Skip to main content
Top
Published in: Journal of General Internal Medicine 2/2020

01-11-2020 | Prostate Cancer | Original Research

Changing Provider PSA Screening Behavior Using Best Practice Advisories: Interventional Study in a Multispecialty Group Practice

Authors: Joseph Presti Jr, MD, Stacey Alexeeff, PhD, Brandon Horton, MPH, Stephanie Prausnitz, MS, Andrew L. Avins, MD, MPH

Published in: Journal of General Internal Medicine | Special Issue 2/2020

Login to get access

Abstract

Background

Most guidelines recommend against PSA-based screening for prostate cancer in men ≥ 70 years of age. Adherence to these guidelines is variable.

Objective

To determine whether the use of a “Best Practice Advisory” (BPA) intervention within the electronic medical record (EMR) system can alter the rate of PSA screening in men ≥ 70 years of age.

Design

This is an interventional study spanning the years 2013 through 2017, in men ≥ 70 years of age in Kaiser Permanente Northern California with no prior history of prostate cancer. The BPA intervention was activated in the EMR system on October 15, 2015, with no prior notice or education.

Setting

Integrated healthcare system including all Kaiser Permanente Northern California facilities.

Participants

A population-based sample that included all male members ≥ 70 years of age without a history of prostate cancer.

Main Measures

The main outcome was the rate of PSA testing in men ≥ 70 years of age. We compared the rates of PSA testing between the pre-BPA period (January 1, 2013–October 14, 2015) and the post-BPA period (October 15, 2015–December 31, 2017). An interrupted time series analysis of PSA ordering rates was performed.

Key Results

Following the 2015 BPA intervention, screening rates substantially declined from 36.0 per 100 person-years to 14.9 per 100 person-years (rate ratio = 0.415; 95% CI: 0.410–0.419). The effect of the BPA was comparable among all patient races and ordering provider specialties. The interrupted time series analysis showed a rapid, large, and sustained drop in the rate of PSA ordering, and much less temporal variation in test ordering after activation of the BPA.

Conclusion

Following activation of a BPA within the EMR, the rates of inappropriate PSA testing significantly declined by 58.5% in men ≥ 70 years of age and temporal variation was reduced.
Literature
1.
go back to reference Grossman DC, US Preventive Services Task Force. Screening for prostate cancer: US Preventive Services Task Force recommendation statement. JAMA. 2018;319(18):1901-1913.CrossRef Grossman DC, US Preventive Services Task Force. Screening for prostate cancer: US Preventive Services Task Force recommendation statement. JAMA. 2018;319(18):1901-1913.CrossRef
2.
go back to reference Qaseem A, Barry MJ, Denberg TD, Owens DK, Shekelle P, for the Clinical Guidelines Committee of the American College of Physicians. Screening for prostate cancer: A guidance statement from the Clinical Guidelines Committee of the American College of Physicians. Ann Intern Med. 2013;158(10):761-769.CrossRef Qaseem A, Barry MJ, Denberg TD, Owens DK, Shekelle P, for the Clinical Guidelines Committee of the American College of Physicians. Screening for prostate cancer: A guidance statement from the Clinical Guidelines Committee of the American College of Physicians. Ann Intern Med. 2013;158(10):761-769.CrossRef
4.
go back to reference Carter HB, Albertsen PC, Barry MJ, et al. Early detection of prostate cancer: AUA Guideline. J Urol. 2013;190(2):419-426.CrossRef Carter HB, Albertsen PC, Barry MJ, et al. Early detection of prostate cancer: AUA Guideline. J Urol. 2013;190(2):419-426.CrossRef
5.
go back to reference Schröder FH, Hugosson J, Roobol MJ, et al.. ERSPC Investigators. Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up. Lancet. 2014;384(9959):2027-2035.CrossRef Schröder FH, Hugosson J, Roobol MJ, et al.. ERSPC Investigators. Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up. Lancet. 2014;384(9959):2027-2035.CrossRef
6.
go back to reference Draisma G, Boer R, Otto SJ, et al. Lead times and overdetection due to prostate-specific antigen screening: Estimates form the European Randomized Study of Screening for Prostate Cancer. J Natl Cancer Inst. 2003;95:868-878.CrossRef Draisma G, Boer R, Otto SJ, et al. Lead times and overdetection due to prostate-specific antigen screening: Estimates form the European Randomized Study of Screening for Prostate Cancer. J Natl Cancer Inst. 2003;95:868-878.CrossRef
8.
go back to reference Bejjanki H, Mramba LK, Beal SG, et al. The role of a best practice alert in the electronic medical record in reducing repetitive lab tests. Clinicoecon Outcomes Res. 2018;10:611–618.CrossRef Bejjanki H, Mramba LK, Beal SG, et al. The role of a best practice alert in the electronic medical record in reducing repetitive lab tests. Clinicoecon Outcomes Res. 2018;10:611–618.CrossRef
9.
go back to reference Shelton JB, Ochotorena L, Bennett C, et al. Reducing PSA-based Prostate Cancer Screening in Men Aged 75 Years and Older with the Use of Highly Specific Computerized Clinical Decision Support. J Gen Intern Med. 2015;30(8):1133-1139.CrossRef Shelton JB, Ochotorena L, Bennett C, et al. Reducing PSA-based Prostate Cancer Screening in Men Aged 75 Years and Older with the Use of Highly Specific Computerized Clinical Decision Support. J Gen Intern Med. 2015;30(8):1133-1139.CrossRef
10.
go back to reference Bernal JL, Cummins S, Gasparrini A. Interrupted time series regression for the evaluation of public health interventions: a tutorial. Int J Epidemiol. 2017;46(1):348-355.PubMed Bernal JL, Cummins S, Gasparrini A. Interrupted time series regression for the evaluation of public health interventions: a tutorial. Int J Epidemiol. 2017;46(1):348-355.PubMed
11.
go back to reference Moyer VA. US Preventive Services Task Force. Screening for prostate cancer: US Preventive Services Task Force recommendation statement. Ann Intern Med. 2012;157(2):120-134.CrossRef Moyer VA. US Preventive Services Task Force. Screening for prostate cancer: US Preventive Services Task Force recommendation statement. Ann Intern Med. 2012;157(2):120-134.CrossRef
14.
go back to reference Walraven CV, Goel V, Chan B. Effect of population-based interventions on laboratory utilization – a time-series analysis. JAMA. 1998;280:2028-2033.CrossRef Walraven CV, Goel V, Chan B. Effect of population-based interventions on laboratory utilization – a time-series analysis. JAMA. 1998;280:2028-2033.CrossRef
15.
go back to reference Lin CP, Payne TH, Nichol WP, Hoey PJ, Anderson CL, Gennari JH. Evaluating Clinical Decision Support Systems: Monitoring CPOE Order Check Override Rates in the Department of Veterans Affairs’ Computerized Patient Record System. J Am Med Inform Assoc. 2008;15:620–626.CrossRef Lin CP, Payne TH, Nichol WP, Hoey PJ, Anderson CL, Gennari JH. Evaluating Clinical Decision Support Systems: Monitoring CPOE Order Check Override Rates in the Department of Veterans Affairs’ Computerized Patient Record System. J Am Med Inform Assoc. 2008;15:620–626.CrossRef
16.
go back to reference Feldman LS, Shihab HM, Thiemann D, et al. Impact of Providing Fee Data on Laboratory Test Ordering A Controlled Clinical Trial. JAMA Intern Med. 2013;173(10):903-908.CrossRef Feldman LS, Shihab HM, Thiemann D, et al. Impact of Providing Fee Data on Laboratory Test Ordering A Controlled Clinical Trial. JAMA Intern Med. 2013;173(10):903-908.CrossRef
17.
go back to reference Levick DL, Stern G, Meyerhoefer CD, Levick A, Pucklavage D. Reducing unnecessary testing in a CPOE system through implementation of a targeted CDS intervention. BMC Med Inform Decis Mak. 2013;13:43-49.CrossRef Levick DL, Stern G, Meyerhoefer CD, Levick A, Pucklavage D. Reducing unnecessary testing in a CPOE system through implementation of a targeted CDS intervention. BMC Med Inform Decis Mak. 2013;13:43-49.CrossRef
18.
go back to reference Najafi N, Cucina R, Pierre B, Khanna R. Assessment of a targeted electronic health record intervention to reduce telemetry duration: a cluster-randomized clinical trial. JAMA Intern Med. 2018;179(1):11-15.CrossRef Najafi N, Cucina R, Pierre B, Khanna R. Assessment of a targeted electronic health record intervention to reduce telemetry duration: a cluster-randomized clinical trial. JAMA Intern Med. 2018;179(1):11-15.CrossRef
Metadata
Title
Changing Provider PSA Screening Behavior Using Best Practice Advisories: Interventional Study in a Multispecialty Group Practice
Authors
Joseph Presti Jr, MD
Stacey Alexeeff, PhD
Brandon Horton, MPH
Stephanie Prausnitz, MS
Andrew L. Avins, MD, MPH
Publication date
01-11-2020
Publisher
Springer International Publishing
Published in
Journal of General Internal Medicine / Issue Special Issue 2/2020
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-020-06097-2

Other articles of this Special Issue 2/2020

Journal of General Internal Medicine 2/2020 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.