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European Journal of Orthopaedic Surgery & Traumatology

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01-05-2020 | Prosthetic Knee Joint Infection | Letter to the Editor

Letter to the Editor regarding “Serum interleukin 6 could be a valuable initial diagnostic tool in prosthetic knee joint infections”

Author: Nicolas Gallardo-Molina

Published in: European Journal of Orthopaedic Surgery & Traumatology | Issue 4/2020

Excerpt

The article by Majors et al. [1] provides a significant information for orthopedic surgery, especially in the placement of a prosthetic joint due to its main complication, which is an infection. Biomarkers are an effective tool to determine a possible prosthetic joint infection (PJI). The main ones are C-reactive protein (CRP), erythrosedimentation grade (ESR), white blood cells in synovial fluid (WBC) and polymorphonuclear leukocytes (PMN) in synovial fluid. In addition, the author focused on evaluating interleukin 6 (IL-6) as a diagnostic tool for PJI in the knee. Although more evidence is needed to establish the most effective predictors of PJI, other recent studies show different biomarkers that may or may not help with this diagnosis. …

Majors I, Jagadale VS (2019) Serum interleukin 6 could be a valuable initial diagnostic tool in prosthetic knee joint infections. Eur J Orthop Surg Traumatol 29(8):1781–1788CrossRef

Chen M-F, Chang C-H, Yang L-Y, Hsieh P-H, Shih H-N, Ueng SWN (2019) Synovial fluid interleukin-16, interleukin-18, and CRELD2 as novel biomarkers of prosthetic joint infections. Bone Jt Res 8(4):179–188CrossRef

Kleiss S, Jandl NM, Novo de Oliveira A, Rüther W, Niemeier A (2019) Diagnostic accuracy of alpha-defensin enzyme-linked immunosorbent assay in the clinical evaluation of painful hip and knee arthroplasty with possible prosthetic joint infection: a prospective study of 202 cases. Bone Jt J 101-B(8):970–977CrossRef

Shohat N, Tarabichi M, Tan TL, Goswami K, Kheir M, Malkani AL (2019) 2019 John Insall Award: Fructosamine is a better glycaemic marker compared with glycated haemoglobin (HbA1C) in predicting adverse outcomes following total knee arthroplasty: a prospective multicentre study. Bone Jt J 101-B:3–9CrossRef

Title: Letter to the Editor regarding “Serum interleukin 6 could be a valuable initial diagnostic tool in prosthetic knee joint infections”
Author: Nicolas Gallardo-Molina
Publication date: 01-05-2020
Publisher: Springer Paris
Keywords: Prosthetic Knee Joint Infection
Biomarkers
Published in: European Journal of Orthopaedic Surgery & Traumatology / Issue 4/2020
Print ISSN: 1633-8065
Electronic ISSN: 1432-1068
DOI: https://doi.org/10.1007/s00590-019-02620-2

At a glance: The STEP trials

Springer Medicine

Letter to the Editor regarding “Serum interleukin 6 could be a valuable initial diagnostic tool in prosthetic knee joint infections”

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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