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Published in: Skeletal Radiology 3/2017

01-03-2017 | Scientific Article

Prospective pilot study of CT-guided microwave ablation in the treatment of osteoid osteomas

Authors: Clara Prud’homme, Jean-Philippe Nueffer, Michel Runge, Jonathan Dubut, Bruno Kastler, Sébastien Aubry

Published in: Skeletal Radiology | Issue 3/2017

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Abstract

Purpose

The aims of this work were to assess the feasibility and efficacy of CT-guided microwave ablation (MWA) in the treatment of osteoid osteomas (OOs).

Materials and methods

Thirteen consecutive patients (range 11–31 years old) presenting with OO were prospectively included and treated by CT-guided MWA. Power and duration of MWA were both recorded. The patient’s pain was assessed using a numeric pain rating scale (NRS), and side effects were recorded during procedures, after 1 day, 7 days and 1 month. The nidus vascularization and the volume of necrosis induced by MWA were assessed using contrast-enhanced MRI. Success was defined as the complete relief of the patient’s pain 1 month after the first procedure, associated with necrosis of the nidus on follow-up MRI.

Results

The success rate was up to 92.3% (12/13). At 1 day, 7 days and 1 month, the median NRSs were respectively 5 [interquartile range (IQR) 2–5], 0 (IQR 0–1) and 0 (IQR 0–0). Side effects observed were one partial and self-resolving lesion of a sensory branch of the radial nerve and two skin burns. The median power of the MWA used was 60 W (IQR 50–60) with a 1.5-min duration (IQR 1–2), leading to MWA-induced necrosis measuring on average 23 × 15 × 16 mm.

Conclusion

CT-guided MWA of OO has a success rate that appears to be almost similar to that of laser or radiofrequency ablation, but care must be taken to prevent nerve or skin lesions.
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Metadata
Title
Prospective pilot study of CT-guided microwave ablation in the treatment of osteoid osteomas
Authors
Clara Prud’homme
Jean-Philippe Nueffer
Michel Runge
Jonathan Dubut
Bruno Kastler
Sébastien Aubry
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 3/2017
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-016-2558-5

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