Published in:
01-05-2007 | Review Article
Progress of Study on the Relationship Between Mediators of Inflammation and Apoptosis in Acute Pancreatitis
Authors:
Xi-Ping Zhang, Qian Lin, Yi-Feng Zhou
Published in:
Digestive Diseases and Sciences
|
Issue 5/2007
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Abstract
As an important pathological feature of acute pancreatitis, apoptosis may occur in multiple organs and relate directly to the progression of disease. It is mainly controlled by the apoptosis gene and also influenced by inflammatory mediators. We summarize here the roles of the main inflammatory mediators (e.g., NO, TNF-α, TGF-β1, IL-10, NF-κB) during the pathologic process of acute pancreatitis.