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01-01-2021 | Prostate Cancer | Case Report

Coexistence of brown tumors due to secondary hyperparathyroidism and prostate cancer in a patient

Authors: Ruben Abdala, Mariana S. Gonzalez Pernas

Published in: Osteoporosis International | Issue 1/2021

Abstract

We present the case of a 65-year-old man with brown tumors due to secondary hyperparathyroidism. Magnetic resonance imaging of the pelvis showed multiple lesions with expansive bone appearance. Additionally, prostate cancer was diagnosed during this time. For this reason, differential diagnosis was performed through biopsy of the right iliac bone lesion. Brown tumors are caused by osteoclastic activity and fibroblast proliferation; the differential diagnosis of these bone lesions includes giant tumors, metastases, Paget’s disease, and paraneoplastic syndrome with high levels of parathyroid hormone-related peptide (PTHrP). This case report describes the coexistence of two pathologies that could explain these images. In this report, we present a case of a 65-year-old man with brown tumors due to secondary hyperparathyroidism and prostate cancer. In this setting, histologic confirmation is recommended.

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Title: Coexistence of brown tumors due to secondary hyperparathyroidism and prostate cancer in a patient
Authors: Ruben Abdala
Mariana S. Gonzalez Pernas
Publication date: 01-01-2021
Publisher: Springer London
Keywords: Prostate Cancer
Hyperparathyroidism
Prostate Cancer
Paget's Disease of Bone
MRI of the Pelvis
Paraneoplastic Syndromes
Published in: Osteoporosis International / Issue 1/2021
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-020-05558-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Coexistence of brown tumors due to secondary hyperparathyroidism and prostate cancer in a patient

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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