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American Journal of Clinical Dermatology
Published in: American Journal of Clinical Dermatology 1/2024

16-11-2023 | Pruritus | Review Article

What’s New in Cutaneous T-Cell Lymphoma-Associated Pruritus

Authors: Georgia Biazus Soares, Joan Guitart, Gil Yosipovitch

Published in: American Journal of Clinical Dermatology | Issue 1/2024

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Abstract

Cutaneous T-cell lymphomas are a heterogenous group of lymphomas that cause various skin manifestations. Severe pruritus occurs frequently in cutaneous T-cell lymphoma and negatively impacts patients’ quality of life. The pathophysiology of cutaneous T-cell lymphoma-associated itch is complex and involves various immune cells, inflammatory cytokines, and neuroimmune interactions. Treating cutaneous T-cell lymphoma pruritus can be challenging, and there have been few randomized controlled studies evaluating the use of antipruritic treatments in these patients. Systemic therapies targeting the disease have also been shown to have some antipruritic effects. Furthermore, although biologic therapy has revolutionized the treatment of other pruritic skin conditions, the use of biologics in cutaneous T-cell lymphoma remains controversial.
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Metadata
Title
What’s New in Cutaneous T-Cell Lymphoma-Associated Pruritus
Authors
Georgia Biazus Soares
Joan Guitart
Gil Yosipovitch
Publication date
16-11-2023
Publisher
Springer International Publishing
Published in
American Journal of Clinical Dermatology / Issue 1/2024
Print ISSN: 1175-0561
Electronic ISSN: 1179-1888
DOI
https://doi.org/10.1007/s40257-023-00823-2

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