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Clinical Rheumatology
Published in: Clinical Rheumatology 11/2009

01-11-2009 | Case Report

Psoriatic arthritis and chronic lymphoedema: treatment efficacy by adalimumab

Authors: Denise Tong, Sharron Eather, Nicholas Manolios

Published in: Clinical Rheumatology | Issue 11/2009

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Abstract

Lymphoedema is a rare complication of psoriatic arthritis (PsA) and inflammatory joint disease, with no response noted to disease-modifying drugs. However, reports are emerging of a beneficial effect on lymphoedema in patients treated with tumor necrosis factor-alpha antagonists for PsA (Etanercept), rheumatoid arthritis (Etanercept) and ankylosing spondylitis (Infliximab). We describe a psoriatic arthritis patient whose lymphoedema greatly improved following commencement of adalimumab.
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Salvarini C, Macchiono PL, Veneziani M et al (1990) Upper limb lymphedema in PsA. J Rheumatolo 17:273–4
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Bohm M, Riemann B, Luger T et al (2000) Bilateral upper limb lymphoedema associated with PsA: a case report and review of the literature. Brit Journ Derm 143:1297–1301CrossRef
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Almodovar R, Zarco P, Quiros F et al (2004) Infliximab treatment efficacy in lymphoedema associated with ankylosing spondylitis. Rheumatology 43:1456–1458PubMedCrossRef
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Cantini F, Salvarani C, Olivieri I et al (2001) Distal extremity swelling with pitting edema in PsA: a case-control study. Clin Exp Rheumatol 19:291PubMed
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Salvarani C, Cantini F, Oliveri I et al (1999) Distal extremity swelling with pitting edema in PsA: evidence of 2 pathological mechanisms. J Rheumatol 26:1831PubMed
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Cha HS, Bae EK, Koh JH, Chai JY, Jeon CH, Ahn KS, Kim J, Koh EM (2007) Tumor necrosis factor-alpha induces vascular endothelialgrowth factor-C expression in rheumatoid synoviocytes. J Rheumatol 34:16–19PubMed
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Metadata
Title
Psoriatic arthritis and chronic lymphoedema: treatment efficacy by adalimumab
Authors
Denise Tong
Sharron Eather
Nicholas Manolios
Publication date
01-11-2009
Publisher
Springer-Verlag
Published in
Clinical Rheumatology / Issue 11/2009
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-009-1259-z

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Keynote webinar | Spotlight on medication adherence

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