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Published in: World Journal of Urology 4/2007

01-08-2007 | Review

Prostate cancer and markers of bone metabolism: diagnostic, prognostic, and therapeutic implications

Authors: Eric C. Nelson, Christopher P. Evans, Chong-Xian Pan, Primo N. Lara Jr

Published in: World Journal of Urology | Issue 4/2007

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Abstract

Knowledge of bone metastases complicating advanced prostate cancer (CaP) is increasingly relevant in patient selection for novel therapies. Current nuclear bone scintigraphy imaging has limited specificity for prostate metastases. As serum bone markers do correlate with bony lesions, they may play multiple roles in patients with advanced CaP. Currently, these markers play a role in prognostic nomograms for CaP. Recent studies suggest an expanding role for bone markers in the diagnosis and selection of patients for novel therapies. In the future, therapeutic roles for some of these marker pathways will emerge, eventually allowing greater individualization of patient care.
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Metadata
Title
Prostate cancer and markers of bone metabolism: diagnostic, prognostic, and therapeutic implications
Authors
Eric C. Nelson
Christopher P. Evans
Chong-Xian Pan
Primo N. Lara Jr
Publication date
01-08-2007
Publisher
Springer-Verlag
Published in
World Journal of Urology / Issue 4/2007
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-007-0186-3

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