Skip to main content
Top
Published in: European Radiology 1/2018

Open Access 01-01-2018 | Computed Tomography

Radiation dose reduction for CT assessment of urolithiasis using iterative reconstruction: A prospective intra-individual study

Authors: Annemarie M. den Harder, Martin J. Willemink, Pieter J. van Doormaal, Frank J. Wessels, M. T. W. T. Lock, Arnold M. R. Schilham, Ricardo P. J. Budde, Tim Leiner, Pim A. de Jong

Published in: European Radiology | Issue 1/2018

Login to get access

Abstract

Objective

To assess the performance of hybrid (HIR) and model-based iterative reconstruction (MIR) in patients with urolithiasis at reduced-dose computed tomography (CT).

Methods

Twenty patients scheduled for unenhanced abdominal CT for follow-up of urolithiasis were prospectively included. Routine dose acquisition was followed by three low-dose acquisitions at 40%, 60% and 80% reduced doses. All images were reconstructed with filtered back projection (FBP), HIR and MIR. Urolithiasis detection rates, gall bladder, appendix and rectosigmoid evaluation and overall subjective image quality were evaluated by two observers.

Results

74 stones were present in 17 patients. Half the stones were not detected on FBP at the lowest dose level, but this improved with MIR to a sensitivity of 100%. HIR resulted in a slight decrease in sensitivity at the lowest dose to 72%, but outperformed FBP. Evaluation of other structures with HIR at 40% and with MIR at 60% dose reductions was comparable to FBP at routine dose, but 80% dose reduction resulted in non-evaluable images.

Conclusions

CT radiation dose for urolithiasis detection can be safely reduced by 40 (HIR)–60 (MIR) % without affecting assessment of urolithiasis, possible extra-urinary tract pathology or overall image quality.

Key Points

• Iterative reconstruction can be used to substantially lower the radiation dose.
• This allows for radiation reduction without affecting sensitivity of stone detection.
• Possible extra-urinary tract pathology evaluation is feasible at 40–60% reduced dose.
Appendix
Available only for authorised users
Literature
1.
go back to reference Heidenreich A, Desgrandschamps F, Terrier F (2002) Modern approach of diagnosis and management of acute flank pain: Review of all imaging modalities. Eur Urol 41:351–362CrossRefPubMed Heidenreich A, Desgrandschamps F, Terrier F (2002) Modern approach of diagnosis and management of acute flank pain: Review of all imaging modalities. Eur Urol 41:351–362CrossRefPubMed
2.
go back to reference Bartoletti R, Cai T, Mondaini N et al (2007) Epidemiology and risk factors in urolithiasis. Urol Int 79(Suppl 1):3–7 Bartoletti R, Cai T, Mondaini N et al (2007) Epidemiology and risk factors in urolithiasis. Urol Int 79(Suppl 1):3–7
4.
go back to reference Turk C, Petrik A, Sarica K et al (2016) EAU guidelines on diagnosis and conservative management of urolithiasis. Eur Urol 69:468–474CrossRefPubMed Turk C, Petrik A, Sarica K et al (2016) EAU guidelines on diagnosis and conservative management of urolithiasis. Eur Urol 69:468–474CrossRefPubMed
5.
go back to reference Coursey CA, Casalino DD, Remer EM et al (2012) ACR appropriateness criteria(R) acute onset flank pain--suspicion of stone disease. Ultrasound Q 28:227–233CrossRefPubMed Coursey CA, Casalino DD, Remer EM et al (2012) ACR appropriateness criteria(R) acute onset flank pain--suspicion of stone disease. Ultrasound Q 28:227–233CrossRefPubMed
6.
go back to reference Pearle MS, Goldfarb DS, Assimos DG et al (2014) Medical management of kidney stones: AUA guideline. J Urol 192:316–324CrossRefPubMed Pearle MS, Goldfarb DS, Assimos DG et al (2014) Medical management of kidney stones: AUA guideline. J Urol 192:316–324CrossRefPubMed
7.
go back to reference Veldhoen S, Laqmani A, Derlin T et al (2014) 256-MDCT for evaluation of urolithiasis: Iterative reconstruction allows for a significant reduction of the applied radiation dose while maintaining high subjective and objective image quality. J Med Imaging Radiat Oncol. doi:10.1111/1754-9485.12159 PubMed Veldhoen S, Laqmani A, Derlin T et al (2014) 256-MDCT for evaluation of urolithiasis: Iterative reconstruction allows for a significant reduction of the applied radiation dose while maintaining high subjective and objective image quality. J Med Imaging Radiat Oncol. doi:10.​1111/​1754-9485.​12159 PubMed
8.
go back to reference Moore CL, Daniels B, Ghita M et al (2015) Accuracy of reduced-dose computed tomography for ureteral stones in emergency department patients. Ann Emerg Med 65:189–198CrossRefPubMed Moore CL, Daniels B, Ghita M et al (2015) Accuracy of reduced-dose computed tomography for ureteral stones in emergency department patients. Ann Emerg Med 65:189–198CrossRefPubMed
9.
go back to reference Fontarensky M, Alfidja A, Perignon R et al (2015) Reduced radiation dose with model-based iterative reconstruction versus standard dose with adaptive statistical iterative reconstruction in abdominal CT for diagnosis of acute renal colic. Radiology 276:156–166CrossRefPubMed Fontarensky M, Alfidja A, Perignon R et al (2015) Reduced radiation dose with model-based iterative reconstruction versus standard dose with adaptive statistical iterative reconstruction in abdominal CT for diagnosis of acute renal colic. Radiology 276:156–166CrossRefPubMed
10.
go back to reference Glazer DI, Maturen KE, Cohan RH et al (2014) Assessment of 1 mSv urinary tract stone CT with model-based iterative reconstruction. AJR Am J Roentgenol 203:1230–1235CrossRefPubMed Glazer DI, Maturen KE, Cohan RH et al (2014) Assessment of 1 mSv urinary tract stone CT with model-based iterative reconstruction. AJR Am J Roentgenol 203:1230–1235CrossRefPubMed
11.
go back to reference Khawaja RD, Singh S, Blake M et al (2015) Ultra-low dose abdominal MDCT: Using a knowledge-based iterative model reconstruction technique for substantial dose reduction in a prospective clinical study. Eur J Radiol 84:2–10CrossRefPubMed Khawaja RD, Singh S, Blake M et al (2015) Ultra-low dose abdominal MDCT: Using a knowledge-based iterative model reconstruction technique for substantial dose reduction in a prospective clinical study. Eur J Radiol 84:2–10CrossRefPubMed
12.
go back to reference Deak PD, Smal Y, Kalender WA (2010) Multisection CT protocols: Sex- and age-specific conversion factors used to determine effective dose from dose-length product. Radiology 257:158–166CrossRefPubMed Deak PD, Smal Y, Kalender WA (2010) Multisection CT protocols: Sex- and age-specific conversion factors used to determine effective dose from dose-length product. Radiology 257:158–166CrossRefPubMed
13.
go back to reference de Merigot Treigny O, Bou Nasr E, Almont T et al (2015) The cumulated stone diameter: A limited tool for stone burden estimation. Urology 86:477–481CrossRef de Merigot Treigny O, Bou Nasr E, Almont T et al (2015) The cumulated stone diameter: A limited tool for stone burden estimation. Urology 86:477–481CrossRef
14.
go back to reference Gervaise A, Gervaise-Henry C, Pernin M, Naulet P, Junca-Laplace C, Lapierre-Combes M (2016) How to perform low-dose computed tomography for renal colic in clinical practice. Diagn Interv Imaging 97:393–400CrossRefPubMed Gervaise A, Gervaise-Henry C, Pernin M, Naulet P, Junca-Laplace C, Lapierre-Combes M (2016) How to perform low-dose computed tomography for renal colic in clinical practice. Diagn Interv Imaging 97:393–400CrossRefPubMed
15.
go back to reference Lukasiewicz A, Bhargavan-Chatfield M, Coombs L et al (2014) Radiation dose index of renal colic protocol CT studies in the united states: A report from the american college of radiology national radiology data registry. Radiology 271:445–451CrossRefPubMedPubMedCentral Lukasiewicz A, Bhargavan-Chatfield M, Coombs L et al (2014) Radiation dose index of renal colic protocol CT studies in the united states: A report from the american college of radiology national radiology data registry. Radiology 271:445–451CrossRefPubMedPubMedCentral
16.
go back to reference Niemann T, Kollmann T, Bongartz G (2008) Diagnostic performance of low-dose CT for the detection of urolithiasis: A meta-analysis. AJR Am J Roentgenol 191:396–401CrossRefPubMed Niemann T, Kollmann T, Bongartz G (2008) Diagnostic performance of low-dose CT for the detection of urolithiasis: A meta-analysis. AJR Am J Roentgenol 191:396–401CrossRefPubMed
17.
go back to reference McLaughlin PD, Murphy KP, Hayes SA et al (2014) Non-contrast CT at comparable dose to an abdominal radiograph in patients with acute renal colic; impact of iterative reconstruction on image quality and diagnostic performance. Insights Imaging 5:217–230CrossRefPubMedPubMedCentral McLaughlin PD, Murphy KP, Hayes SA et al (2014) Non-contrast CT at comparable dose to an abdominal radiograph in patients with acute renal colic; impact of iterative reconstruction on image quality and diagnostic performance. Insights Imaging 5:217–230CrossRefPubMedPubMedCentral
18.
go back to reference den Harder AM, Willemink MJ, Budde RP, Schilham AM, Leiner T, de Jong PA (2015) Hybrid and model-based iterative reconstruction techniques for pediatric CT. AJR Am J Roentgenol 204:645–653CrossRef den Harder AM, Willemink MJ, Budde RP, Schilham AM, Leiner T, de Jong PA (2015) Hybrid and model-based iterative reconstruction techniques for pediatric CT. AJR Am J Roentgenol 204:645–653CrossRef
19.
go back to reference Willemink MJ, Schilham AM, Leiner T, Mali WP, de Jong PA, Budde RP (2013) Iterative reconstruction does not substantially delay CT imaging in an emergency setting. Insights Imaging 4:391–397CrossRefPubMedPubMedCentral Willemink MJ, Schilham AM, Leiner T, Mali WP, de Jong PA, Budde RP (2013) Iterative reconstruction does not substantially delay CT imaging in an emergency setting. Insights Imaging 4:391–397CrossRefPubMedPubMedCentral
20.
go back to reference Mehta D, Thompson R, Morton T, Dhanantwari A, Shefer E (2013) Iterative model reconstruction: Simultaneously lowered computed tomography radiation dose and improved image quality. Med Phys Int 1:147–155 Mehta D, Thompson R, Morton T, Dhanantwari A, Shefer E (2013) Iterative model reconstruction: Simultaneously lowered computed tomography radiation dose and improved image quality. Med Phys Int 1:147–155
21.
go back to reference Yuki H, Oda S, Utsunomiya D et al (2016) Clinical impact of model-based type iterative reconstruction with fast reconstruction time on image quality of low-dose screening chest CT. Acta Radiol 57:295–302CrossRefPubMed Yuki H, Oda S, Utsunomiya D et al (2016) Clinical impact of model-based type iterative reconstruction with fast reconstruction time on image quality of low-dose screening chest CT. Acta Radiol 57:295–302CrossRefPubMed
22.
go back to reference Ichikawa Y, Kitagawa K, Nagasawa N, Murashima S, Sakuma H (2013) CT of the chest with model-based, fully iterative reconstruction: Comparison with adaptive statistical iterative reconstruction. BMC Med Imaging 13:27–2342CrossRefPubMedPubMedCentral Ichikawa Y, Kitagawa K, Nagasawa N, Murashima S, Sakuma H (2013) CT of the chest with model-based, fully iterative reconstruction: Comparison with adaptive statistical iterative reconstruction. BMC Med Imaging 13:27–2342CrossRefPubMedPubMedCentral
23.
go back to reference Pickhardt PJ, Lubner MG, Kim DH et al (2012) Abdominal CT with model-based iterative reconstruction (MBIR): Initial results of a prospective trial comparing ultralow-dose with standard-dose imaging. AJR Am J Roentgenol 199:1266–1274CrossRefPubMedPubMedCentral Pickhardt PJ, Lubner MG, Kim DH et al (2012) Abdominal CT with model-based iterative reconstruction (MBIR): Initial results of a prospective trial comparing ultralow-dose with standard-dose imaging. AJR Am J Roentgenol 199:1266–1274CrossRefPubMedPubMedCentral
24.
go back to reference Shen J, Du X, Guo D et al (2013) Prospective ECG-triggered coronary CT angiography: Clinical value of noise-based tube current reduction method with iterative reconstruction. PLoS One 8:e65025CrossRefPubMedPubMedCentral Shen J, Du X, Guo D et al (2013) Prospective ECG-triggered coronary CT angiography: Clinical value of noise-based tube current reduction method with iterative reconstruction. PLoS One 8:e65025CrossRefPubMedPubMedCentral
25.
go back to reference Botsikas D, Stefanelli S, Boudabbous S, Toso S, Becker CD, Montet X (2014) Model-based iterative reconstruction versus adaptive statistical iterative reconstruction in low-dose abdominal CT for urolithiasis. AJR Am J Roentgenol 203:336–340CrossRefPubMed Botsikas D, Stefanelli S, Boudabbous S, Toso S, Becker CD, Montet X (2014) Model-based iterative reconstruction versus adaptive statistical iterative reconstruction in low-dose abdominal CT for urolithiasis. AJR Am J Roentgenol 203:336–340CrossRefPubMed
Metadata
Title
Radiation dose reduction for CT assessment of urolithiasis using iterative reconstruction: A prospective intra-individual study
Authors
Annemarie M. den Harder
Martin J. Willemink
Pieter J. van Doormaal
Frank J. Wessels
M. T. W. T. Lock
Arnold M. R. Schilham
Ricardo P. J. Budde
Tim Leiner
Pim A. de Jong
Publication date
01-01-2018
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 1/2018
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-017-4929-2

Other articles of this Issue 1/2018

European Radiology 1/2018 Go to the issue