov P, Jacobsen MS, Allal AS, Lehmann W, Calcaterra T (2001) Nasal and paranasal sinus carcinoma: are we making progress? A series of 220 patients and a systematic review. Cancer 92:3012–3029CrossRef

22.

Kreppel M, Safi AF, Scheer M, Nickenig HJ, Zöller J, Preuss S, Meyer M, Rothamel D, Dreiseidler T (2016) The importance of early diagnosis in patients with maxillary sinus carcinoma. Eur Arch Oto-Rhino-L 273:2629–2635CrossRef

23.

Ono T, Tanaka N, Umeno H, Chitose SI, Shin B, Aso T, On K, Hattori C, Etoh H, Kakuma T, Abe T (2017) Treatment outcomes of locally advanced squamous cell carcinoma of the maxillary sinus treated with chemoradioselection using superselective intra-arterial cisplatin and concomitant radiation: implications for prognostic factors. J Cranio-Maxillofac Surg 45:2128–2134CrossRef

24.

Nishio N, Fujimoto Y, Hiramatsu M, Maruo T, Tsuzuki H, Mukoyama N, Shimono M, Sone M, Kawabe Y, Saito K, Fujii M, Nakashima T (2018) Maxillary sinus carcinoma outcomes over 60 years: experience at a single institution. Nagoya J Med Sci 80:91–98

25.

Nishio N, Fujimoto Y, Fujii M, Saito K, Hiramatsu M, Maruo T, Iwami K, Kamei Y, Yagi S, Takahashi M, Hayashi Y, Ando A, Nakashima T (2015) Craniofacial resection for T4 maxillary sinus carcinoma: managing cases with involvement of the Skull Base. Otolaryng Head Neck 153:231–238CrossRef

26.

Kondo A, Kurose M, Obata K et al (2016) A clinical study of maxillary sinus squamous cell carcinoma. Adv Otorhinolaryngol 77:83–87

27.

Mancosu P, Cozzi L, Fogliata A, Lattuada P, Reggiori G, Cantone MC, Navarria P, Scorsetti M (2010) Collimator angle influence on dose distribution optimization for vertebral metastases using volumetric modulated arc therapy. Med Phys 37:4133–4137CrossRef

28.

Tas B, Bilge H, Ozturk ST (2016) An investigation of the dose distribution effect related with collimator angle in volumetric arc therapy of prostate cancer. J Med Phys 41:100–105CrossRef

Title: Radiotherapy for maxillary sinus carcinoma: dosimetric comparison of volumetric modulated arc therapy with 0° and 90° collimator intensity modulated radiation therapy
Authors: Yong Sang
Guoping Shan
Kainan Shao
Fujun Hu
Jing Chen
Publication date: 01-06-2020
Publisher: Springer Berlin Heidelberg
Keyword: Radiotherapy
Published in: Journal of Radiation Oncology / Issue 1-2/2020
Print ISSN: 1948-7894
Electronic ISSN: 1948-7908
DOI: https://doi.org/10.1007/s13566-020-00422-2

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Watch now

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras

Prof. Fabrice Barlesi

Developed by: Springer Medicine

At a glance: The STEP trials

Springer Medicine

Abstract

Object

Methods

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 1-2/2020

Comparison of ICRU 38 rectal reference point dose estimates with measured dose in vivo in cobalt-60 HDR brachytherapy for cervical cancer

Capturing 3D patient features for rapid prototyping in radiotherapy prior to simulation

A single-institution study of intraoperative radiation therapy (IORT) using electronic brachytherapy

Perioperative high-dose-rate brachytherapy (PoHDR) in the multidisciplinary management of adult soft tissue sarcomas: a realistic alternative for a moderate radiotherapy dose escalation

Biologic subtypes as a predictor of local control in patients with brain metastases from breast cancer after stereotactic radiosurgery

Radiofrequency radiation: carcinogenic and other potential risks

Keynote webinar | Spotlight on antibody–drug conjugates in cancer