Published in:
01-12-2007 | Original Article
Pulmonary Kaposi sarcoma in six children
Authors:
Salomine Theron, Savvas Andronikou, Jaco Du Plessis, Pierre Goussard, Reena George, Ayanda Mapukata, Marie Grobbelaar, Murray Hayes, Nicky Wieselthaler, Alan Davidson
Published in:
Pediatric Radiology
|
Issue 12/2007
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Abstract
Background
Pulmonary involvement in Kaposi sarcoma is rare in children and can be difficult to distinguish from other pathology.
Objective
To describe the radiological findings in paediatric pulmonary Kaposi sarcoma.
Materials and methods
Sequential chest radiographs of six children and CT scans of four of these children were evaluated retrospectively. Their ages ranged from 18 months to 10 years; four were male and two were female. All six children were HIV-positive. The observers were two radiologists.
Results
Chest radiographs revealed air-space (100%) and reticular (83%) opacification in the mid- and lower lung zones; pleural effusions were present in 83% of the children. All the children showed progressive air-space opacification on follow-up radiography. CT demonstrated bilateral air-space opacification in a perihilar distribution in all the children; reticular opacification was seen in 75%. All the children had mediastinal and axillary lymphadenopathy; 75% had bilateral hilar lymphadenopathy.
Conclusion
In both adults and children, chest radiography demonstrates perihilar and lower zone involvement. Pleural effusions are more common on radiographs in children. Air-space disease and lymphadenopathy are much more common on CT in children than adults.