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Current Urology Reports
Published in: Current Urology Reports 7/2017

01-07-2017 | Prostate Cancer (S Prasad, Section Editor)

Prostate Biopsy in Active Surveillance Protocols: Immediate Re-biopsy and Timing of Subsequent Biopsies

Authors: Jonathan H. Wang, Tracy M. Downs, E. Jason Abel, Kyle A. Richards, David F. Jarrard

Published in: Current Urology Reports | Issue 7/2017

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Abstract

Purpose of Review

This manuscript reviews contemporary literature regarding prostate cancer active surveillance (AS) protocols as well as other tools that may guide the management of biopsy frequency and assess the possibility of progression in low-risk prostate cancer.

Recent Findings

There is no consensus regarding the timing of surveillance biopsies; however, an immediate repeat biopsy within 12 months of diagnosis for patients considering AS confirms patients who have favorable risk disease yet also identifies patients who were undersampled initially. Studies regarding multiparametric MRI, nomograms, and biomarkers show promise in risk stratifying and counseling patients during AS. Further studies are needed to determine if these supplemental tests can decrease the frequency of surveillance biopsies.

Summary

An immediate re-biopsy can help to reduce the risk of missing clinically significant disease. Other clinical tools, including mpMRI, exist that can be used as an adjunct to counsel patients and guide a personalized discussion regarding the frequency of surveillance biopsies.
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Metadata
Title
Prostate Biopsy in Active Surveillance Protocols: Immediate Re-biopsy and Timing of Subsequent Biopsies
Authors
Jonathan H. Wang
Tracy M. Downs
E. Jason Abel
Kyle A. Richards
David F. Jarrard
Publication date
01-07-2017
Publisher
Springer US
Published in
Current Urology Reports / Issue 7/2017
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-017-0702-y

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